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An articulated ankle external fixation system that can be aligned with the ankle axis.

Aligning an articulated ankle external fixator with the ankle axis located using a mechanical axis finder has been shown to preserve normal ankle joint kinematics while the fixed hinge device is attached. However, several problems exist preventing the clinical application of this finding for fractures of the tibial plafond. We initiated a series of studies to resolve these issues. First, the accuracy of the mechanical axis finder in biological systems was quantified by comparing it to that of a computationally derived helical axis. Second, a prototype fixator design was developed in the biomechanics lab to increase the versatility of intraoperative fixator placement. Finally, a radiographic method of locating the ankle axis was developed which is based on talar morphology independent of the fractured tibia. The prototype fixator has been accurately aligned along the ankle axis in cadaveric specimens using this method. Open reduction and internal fixation (ORIF) is the accepted method of treatment for tibial plafond fractures. It holds the advantage of sufficient fracture fixation to permit early joint motion. Good results have been reported using this method, but some authors have reported complication rates up to 50%. The wide surgical approaches required, in conjunction with preexisting soft tissue injury, are thought to significantly increase the risk of soft tissue complications. In response to these problems, many investigators are beginning to utilize external fixation as an alternate treatment modality. One external fixation system which has shown particularly good results is a monolateral cross-ankle articulated fixator (Orthofix SRL., Verona, Italy) which allows motion at the ankle joint as the plafond fracture is healing (Figure 1).(ABSTRACT TRUNCATED AT 250 WORDS)

Ankle Joint↗

Establishment of the formalin-free surgical pathology laboratory. Utility of an alcohol-based fixative.

Concerns about the toxicity of formalin dictate the need for alternative methods of tissue fixation. Alcohol-based fixatives have been proposed as optimal for immunohistochemical and nucleic acid methods and may be useful for diagnostic light microscopy. We recently converted our surgical pathology laboratory from 10% neutral buffered formalin to an alcoholic fixative (56% ethanol and 20% polyethylene glycol) and compared 100 consecutive cases after conversion with 100 formalin-fixed cases prior to conversion. One representative slide from each case was reviewed independently by four pathologists without knowledge of the fixative employed. The quality of fixation of each case was graded (0, very poor; 1, below average; 2, average; and 3, above average) based on the subjective composite evaluation of seven morphological features: tissue architecture, cell borders, cytoplasm, nuclear contours, chromatin texture, red blood cell membranes, and uniformity of staining. No significant difference in the quality of fixation was observed, although the average score of the alcoholic fixative was slightly lower than that of the formalin (2.59 vs 2.74). Interobserver concordance was 74%. Advantages of the alcoholic fixative included elimination of carcinogenic vapors, more rapid fixation, greater stain avidity, elimination of enzyme predigestion in immunohistochemical studies, and simple and rapid disposal. Disadvantages included slightly increased viscosity, increased variability of tissue staining and nuclear shrinkage, artifactual pigment deposition in bloody specimens, and increased flammability risk. Alcohol-polyethylene glycol appears to be a satisfactory alternative to formalin in routine diagnostic surgical pathology.

Ethanol↗

Methods of microwave fixation for microscopy. A review of research and clinical applications: 1970-1992.

Microwave fixation methods are important because excellent preservation of both cell structure and antigenicity can be attained several orders of magnitude faster than by routine chemical fixation methods. Fast and ultrafast microwave fixation have yielded significant logistic advantages over another fast fixation approach-rapid freezing at liquid helium temperatures. For example, specimens used for microwave fixation can be as large as 1 cm3 and cells can remain in suspension. We review in detail both qualitative and quantitative morphologic results obtained by using microwave fixation in sample preparation. We provide tables of biological molecules that are preserved in a variety of human and animal tissues by various microwave fixation methods for histochemistry, immunohistochemistry, cytochemistry, immunocytochemistry, and affinity labelling studies. Limitations of large cavity (e.g., household) microwave ovens often result in irreproducible fixation results. We present calibration and standardization protocols for microwave fixation in large cavity microwave ovens that emphasize a) localization of oven hot spots (i.e., high power) using a neon bulb array, b) magnetron warm-up, c) the use of a water load, d) the use of an agar-saline-Giemsa model to predict the uniformity of irradiation in small samples, e) the use of specimen containers with one dimension less than 1.5 cm, and f) fast specimen handling to prevent conductive heating artifacts after irradiation. Although microwave ovens are commonplace their unique applications in the laboratory environment require special safety considerations, which are reviewed. Advances in microwave technology are providing new means to study the structure-function relationships of cellular and biochemical activities.

