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At least 127 records · Page 7Linked to original sources

[Does lymphography affect the healing results in cervix cancer?].

The therapeutical results of patients suffering from cervical cancer have been proofed in a clinical retrospective study in two groups with and without preoperative lymphography. 321 patients operated on by abdominal and vaginal route in the years 1976-1981 were included. It could be demonstrated, that survival rate is not better after lymphography independent from histological type and stage or postoperative irradiation. Therefore the value of preoperative lymphography may be doubtful.

Adult↗

[Value of lymphography, computer tomography and ultrasound in the diagnosis of infradiaphragmatic malignant lymphomas in children].

25 children with Hodgkin's disease and 6 children with Non-Hodgkin-lymphoma were reviewed in order to compare the diagnostic value of lymphography, CT and sonography. As compared with staging-laparotomy, sensitivity for the detection of lymph node involvement was 78% for lymphography, 33% for CT and 57% for the ultrasound examination. Specifity was 55%, 88%, and 83% respectively. Undetected involvement of splenic and liver hilar lymph nodes, unspecific lymphadenitis and fluid-filled bowl loops caused most of the false negative and false positive findings. In 10 children histological examination showed splenic involvement. No splenic lesion was seen by CT in 7 of these children. Splenic disease could be clearly identified by ultrasound in only one child. Although children with lymph node involvement had always splenic manifestations of malignant lymphomatous disease it is concluded that staging laparotomy is an indispensable tool in diagnosing malignant lymphoma. Lymphography should not be abandoned with children. It should be used in combination with either CT or ultrasound examination.

Abdominal Neoplasms↗

[The histologically evaluated accuracy of lymphography in operative therapy of invasive cervix cancer stages Ib-IIb].

118 of 129 pre-operative patients with invasive cervical carcinoma of stage Ib to IIb from 1974 to 1978 were examined lymphographically. Abdominal radical hysterectomy according to Wertheim with obligatory lymphonodectomy followed in all cases. Results of the histologic examination of lymphnodes have been compared with the findings from lymphography, whereby a coincidence could be proved in 84 per cent of all cases. The correlation for the lumbar and iliac lymphonodi was listed separately in 75 per cent of the cases. Lymphography gives significantly better results within the lumbar region with an accuracy rate of 92 per cent, a sensitivity of 100 per cent and a specificity of 98.5 per cent. It may be concluded that a lumbar lymphonodectomy is not necessary in the event of a negative lymphography.

Female↗

Pulmonary oil deposition in patients subjected to lymphography: Detection by thoracic photoscan and sputum examination.

During clinical trials of intralymphatic therapy with radioiodinated ethiodized oil (Lipiodol Ultra-Fluid; Ethiodol) [LUF-I(131)] for malignant disease involving lymph nodes, significant pulmonary deposition of radioactive material was demonstrated by thoracic scan in each of five cases treated. Radioactivity was detected in sputum obtained from two cases. Induced sputum specimens were subsequently obtained from patients undergoing lymphography. Fat demonstrated in sputum was confirmed as Lipiodol in one of six patients tested. Sputum examination and use of tracer doses of LUF-I(131) plus photoscanning are suggested as sensitive methods of assessing the incidence of oil deposition in the lungs of patients undergoing lymphography. Despite limitation of the volume of oil injected, monitoring of the infusion, and absence of radiographic evidence of contrast medium in the lungs, some degree of pulmonary oil deposition appears to be an inevitable result of lymphography. Further study of lung dosimetry is being undertaken by the authors before clinical usage of endolymphatic radioisotope therapy is expanded.

Ethiodized Oil↗

[Lymphography in malignant vulvar and vaginal tumors. 1. Clinical significance].

The results of a retrograde analysis of lymphographic processes in 111 patients with malign vulvar and vaginal tumours are substantiating statements concerning the importance of lymphography in diagnosing metastastic processes in lymph-nodes of the inguinal and retroperitoneal region. -- Metastases could be proved lymphographically in 24 (34%) out of 70 carcinomas of the vulva and 8 (22%) out of 37 carcinomas of the vagina. In 24% of all patients with carcinomas of the vulva there were lymph-nodes involved, in two of these cases without a simultaneous involvement of the inguinal region. With carcinomas of the vagina a lumbar involvement was found in 50% of the cases. The accuracy of lymphographic diagnosis was 79% regarding the inguinal region and 89% in the iliac region. Despite of the lower accuracy with regard to inguinal lymph-nodes lymphography exceeds findings obtained by clinical palpation in this respect. As a result of the study, the use of lymphography in case of vulvar and vaginal carcinomas of all clinical stages is considered to be profitable for diagnosing and therapy planning.

Aged↗

[Accuracy of lymphography in carcinoma of the cervix (author's transl)].

