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Biomedical subjects

A Hjortrup

Publications and source records attributed to A Hjortrup.

89 records · Page 5Linked to original sources
PubMed1983

Long-term clinical effects of ovarian wedge resection in polycystic ovarian syndrome.

Twenty-nine consecutive patients with polycystic ovary (PCO) syndrome (defined as hirsutism plus oligomenorrhea or secondary amenorrhea, and excluding Cushing's syndrome, an androgen-secreting adrenal or ovarian tumor or adrenocortical hyperplasia) were treated with ovarian wedge resection leaving normal-sized ovaries. Long-term follow-up from 2.3-9.5 years (mean 5.7 years) showed that 26 of 29 patients (90%) had established normal menstrual cycles. Fertility and normal pregnancies were achieved in all 10 patients (100%) with normal postoperative menstrual cycles who desired to conceive, but not in the 3 patients with remaining postoperative oligomenorrhea. Eight of 9 patients who were obese preoperatively and who had normal postoperative menstrual cycles showed a major weight loss after wedge resection. In contrast, none of the preoperatively obese patients, who remained oligomenorrheic after surgery, lost weight. Hirsutism was not cured by wedge resection. It is concluded that ovarian wedge resection should still be considered useful in patients with PCO.

Amenorrhea↗
PubMed1982

Urinary incontinence and genital prolapse: a prospective blind study of the value of urodynamic evaluation.

The value of urodynamic examination was studied in 44 women treated for genital prolapse and/or urinary incontinence. A preoperative urodynamic examination was done but not considered in the planning of the operations. The treatment performed after clinical examination was identical to that proposed after urodynamic evaluation in 20 of 34 incontinent patients (59 per cent), while the treatments differed in 14 (41 per cent). The results were considerably better 6 months postoperatively in the former than in the latter patients. Of the 44 patients 11 (25 per cent) had detrusor instability, which resolved 6 months postoperatively in 4 and the symptoms had vanished or decreased in 6.

Adult↗
PubMed1982

Extrarenal angiomyolipoma: diagnosis and management.

We review the symptoms, diagnosis and treatment of extrarenal and renal angiomyolipomas. The pathological anatomy is described and it is maintained that renal localization of angiomyolipoma is by far the most common. A case is reported of an extrarenal angiomyolipoma that was revealed by exploratory laparotomy. Treatment is always surgical, since it is difficult to establish the differential diagnosis preoperatively. Angiomyolipoma is a benign tumor and malignant degeneration has not been observed. However, there is a tendency toward recurrence if the entire tumor is not removed.

Adult↗
PubMed1982

Sphincter-saving resection of the rectum using the EEA autostapler.

Low anterior resection for carcinoma in the mid- and lower third of the rectum has been performed with autosuture technique, using the EEA autosuture stapling instrument in 38 patients, 26 with carcinoma, 10 with diverticulitis, and 2 with Crohn's disease. In 16 patients the anastomotic line was 4-6 cm above the anal verge, and in 22 patients 7-12 cm above the anal verge. Thirty-two patients (80%) had an uneventful postoperative course. Four patients had complications: one, with leakage from a very low-seated anastomosis, was treated with an abdominoperineal resection; 2 had temporary transversostomy performed due to minor anastomotic leakage; and 1 patient developed a fistula, which closed spontaneously. Two patients died, 1 from pulmonary embolism, 1 from cerebral thrombosis. The EEA stapling instrument seems safe, and approximately 42% of the patients in this material would formerly have been subjected to abdominoperineal resection and permanent colostomy.

Adult↗
PubMed1981

Bladder dysfunction after low anterior resection for mid-rectal cancer.

Twenty consecutive patients with carcinoma 7 to 12 cm from the anus underwent radical low anterior resection of the rectum; the anastomosis was performed by the EEA stapling instrument. One patient died from pulmonary complications. On urologic follow-up 6 to 8 months after the operation, five patients had significant symptoms from the urinary tract, and in three patients denervation of the bladder was demonstrated. The study establishes that bladder paresis, which is a well-known complication after extirpation of the rectum, also may follow very low anterior resection with anastomosis. The importance of careful follow-up is emphasized

Aged↗
PubMed1981

Long-term results of surgery for carcinoid tumours of the gastro-intestinal tract.

54 patients were followed-up 1-22 years (median 11 years) after histological verification of a carcinoid tumour. four patients died before operation; 41 patients had their lesion in the appendix, 13 in different extra appendiceal sites in the gastrointestinal tract. There was a significant difference between the median ages and the mortality rates in the two groups. Only one patient with an appendiceal tumour died of his disease. Appendiceal carcinoid, even with local spreading to the serosa and local lymph nodes, seemed to be adequately treated by a simple appendectomy. Extensive surgery, following the principles of treatment for malignant tumours, should be undertaken, when spread to the caecum or ascending colon is present or when the tumour is of extra-appendiceal origin.

Adolescent↗
PubMed1980

Anterior resection for mid-rectal cancer with the EEA stapling instrument.

Early results of resection with primary anastomosis for cancer of the mid-rectum using a new stapling instrument are reported. Thirty patients with an adenocarcinoma 7 to 12 cm from the anal verge were operated on. One patient died postoperatively from respiratory complications but with no sign of anastomotic dehiscence. Two patients had a clinically recognizable leak that closed spontaneously within 3 days. Three patients had roentgenologically demonstrable leakage but no clinical symptoms. On examination 2 to 11 months after operation, all patients were continent for feces as well as gas, and none had more than four bowel movements per day. In four patients, all with a roentgenologically demonstrable leak, a stricture developed at the anastomosis within 3 months after discharge. All four patients were successfully treated by dilatation. Resection with anastomosis by means of the stapling instrument is practical even at the lowest level, is far less time-consuming and does not require the same degree of training as low anterior resection with conventional suture anastomosis.

Adenocarcinoma↗
PubMedDate not supplied

Antibiotic prophylaxis in high risk biliary surgery: one dose of ceftriaxone compared with two doses of cefuroxime.

In a controlled trial 219 high risk patients undergoing biliary surgery were allocated at random by sealed envelopes to one of two treatment groups. Group I (n = 112) received a single dose ceftriaxone 1 g intravenously at the time of skin incision, and group II (n = 107) was given cefuroxime 1.5 g intravenously at the time of skin incision, followed by a second dose eight hours later. There were no significant differences between groups in age, sex, diagnosis, or operations carried out. There were three wound infections in group I (3%) and four in group II (4%) (p = 0.65). One patient in group I and two patients in group II developed intra-abdominal abscess and septicaemia (0.9% and 1.9%, respectively). Five patients developed pneumonia postoperatively in group I (5%) and six in group II (6%) (p = 0.65). There was no significant difference of the total number of postoperative infectious complications (wound infection, intraabdominal abscess, septicaemia, and pneumonia) between the groups (p = 0.42). A single dose of ceftriaxone given intravenously at skin incision was as effective as two doses of cefuroxime for the prophylaxis of wound infection in this high risk group of patients.

Abscess↗
PubMedDate not supplied

Linear incision and curettage vs. deroofing and drainage in subcutaneous abscess. A randomized clinical trial.

Linear incision plus curettage under antibiotic cover was compared with conventional deroofing and drainage of subcutaneous abscess in a randomized study of 50 patients. The median healing time was 9 days following linear incision and curettage and 15 days after deroofing and drainage (p less than 0.05). There was no recurrence of abscess during follow-up for 6 months. Linear incision plus curettage under single-dose antibiotic cover thus proved to be a safe method with significantly shorter healing time than after conventional deroofing an drainage.

Abscess↗