Animals↗

Femoral lengthening: callotasis with Ilizarov external fixator alone and with intramedullary locking nail.

Callus distraction (callotasis) has improved the results of limb lengthening and has decreased complication rates. Unfortunately, this technique requires a long time in an external fixator device to allow bone regeneration and consolidation, especially in adults. We retrospectively compared the results and complications of two groups of patients who underwent femoral lengthening by means of callotasis with the Ilizarov external fixator. Group I underwent callotasis alone, and group II underwent callotasis with an intramedullary locking nail. Group I consisted of 14 patients, with a median age at surgery of 24.3 years. Group I etiologies were trauma in seven patients, congenital disorders in four and sequelae of poliomyelitis in three. Group II consisted of seven patients, with a median age at surgery of 22.4 years. The etiologies in group II were trauma in five patients and congenital disorders in two. In group I, the median gain in length was 4 cm. The median time in the external fixator was 218 days. The median time index of external fixation was 50 days/cm. Complications included four pin tract infections, one incomplete corticotomy, one refracture and one flexion contracture after removal of the external fixator. In group II, the median gain in length was 4.8 cm, and the median time in the external fixator was 70 days. The median time index of external fixation was 14 days/cm. There were no major complications except one distal screw backout, which did not impair the final outcome. We conclude that femoral lengthening by callotasis with combined Ilizarov external fixator and intramedullary locking nail can significantly shorten the treatment in the external fixator period, with good results and low complication rates in adults.

Adolescent↗

Fixation disparity and accommodation as a function of viewing distance and prism load.

Fixation disparity was measured with dichoptically presented nonius lines at viewing distances of 20, 30, 40, 60, and 100 cm, so that both vergence and accommodation were stimulated adequately as in normal vision. As the viewing distance was shortened, mean fixation disparity changed monotonically from 1 min arc eso (i.e., the eyes converged in front of the target) to 3 min arc exo. The average standard deviation of the psychometric function of fixation disparity, which is a measure of the temporal variability of vergence, was smallest at 100 cm (when fixation disparity was eso) and increased as viewing distance decreased. Fixation disparity itself and the change of fixation disparity with distance differed reliably among subjects with normal binocular vision, but neither was related to the momentary degree of accommodation. Fixation disparity was also measured at a constant distance of 40 cm, but with prisms in front of the eyes that induced the same vergence angles as viewing distances between 20 and 100 cm. The slope of these conventional fixation disparity curves as a function of prism load was generally larger than the slope of fixation disparity as a function of viewing distance (which can be explained by accommodative vergence), but the slopes of the two types of curves were correlated (r = 0.39, P = 0.02, n = 25).

Accommodation, Ocular↗

[Cytophotometric determination of non-heme iron in hepatocytes. II. Effect of fixation on the cell iron content].

The study deals with the effect of different fixatives, such as absolute methanol, 96% ethanol, 10% buffered neutral formalin, as well as mixtures: methanol-formalin-acetic acid and ethanol-formalin-acetic acid (Tellesnitsky's solution) on preservation of iron in isolated hepatocytes of rats on a diet with addition of 2% carbonyl iron. The iron preservation in cells, on application of different fixatives and performance of Perls' reaction, was evaluated by the intensity of cell staining that was measured using cytospectrophotometer. The best preservation of iron in cells has been achieved when using alcohol fixatives only. Fixation of preparations with the methanol-formalin-aceticacid mixture also produced no decrease in the iron content in hepatocytes, however, morphology of the stained cells was much worse than after methanol and ethanol fixation. Fixation with Tellesnitsky's solution resulted in a 36% reduction of the cellular iron content, whereas fixation with 10% neutral formalin reduced iron content by 58%, as compared with methanol fixation. A prolongation formalin fixation from 10 min to 24 hr had no effect on the intensity of Perls' reaction.

Animals↗

Treatment of periprosthetic fractures in association with total hip arthroplasty--a retrospective comparison between revision stem and plate fixation.

