[The computer in the dental office. 1. Ergonomics and microprocessing].
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Radiology reports are likely to be more useful if they contain appropriate graphic material. Diagnostic conclusions and recommendations become more convincing and useful when the clinician personally can review the image on which these are based. Modern desk-top publishing techniques make it possible to incorporate radiographic images, appropriately selected and annotated, as part of the radiology report. It is believed that such illustrated reports would be preferred by referring physicians, notwithstanding a significant loss of image detail. A survey of these referring physicians was carried out to determine whether this hypothesis was correct.
The Department of Anesthesiology and Critical Care Medicine (DACCM) has substantially upgraded its computer resources within the past two years by installing a local area network (LAN) and replacing low-end PC's with PC's utilizing Intel 80286 or 80386 microprocessor technology. Data base development has now become a priority. Data bases are being developed for both clinical and administrative purposes. We are replacing the traditional method of "keypunching" with optical card scanners which results in faster and more accurate data entry directly into the data bases. Previously, such card scanners have been confined to large organizations. We describe a method of data capture and data base development with wide applicability in medicine.
The principle of recording vectorcardiographic loops with a microdot thermal printer is developed using a very small memory area. It is based on two previous achievements: (i) orthogonal electocardiogram derivation from the conventional 12-lead system and (ii) recoding of biomedical signals with a microdot thermal printer, thus permitting the VCG to be just an extension of the standard ECG. The principle consists of decomposing the loop into horizontal sectors each one representing a non-ambigous function. It is implemented in ECG instruments, using the Gotemba microdot thermal printers TLP 480Z and TLP 880Z produced in Japan.
The application of a mini computer to a routine diagnostic vascular laboratory has been assessed in over 4,500 patients over a period of 5 years. The laboratory functions to provide diagnosis of peripheral vascular disease. The computer functions are: scientific, in which it is used for modelling the arterial system and for applying diagnostic algorithms using haemodynamic signals re-input data, data base management, in which it is used to store clinical histories, the results of haemodynamic tests, and data for reconstructive surgery, and administrative, in which it is used for laboratory booking, report generation and management and workload statistics.
The authors present the principles of work of a computer system destined for evaluation of the results of routine electrophysiological examination of two muscles and four sensory nerves in alcohol-dependent subjects. The range of examinations and the programme based on discrimination analysis make possible, as shown in own investigations, an objective and complete evaluation of the state of the peripheral nervous system in these subjects. The programme is owned by the EMG laboratory of the Institute of Psychiatry and Neurology in Warsaw where it was introduced for clinical diagnosis, but it may be made available to other persons interested in these problems. An electromyograph with a stimulator with current exit averager and minicomputer, e.g. Commodore 64 with a printer are necessary.
We present a new method for evaluating in vivo changes in bone mineralization in the peripheral skeleton, using computed tomography (CT). A set of bone mineralization indices are generated from numerous CT images of the patient's distal radius. The cross-sectional anatomy displayed by the CT scan allows for separate evaluation of the cortical and trabecular bone. Correction for possible drift of the CT number scale (Hounsfield scale) is achieved by scanning standard solutions of dipotassium hydrogen phosphate simultaneously with the forearm. Preliminary data indicate that this is a precise method for evaluating in vivo changes in bone mineralization.
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High-resolution computed tomography (HRCT) was performed on 15 patients who had diffuse peripheral lung disease, and the findings were compared with those of conventional chest radiography and histologic examination. Bullae, interstitial fibrosis with honeycombing, and small granulomas were more clearly and specifically demonstrated on HRCT scans than on conventional chest radiographs in all patients. Histologically proved mild alveolar wall thickening due to alveolitis in cases of sarcoidosis and systemic lupus erythematosus was not detected. HRCT is useful for performing detailed morphological analyses of abnormalities of the peripheral portions of the lung.
Robotic-assisted bronchoscopy (RAB) and computed tomography-guided transthoracic biopsy (CTTB) are competing strategies for sampling peripheral pulmonary lesions (PPLs). Whether they differ in yield or safety is uncertain. To our knowledge, this is the first systematic review restricted to direct comparisons. We searched MEDLINE, Europe PMC, Scopus, Web of Science and ClinicalTrials.gov from inception to 7 July 2026 for studies directly comparing RAB with CTTB in adults with PPLs. The primary outcome was strict 2024 American Thoracic Society/American College of Chest Physicians diagnostic yield. Risk of bias was assessed with ROBINS-I and certainty with GRADE. A cohort-genealogy step identified, per outcome, the largest set of cohorts sharing no patients; only that set was pooled, with Hartung-Knapp and Mantel-Haenszel sensitivity analyses. Five retrospective studies from one US health system were eligible. Four share patients; at most three cohorts are mutually independent. Across those three, diagnostic yield was comparable (risk ratio [RR] 0.99, 95% confidence interval [CI] 0.93-1.06; I²=24%; Hartung-Knapp 0.87-1.13), with an identical relative effect under strict and intermediate definitions although absolute yields fell from 88% to 74-84% under strict criteria. Pneumothorax requiring a chest tube and/or admission was about three-quarters less frequent with RAB across all three cohorts (RR 0.25, 95% CI 0.14-0.46; I²=0%; Hartung-Knapp 0.07-0.96). Strict yield (RR 0.99) and any pneumothorax (RR 0.06) were reported by two cohorts each and neither survives the few-studies correction. RAB took about 50 min longer than CTTB where same-session staging endobronchial ultrasound was counted in the robotic time, but only about 8 min longer than CTTB where it was not. Only one cohort reported yield by lesion size category and none reported yield by bronchus sign or lung zone, so lesion-level subgroups could not be pooled. Certainty was low for pleural complications and very low elsewhere. Low-certainty evidence indicates that RAB is associated with fewer pleural complications, with no statistically detectable difference in diagnostic yield; equivalence was not formally established. Because all evidence is retrospective, confined to one health system, and almost never stratified by lesion size or accessibility, these findings are hypothesis-generating and require a multicenter randomized trial.