A review has been made of lymphographic diagnoses recorded from patients with cervical carcinoma over more than five years. The diagnosis by lymphography of nodes metastases had to be altered in some 25 per cent, and correction proved necessary also in cases in which lymphography had failed to yield conclusive information. - In the group with lymphographically secured cancer lymph nodes coincided with histological results in 70 per cent of all primary and 90 per cent of secondary checks. Comparable gaps were recorded also from the group with lymphographically inconclusive information on lymph node cancer. - The following conclusions are drawn from the study described: (a) The accuracy of lymphographic diagnosis depends on the experiences of the examiner and changes within time and this must be considered in the evaluation of therapeutic success or failure. - (b) Conclusive findings in the context of lymph node problems are obtainable from selective use of lymphography.

Carcinoma, Squamous Cell↗

[Neurologic complication of lymphography. Apropos of a case].

A lymphography was performed as a diagnostic procedure in a 69-year-old female patient hospitalized for protracted fever. Akinetic mutism with left hemiparesis occurred 10 minutes after the injection of ultrafluid lipiodol. The patient died 13 days later. Neurologic complications of lymphography are extremely rare but may be life-threatening. Speculations as to the mechanisms which may be responsible for these complications, through a modification of the usual distribution of the contrast media, include lymphovenous shunts, lymphatic vessel compression or obstruction, pulmonary arteriovenous shunts and right-to-left intracardiac shunts. These mechanisms may facilitate cerebral embolization of the contrast media. Indications of lymphography must be restricted in patients with patent lymphatic obstruction.

Aged↗

[Value of lymphography in teratoid testicular tumors (author's transl)].

In 72 patients with malignant testicular tumors lymphograms were reviewed and correlated with the microscopic findings of the resected lymphnodes. In 55 patients (76%) the roentgenographic diagnosis was confirmed by histology. In 6 patients lymphography was false positive as microscopic examination of the resected lymphnodes showed. In 4 patients lymphography was considered negative but metastatic disease proven microscopically from retroperitoneal lymphnodes. Out of 7 patients with questionable positive lymphograms 2 had retroperitoneal metastases confirmed by microscopic examination. The limits, errors and value of lymphography in patients with testicular tumors are discussed.

Adolescent↗

Lymphography.

Lymphography is a valuable diagnostic procedure that may be declining in use due to the amount of time required for a radiologist to perform the procedure. Technologist participation in lymphography may be a means to allow better utilization of the radiologist's time, while improving diagnostic accuracy and reducing health care costs. This paper presents an overview of lymphography and details the technologist's role in the procedure.

Coloring Agents↗

[Role and aspects of lymphography in juvenile chronic polyarthritis].

The authors report two cases of Still's disease with unusual presentation, characterized by important paraaortic lymphatic nodes. The findings of the lymphography could not distinguish between Hodgkin's disease, lymphoma, or inflammatory hyperplasia. Lymphography is usually of little interest for the diagnostic of Still's disease. However the knowledge of such misleading aspects is important when unusual clinical manifestations lead to perform a lymphography.

Arthritis, Juvenile↗

Accuracy of lymphography in staging of prostatic and bladder carcinoma: 88 cases with aspirative cytological and postlymphadenectomy histological verification.

Lymphography was performed in 88 patients with prostatic (n = 51) or bladder (n = 37) carcinoma. The lymphographic findings were correlated to the cytological and histological staging obtained by means of transcutaneous fine-needle aspiration biopsy and/or pelvic lymphadenectomy performed after lymphography on the most frequently involved glands. The lymphographic diagnosis was confirmed in 90.7% of the patients. In 16 cases (18.1%) histology was not in accordance with the positive lymphogram and in 5 cases (5.6%) lymphography was false negative. The authors emphasize the high rate (35.5%) of normal-sized nodes with evident but minimal metastatic changes, cytohistologically verified. These are, in fact, metastatic lymphonodal lesions which escape ultrasonography and computed tomography.

Aged↗

Detection of neoplastic lymph node involvement in the retroperitoneal space. Diagnostic value of CT, echography and lymphography.

The diagnostic value of echography, computerized tomography and lymphography in the detection of infiltrating retroperitoneal lymph nodes was assessed in a prospective study. Ninety-six patients suffering from Hodgkin's disease, non-Hodgkin lymphoma, seminomatous and and non-seminomatous tumours of the testis were examined with all three methods. Sixty-two (30 non-seminomas, 32 Hodgkin's diseases) had an exploratory laparotomy at least one week after the diagnostic examinations. Sensitivity and specificity were assessed on the basis of the pathohistological findings. The sensitivity was 92% for CT, 79% for echography and 83% for lymphography. The specificity was 89% for CT, 95% for echography and 84% for lymphography. The presented findings suggest that a re-evaluation of the diagnostic strategy in assessment of lesions involving retroperitoneal lymph node is required.

Humans↗

[Value of lymphography in prostatic cancer - comparison with pelvic en-bloc lymphadenectomy].