BACKGROUND AND AIMS: In periprosthetic fracture associated with hip arthroplasty, no consensus exists about the use of plate fixation or revision stem except for cases where the stem is loose in a young patient and a revision is made. The aim of the present retrospective study was to compare two commonly used alternatives for treatment of the fracture--revision arthroplasty and plate fixation. MATERIAL AND METHODS: Seventy-five fractures associated with total hip arthroplasty were treated with revision arthroplasty (N = 40) or compression plate fixation (N = 35). Twenty-one fractures were intraoperative and 54 were postoperative. In revision arthroplasty, cemented (N = 11) and porous-coated (N = 29) stems were sued. Autologous bone grafts were used in 15 revision arthroplasties and 20 plate fixations. The follow-up time was median 20 months (range 12-96 months). RESULTS: Bone grafting at the time of fracture treatment had no significant effect on fracture healing in the present setting. One patient in both groups was operated secondarily because of fracture instability. Five nonunions in the former and 9 nonunions in the latter group were treated by repeated revision and bone graft. In two revision arthroplasties and nine cases with plate fixation, a secondary bone grafting operation was performed for delayed union. In all, 20 secondary operations were needed after prosthesis stem revision and 27 secondary operations after plate fixation (p = 0.014). The need for reoperations was similar in fractures at different levels of the femur. Fracture healing was finally obtained in 39 revision arthroplasties and 34 cases with plate fixation during the follow-up period. CONCLUSIONS: Cases where the prosthesis stem is stable, where its removal would include great risks and, where the biomechanical conditions are optimal, are best treated with plate fixation. In cases where the stem is loose and where a choice is possible, stem revision is preferable to plate fixation.

Adult↗

Robot-assisted versus freehand cannulated-screw fixation for femoral neck fractures: a systematic review of technical, clinical and adoption outcomes.

Robot-assisted guidance may improve the technical precision of percutaneous cannulated-screw fixation for femoral neck fractures. Whether these procedural advantages translate into better clinical outcomes remains uncertain. We compared robot-assisted and conventional freehand fixation in adults with femoral neck fractures. MEDLINE, Embase and CINAHL were searched from inception to 15 July 2026 without language restrictions. Google Scholar was used only as a supplementary search source, together with forward and backward citation searching. Comparative studies of robot-assisted versus freehand fluoroscopy-guided cannulated-screw fixation were included. Risk of bias was assessed using RoB 2 and ROBINS-I, with the Newcastle-Ottawa Scale used as a complementary appraisal of non-randomised studies. Random-effects meta-analyses included prediction intervals and prespecified sensitivity analyses. The protocol was registered prospectively (PROSPERO CRD420261465038). Sixteen comparative studies involving 1,293 participants were included. Of these, 597 underwent robot-assisted fixation and 696 underwent freehand fixation. Two studies reporting random allocation and 14 non-randomised studies were included in the study. Robot-assisted fixation was associated with fewer guide-wire manipulations, greater screw-placement accuracy and 13.9 fewer fluoroscopic acquisitions per procedure (95% confidence interval [CI] -20.3 to -7.5). Earlier radiographic healing and modestly higher final Harris Hip Scores were also observed. Pooled estimates suggested lower risks of union failure, avascular necrosis and composite complications. Fluoroscopy duration, overall operative time and reoperation did not differ significantly. Heterogeneity was substantial for several continuous outcomes, with prediction intervals crossing the null for several estimates, indicating that the magnitude of benefit varied considerably between studies. Some clinical associations were also sensitive to eligibility-restricted analyses. Robot-assisted cannulated-screw fixation improves technical execution compared with freehand fixation. Patient-important clinical superiority and economic value have not been established, and evidence concerning learning curves, operator acceptability and system reliability remains insufficient. Current evidence does not support routine widespread adoption; adequately powered multicentre randomised trials incorporating economic and implementation evaluation are required.

Humans↗

[Healing of spiral fractures in the sheep tibia comparing different methods--osteosynthesis with internal fixation, interlocking nailing and dynamic compression plate].

The healing process of spiral fractures of the sheep tibia was investigated in an experiment with simulated clinical conditions. The effects of conventional internal fixation techniques with the DCP and the intramedullary nail are compared with those of internal fixation with the spine fixator. The internal fixation techniques are described in terms of their bending stiffness when mounted on the fractured bone. The in vivo investigation was documented clinically and radiographically and the post mortem specimens were evaluated histologically. The bending stiffness of the healed bone was assessed in relation to the contralateral side. After application of the DCP, primary healing took place and extensive transcortical necrosis occurred in the implant bed. Intramedullary nailing led to secondary healing and to necrosis of the inner cortex close to the endosteum. After internal fixation with the spine fixator, gap healing took place and no cortical necrosis was observed. The clinical course was generally good after all procedures. The histological evaluation shows that damage to the vascularity of the bone can only be avoided by using the spine fixator. This principle seems to be appropriate for the purposes of biological internal fixation.