In seven patients with active fascioliasis of the liver, CT revealed nodular intrahepatic lesions of diminished attenuation, as well as peripheral branching formations. Computed tomography was negative in a single patient with quiescent disease. Computed tomography can be a useful tool for the diagnosis of this disease during the invasive period and also to evaluate response of patients to medical treatment.
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Insulin metabolism in man is usually investigated by peripheral injection of the hormone, whereas native insulin undergoes hepatic extraction prior to mixing in the general circulation. To quantify this difference, in 10 dogs [125I] insulin was injected into a peripheral vein, and the initial distribution volume (IDV), the metabolic clearance rate (MCR), and the mean transit time (t) were computed from the plasma disappearance curve of the immunoprecipitable activity. The splenic vein was then cannulated under pentobarbital anesthesia, and the parameters were again computed from the peripheral activity after portal introduction of the tracer. The MCR after portal injection [15.1 +/- (SE) 1.1 ml/min per kg] was greater (P is less than 0.001) than the MCR after peripheral administration (13.4 +/- 0.9 ml/min per kg). Also, IDV was larger (P is less than 0.01) after portal injection (167 +/- 12 vs. 138 +/- 10 ml/kg). Mean transit times did not change significantly. Insulin secretion rate (0.29 +/-0.04 mU/min per kg) and body insulin mass (7.03 +/- 1.5 mU/kg) were also measured. An estimate of hepatic extraction was obtained from the difference between the clearance rate values calculated following portal and peripheral injection. Under our experimental conditions, hepatic retention of insulin was found to be 19.6% (range 9.6-36.2%). The method is recommended for investigations in man.
An algorithm to assist in the computation of routine peripheral nystagmus slow phase velocity (SPV) has been implemented on an Apple based data acquisition system. Waveforms stored by the computer may be output to a dot matrix printer to complement conventional strip-chart recorder output. An estimate of SPV is available after each caloric session. Analysis modes range from a summarized output for inclusion in the clinical report to a detailed beat by beat report comprising waveforms, markers and tabulated results. Problematic signals, beyond the scope of the automatic analysis, may be inspected interactively using a software controlled cursor.
After pulsed peripheral olfactory impulses it is possible, under suitable testing conditions, for specific sensory potentials to be read from the surface of the skull and, after repetitions, added up (olfactorially evoked cortical potentials). Typically, there developes a so-called twin-potential containing the equivalents of the electrical activites of the nervus trigeminus and the nervus olfactorius in two peaks of the cortex equivalents. In an objective manner, in other words without intentional or vegetative influence by the test person, it is possible by the weakening or lack of one or the other or both part-potentials to obtain information about the functioning of the olfactory sense. Typical examples will be presented.
Recently, medical information processing systems applying computers have achieved marked advances in parallel with the development of highly accurate automatic measuring instruments. The authors already in 1974 developed and reported a computerized automatic audiometer containing a micro-computer which stored a program for audiometric procedures. Subsequently the authors have developed a compact, multi-purpose audiometric instrument which executes the standard air-bone conduction audiometry, with the exclusion of masking, automatically with a built-in micro-computer. An outline of the instrument is as follows: 1. The instrument is composed of a memory, a control unit, programs for data processing and measurement, a character display for instructing subjects and an audiogram display. It can be operated manually in the same way as a conventional audiometer. 2. Test errors and any abnormally large differences between the responses of the two ears can be detected automatically, and the tests can then be re-executed manually after finishing the automatic procedure for correction of the data. 3. The instrument is provided with output terminals for connection to an external computer or other peripheral equipment. It is designed to be compact and light weight.
The first reported findings on CT and N.M.R. in two cases of idiopathic peripheral lymphoedema are described. These methods have compared with the generally available volume estimations (volume estimation according to Kuhnke, immersion plethysmography) and have been considered in relation to visual and lymphographic examinations.
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