On the basis of 62 pelvic en bloc lymphadenectomies in the carcinoma of the prostate the lymphogenic formation of metastases is histologically determined. In 41 patients the comparison between lymphographic and histological N-determination is performed. The security of the lymphography in the carcinoma of the prostate in the lymphographically establishable pelvic region is recognized with 70%. By the pelvic en bloc lymphadenectomy in 50% of the cases a change of the preoperatively established N-determination takes place. The pedal lymphography is overestimated as method in the carcinoma of the prostate. As a secure technique in the determination of the lymphogenic formation of metastases at present the pelvic en bloc lymphadenomectomy with histological elaboration of the preparations is to be regarded. To this methods belongs a decisive diagnostic evidence in the determination of the formation of metastases of the carcinoma of the prostate by pelvic lymph nodes. The value of the lymphography consists in the simultaneous establishment of aortic metastases. Apart from this an intraoperative X-ray control may partly prove the radicality of the intervention.

Humans↗

[CT and lymphography correlations in the evaluation of patients with testicular tumours (author's transl)].

27 patients with testicular tumours were examined by lymphography and computerized tomography for evaluation of metastatic spread in the retroperitoneal lymphnodes. A good correlation of results was found in 23 patients. In 4 cases lymphography failed to show metastatic disease, which was easily recognized by CT. In account of the lymphatic spread pathways of testicular tumours leading mainly to the lymphnodes close to the kidney pedicle CT appears to be method of choice in the staging of these patients, as the lymphnodes in this area are often not demonstrated by lymphography. Computerized tomography allows the exact localisation and extension of neoplastic lymphnodes and at the same time a good evaluation of the surrounding organs.

Dysgerminoma↗

Lymphography and CEA in the diagnosis of metastases in patients with stage IB cancer of the cervix.

Fifty-nine patients with Stage IB cancer of the cervix underwent lymphography and were screened for carcinoembryonic antigen (CEA) levels before radical hysterectomy with pelvic lymph node dissection. Very strict criteria were used in the evaluation of the lymphograms in order to avoid false positive results. CEA levels were determined in plasma with a modified CEA-Roche kit, and values over 5 micrograms/liter considered as positive. Lymphography: Approximately 20% of the pelvic lymph node metastases could be detected in films taken 24 hours after the injection of the contrast medium. In patients subjected to combined treatment with intracavitary radium followed by operation, control lymphograms were taken preoperatively, 6 weeks after the radium insertions. In these films the metastases detection rate was 55%, with no false positive lymphograms. CEA: Levels over 5 micrograms/liter were found in 13 patients. Pelvic lymph node metastases were found in 10 of them, giving a metastases detection rate of 42%. One patient with lung metastases and one patient with metastases in the ovaries also has elevated levels of CEA. There was one patient with "false positive" elevation of CEA. The combination of CEA determinations and lymphography 6 weeks after the radium treatment yielded a total pelvic lymph node metastasis rate of 85%.

Carcinoembryonic Antigen↗

[Different evaluations of the staging of Hodgkin's and non-Hodgkin's lymphomas (NHL) with computer tomography and lymphography by different observers].

In this report, the differences in the evaluation of CT and lymphography findings by different observers is discussed. The study included 132 men and 79 women (146 NHL and 65 Hodgkin lymphomas). A total of 185 CT examinations and 78 lymphographies were available for reevaluation. In the lymphographies, discongruent findings were reported twice as frequently as in the CT scans (15% and 9%). An optimized examination protocol for CT and consistent criteria for the interpretation of lymphographic findings could possible lead to a better diagnostic evaluation.

Adolescent↗

Tc-99m diethylenetriamine pentaacetic acid (DTPA)-human serum albumin (HSA) radionuclide lymphography for detecting the location of chyluria.

The cause of chyluria cannot be easily detected by CT scan or other imaging methods, except conventional lymphography, but Tc-99m diethylenetriamine pentaacetic acid radionuclide lymphography clearly revealed the location of chyluria in the left renal pelvic area. Radionuclide lymphography is one of the choices in investigating chyluria due to its noninvasive and simple technique.

Aged↗

[Contrast media for magnetic resonance tomographic lymph node diagnosis (MR lymphography)].

In MR-imaging, similar to computed tomography, diagnosis of metastatic lymph-node disease is based on lymph-node sizes, and thereby it is non-specific. Super-paramagnetic iron oxide as a potential contrast medium for MR-lymphography accumulate in normal lymph node tissue after endolymphatic, interstitial and, in case of very small particles, after intravenous injection. No accumulation occures in lymph node metastases. Lymph-node metastases can be detected by all three injection techniques. It has been shown experimentally, that in particular small metastases can be detected in normal sized lymph nodes. However, MR-lymphography also has inherent methodologic problems, as there may occure an uneven distribution of the contrast medium between different lymph-node groups. The experimental results with endolymphatic, interstitial, and intravenous MR-lymphography as well as first clinical results with intravenous contrast medium injection are presented and discussed.

Contrast Media↗