Animals↗

Effect of continuous circular capsulorhexis and intraocular lens fixation on the blood-aqueous barrier.

Permeability across the blood-aqueous barrier to fluorescein was estimated fluorophotometrically in pseudophakic eyes for which a continuous circular capsulorhexis was performed. The permeability index was significantly higher in the in-the-bag fixations than in the out-of-the-bag fixations at 3 and 6 months after surgery, when only bilateral cases were enrolled. Damage to the barrier in eyes with the in-the-bag fixations was attributable to the broad attachment of optics to the anterior capsule, because a positive linear regression was obtained between the permeability index and the doughnut-shaped contact area in eyes with the in-the-bag fixations. The permeability index in eyes with the in-the-bag fixations was as low as that in eyes with the out-of-the-bag fixations when the contact area was small. These results indicate an unfavorable effect of the in-the-bag fixation with broad contact of the optics with the anterior capsule and, thus, suggest either an in-the-bag fixation with a large capsulorhexis or an out-of-the-bag fixation.

Adult↗

Effects of radiation treatment planning and patient fixation on the results of postoperative radiotherapy of childhood medulloblastoma.

PURPOSE: To assess the prognostic factors and the benefit of introducing head fixation and CT-assisted radiation treatment planning following postoperative radiotherapy in 83 children with medulloblastoma. PATIENTS AND METHODS: In 24 children treated between 1986 and 1994, no head fixation was applied and boost irradiation was not based on individual radiation treatment planning. Since 1995, boost irradiation has been assisted by CT-based individual radiation treatment planning and ORFIT head fixation in 59 patients. The influence of various factors including age, sex, tumor location, extent, type of surgery, risk group, radiation dose to posterior fossa and spinal axis, and the effect of head fixation and CT-assisted radiation treatment planning on 5-year relapse-free and 5-year overall survival was investigated. RESULTS: Overall and relapse-free survival rates for all 83 patients were 73.5% and 60.7%. Univariate analysis identified metastatic disease (p = 0.034) and the application of head fixation and individual radiation treatment planning (p = 0.013) as significant prognostic factors for overall survival. Relapse-free survival rates were influenced by metastatic disease (p = 0.028) and the application of head fixation and individual radiation treatment planning (p = 0.009). On multivariate analysis, metastatic disease (p = 0.04) and the application of head fixation and individual radiation treatment planning (p = 0.045) were significant factors for overall and relapse-free survival (p = 0.036 and p = 0.041) as well. CONCLUSION: Metastatic disease appears to be correlated with a worse prognosis in this analysis. Individual radiation treatment planning and head fixation have a positive impact on survival. For postoperative radiotherapy of the posterior fossa, the application of head fixation and individual CT-based radiation treatment planning is considered indispensable in each case.

Adolescent↗

[Principles of fixation of the cementless modular revision stem Revitan].

AIM AND METHOD: To analyse the femoral fixation of a modular cementless revision endoprosthesis, eight prosthetic combinations of the Revitan-System (Centerpulse, Winterthur, Switzerland) were implanted in four cadavers. On three cadavers a curved revision Revitan stem was implanted by an endofemoral approach on one side and by a transfemoral approach on the contralateral side. On the fourth cadaver a straight Revitan stem was implanted on one side and a curved Revitan stem on the contralateral side using a transfemoral approach. Transversal slides of 7-8 mm thickness were performed at the fixation areas of each implant and the implant-bone contact was analysed macroscopically and using contact radiography. RESULTS: The straight stem implanted by a transfemoral approach showed a double-conical press-fit fixation with cutting of the eight longitudinal fins into the cortical bone. The curved revision stems implanted by the same approach had a circular surface fixation similar to the press-fit fixation of the straight stem. In contrast, the curved stems implanted by the endofemoral approach (without a window) showed a three-surface fixation. Hereby the two distal fixation areas led to the primary implant stability by three of the four double edges of the octagonal cross-sectional area cutting into the cortical bone. At the proximal fixation zone the implant only had contact of two implant double edges to the cortical bone. CONCLUSION: Different approaches for implantation lead to different fixation techniques of a curved revision stem. This should be considered by analysing postoperative sintering rates of cementless revision stems.

Aged↗

Experimental results of mesh fixation by a manual manipulator in a laparoscopic inguinal hernia repair model.

BACKGROUND: Laparoscopic mesh fixation using a stapler can lead to complications such as nerve injury and bowel injury. However, mesh fixation by suturing with conventional laparoscopic instruments (CLI) is difficult because of limited degrees of freedom. A manual manipulator--Radius Surgical System (Radius)--whose tip can deflect and rotate, gives the surgeon two additional degrees of freedom. The aim of this study is to evaluate the introduction of Radius to mesh fixation in laparoscopic inguinal hernia repair. METHODS: A model for inguinal hernia repair was prepared using animal organs in a trainer. Mesh fixation was performed using Radius, stapler, and CLI. Tensile strength during extraction of mesh toward the vertical direction, and execution time, were measured. RESULTS: The mean number of fixation points of Radius, stapler, and CLI was 9.3 +/- 1.5, 8.5 +/- 1.4, and 9.0 +/- 1.0, respectively. The mean tensile strength of fixation of mesh of Radius, stapler, and CLI was 140.7 +/- 48.9, 73.1 +/- 23.4, and 53.6 +/- 31.5 (N), respectively. The mean tensile strength per one fixation point by Radius, stapler, and CLI was 16.5 +/- 5.3, 8.7 +/- 2.8, and 6.3 +/- 3.6 (N), respectively. The mean execution time of Radius, stapler, and CLI was 479 +/- 108, 54 +/- 31, and 431 +/- 77 (sec), respectively. CONCLUSIONS: The mesh fixation by Radius was stronger than that by staples and CLI. Two additional degrees of freedom were useful in difficult angles. The introduction of Radius is feasible and facilitates the fixation of mesh with sutures in laparoscopic inguinal hernia repair.

Animals↗

The mechanism of the control of carbon fixation by the pH in the chloroplast stroma. Studies with nitrite-mediated proton transfer across the envelope.

1. CO2 fixation of intact spinach chloroplasts is inhibited by nitrite in a pH-dependent mode. At pH 7.3 in the medium 1 mM NaNO2 and at pH 7.9 5 mM NaNO2 were required for 50% inhibition. 2. The addition of nitrite leads to an acidificiation in the stroma. It appears that nitrite renders the envelope permeable for protons resulting in a breakdown of the pH gradient between the external space and the stroma. 3. In view of earlier results on the pH sensitivity of C02 fixation it is concluded that this pH shift in the stroma is responsible for the observed inhibition of CO2 fixation by nitrite. 4. Octanoate and to some extent also high concentrations of bicarbonate and acetate have a similar effect as nitrite in inhibiting CO2 fixation through an acidification in the stroma. 5. The levels of the intermediates of the CO2 fixation cycle were measured. A strong rise of the levels of fructose- and sedoheptulose biphosphates and a concomitant decrease of the corresponding monophosphates was observed during inhibition of CO2 fixation. It appears that the enzymatic steps of the CO2 fixation cycle responsible for the overall inhibition of CO2 fixation caused by lowering of the H+ concentration in the stroma are fructose- and sedopheptulose bisphosphatase. These two enzymes have an important function in the light regulation of CO2 fixation.

Ammonium Chloride↗

Clinical and biomechanical aspects of external fixation of the pelvis.

OBJECTIVE: The aim was to evaluate the mechanical stability of several traditional and modern external fixators in unstable pelvic ring disruption. DESIGN: In a laboratory study external and internal fixation techniques were tested in seven fresh and five embalmed human pelves with a disruption of the pubic symphysis and one sacroiliac joint (type C1.2 injury according to the Tile-AO classification). BACKGROUND: Stability provided by external fixation depends upon many factors, with the residual pelvic stability being the most important. METHODS: Simulating a single-leg stance, the load was applied quasi-statically to the acetabulum of the unstable hemipelvis. Device failure was defined as displacement >10 mm either at the symphysis pubis or the sacroiliac joint. RESULTS: The frame with the highest failure load (fresh versus embalmed specimens) was the Egbers configuration with the AO fixator (analysis of variance; P < 0.05). Failure was noted at 114.9 N versus 129.5 N. Augmentation of the Mono-Tube by additional internal posterior osteosynthesis gave the following results: sacral bars 325.4 N versus 217.8 N, plate fixation 294.3 N versus 215.8 N, lag screws 338.4 N versus 215.8 N. Failure loads of hybrid fixation of the Orthofix were as follows: sacral bars 257.9 N versus 213.9 N, plate fixation 333.5 N versus 245.3 N, lag screws 397.3 N versus 280.6 N. The differences between the two fixators were not statistically significant. CONCLUSIONS: No single external frame provided sufficient stability. The addition of a posterior internal fixation significantly increased failure loads and controlled the weight-bearing pelvic elements.

Journal Article↗

Hybrid fixation improves structural properties of a free tendon anterior cruciate ligament reconstruction.

PURPOSE: This study sought to characterize the structural properties of a combined bioabsorbable interference screw and closed loop and button fixation technique (Hybrid) for femoral fixation of a free tendon graft versus a bioabsorbable interference screw or closed loop and button suspension fixation method alone. METHODS: Eighteen porcine femora and quadrupled cadaveric flexor tendons were treated in 3 experimental fixation study groups: (1) closed loop and button suspension (CLBS), (2) bioabsorbable interference screw (BIF), and (3) closed loop and button suspension with supplemental biodegradable interference screw (Hybrid). An Instron testing machine (Instron, Canton, MA) was used to quantify each group's structural properties with cyclic loading and tensile load-to-failure. A video digitizing system measured graft deformation during load-to-failure. RESULTS: The Hybrid fixation group had significantly greater structural properties compared with the CLBS or BIF group. Ultimate loads (mean [SEM] in Newtons) were 1184 (88) N, 813 (83) N, and 561 (62) N for the Hybrid fixation group, CLBS group, and BIF group, respectively. Quasi-steady state cyclic stiffness (mean [SEM] in Newtons per millimeter) was also greatest for the Hybrid fixation group at 165 (11) N/mm, compared with CLBS (122 [8] N/mm), and BIF (95 [9] N/mm). CONCLUSIONS: Femoral free tendon hybrid fixation provides superior structural properties under tensile and cyclic displacement conditions while preserving the working length of the native anterior cruciate ligament. CLINICAL RELEVANCE: Hybrid femoral fixation may minimize postoperative laxity for free tendon anterior cruciate ligament reconstruction.

Absorbable Implants↗

Current of injury predicts adequate active lead fixation in permanent pacemaker/defibrillation leads.

OBJECTIVES: The aim of this study was to determine whether current of injury can guide adequate placement of active-fixation pacing leads. BACKGROUND: Active-fixation leads cause injury to the myocardium at the time of fixation, manifested as a current of injury (COI) that may result in acute elevation of pacing thresholds. The relationship of COI to subsequent improvement in pacing thresholds is not clear. METHODS: Sixty-five patients undergoing active-fixation lead implantation were enrolled. Current of injury was characterized as the duration of the intracardiac electrogram (EGM) and the magnitude of ST-segment elevation. Pacing parameters were measured up to 10 min after fixation. RESULTS: A total of 96 active-fixation leads were studied, and 76 leads had a current of injury. From baseline to the time of fixation, the duration of the intracardiac EGM in ventricular leads increased from 150 +/- 31 ms to 200 +/- 25 ms (p < 0.001), and the ST-segment increased from 1.5 +/- 0.2 mV to 10.0 +/- 2.0 mV (p < 0.001), with subsequent improvement in pacing thresholds from 1.5 +/- 0.4 V to 0.8 +/- 0.3 V (p < 0.001) at 10 min. Atrial leads with a current of injury had similar findings. Of the 20 leads without a COI, 5 dislodged acutely and 15 had high pacing thresholds at 10 min, requiring repositioning. CONCLUSIONS: The development of a COI indicates that within 10 min of fixation, pacing threshold will return to an acceptable range even if the initial measurement is high. Conversely, without a COI, lead fixation is not adequate and the lead should be repositioned.

Aged↗

The comparative strength of laryngeal fracture fixation.

PURPOSE: To assess the fixation strength provided by miniplate fixation, wire-tube batten fixation, and wire fixation alone in repair of thyroid cartilage. MATERIALS AND METHODS: Segments 2.5-cm wide x 1-cm long were cut from three fresh, frozen, human cadaveric larynges from an 83-year-old man, a 58-year-old woman, and an unknown cadaver. A vertical fracture was induced and repaired with one of three randomly assigned fixation techniques (n=10 in each fixation group). The repaired cartilage was placed in an Instron Universal Testing Device (Boston, MA) and subjected to a three-point bending test. Load to failure was recorded on an analogue graph. RESULTS: All reconstruction techniques significantly differed from each other, with miniplate fixation providing a stronger repair than wire tube batten (P < .05), wire tube batten providing a stronger repair than wire alone (P < .01), and miniplate providing a stronger repair than wire alone (P < .001). CONCLUSION: In experimentally induced fractures of the human larynx, miniplate fixation consistently yielded the strongest repair. Although both miniplate and wire batten produced excellent anatomic reaction, we feel that miniplate fixation was easier to perform.

Aged↗