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An experimental resource centre on handicap in children. 2. Results from one year's operation.

An experimental resource centre on handicap for professional workers in four London boroughs as well advertised through all the relevant social, health and education departments. It provided a wide range of reference and display material as well as a programme of 20 lectures from experts with different backgrounds. The response to the centre by the various professions is reported, both in respect of visits to use its resources and of attendance at seminars and lectures. The response was disappointing, particularly from social workers and teachers. The centre had to close from lack of support after one year. Possible causes for the lack of response are discussed, and suggestions are made as to how the quality of the service given to handicapped children and their families can be improved.

Attitude of Health Personnel↗

A history of nursing: a history of caring?

The history of nursing is, itself, a fit subject for research. It is unclear what would constitute history in this case, its time frame or its methodology. It is also the case that the purpose of history needs exploration, since it can meet many goals, including the goal of professionalization. This paper explores these issues in some detail, using examples from the literature in the history of nursing. It explores historical inquiry and purpose and the problems of sources. The paper also addresses the relationship between the history of nursing and nursing theory and questions whether existing historical scholarship is integrated with or is outwith mainstream nursing theory. The paper questions the relevance of the history of nursing and suggests that the history of caring may offer one way through history to nursing theory.

Culture↗

Teachers in general practice: a comparative study.

Thirty-nine randomly selected general practitioners in the Cambridgeshire Health Area were surveyed in an attempt to determine whether there were prior differences between those practitioners who choose to become involved with undergraduate medical students and those who choose not to. Teachers were found to have graduated more recently, subscribe to more journals and were more likely to use medical libraries than non-teachers. All the solo practitioners in the study and two of the four practitioners in two-man groups belonged to a subgroup of non-teachers who had never had students and did not want students in the future. This subfroup also subscribed to fewer journals than the other groups, bought fewer textbooks and used medical libraries less. The only prior differences between teachers and non-teacher that have been demonstrated are year of graduation and type of practice. Other differences could well be attributed to the influence of the students themselves. Studies are needed to clarify this issue, especially as it realates to continuing medical education.

Education, Medical, Continuing↗

Systematic review of thromboprophylaxis in colorectal surgery -- an update.

OBJECTIVE: The incidence of thromboembolism after colorectal surgery is higher than after general surgery. The aim of this paper is to update a systematic review addressing thrombosis prophylaxis in connection with colorectal surgery. METHODS: MEDLINE, EMBASE, LILACS, abstract books and reference lists from reviews were searched without language restrictions for randomized controlled trials or clinical controlled trials comparing prophylactic interventions and/or placebo up til August 2003. Five hundred and fifty-eight studies were identified of which 19 fulfilled the inclusion criteria. Data extraction was done by at least two of the authors. Outcome was deep venous thrombosis and/or pulmonary embolism diagnosed by various methods. RESULTS: Any kind of heparin is better than no treatment or placebo (11 studies) with a Peto Odds ratio (POR) at 0.32 (95% CI 0.20-0.53). Unfractionated heparin and low molecular weight heparin (4 studies) were equally effective POR 1.01 (95% CI 0.67-1.52). The combination of graduated compression stockings and LMWH is better than LMWH alone (2 studies) with a POR at 4.17 (95% CI 1.37-12.70). CONCLUSION: The optimal thromboprophylaxis in colorectal surgery is the combination of graduated compression stockings and low-dose unfractionated heparin or low molecular weight heparin.

Anticoagulants↗

TNM classification of genitourinary tumours 1987--position of the EORTC Genitourinary Group.

This report analyses the changes in the classification of the genitourinary tumours introduced by the 1987 edition of the TNM system. Criticism and suggestions for improvement are given. These are based on the extensive experience of the EORTC GU Group with clinical trial work particularly the identification of prognostic factors, on their success in reaching international consensus on tumour classification, and on information from the literature. Many of the changes introduced in the 1987 system are not considered to be strictly necessary. These include the introduction of the new additional descriptors, including "C" and "R", the changes in the T classification of prostatic and renal cancer, and the introduction of uniform N categories for all tumours and other features. We regret the omission of minimal requirements, the omission of the V classification for macroscopic or microscopic vascular invasion, the changes in the T categories of carcinoma of the bladder and the introduction of stage groupings for all urological tumours. Some of these changes are considered unacceptable. The attitude of the EORTC GU Group toward the use of the new TNM classification is indicated in detail.

Female↗

Annotation: The similarities and differences between autistic disorder and Asperger's disorder: a review of the empirical evidence.

BACKGROUND: The ongoing controversy over the distinction between autistic disorder and Asperger's disorder is important to resolve because of the implications regarding an understanding of the aetiology and prognosis, and the diagnostic and clinical practices relating to these conditions. This paper provides a critical evaluation of current published research evidence. METHOD: Databases, such as PsychINFO and Medline, as well as book chapters, reference lists from relevant articles, and recent editions of key journals were searched for all relevant studies (until 2002) which incorporated participants diagnosed with high-functioning autism and Asperger's disorder using either cluster analysis or comparative approaches to examine similarities and differences between these groups. Keywords used in the searches included autistic disorder, Asperger's disorder, autism, high-functioning autism, and pervasive developmental disorder. RESULTS: On the basis of the available evidence, there seem to be few qualitative differences between autistic disorder and Asperger's disorder. CONCLUSION: There is currently insufficient evidence to establish the validity of Asperger's disorder as a syndrome distinct from high-functioning autism. The findings are consistent with the view that these disorders belong on an autism spectrum.

Asperger Syndrome↗

Epilepsy Care in the World: results of an ILAE/IBE/WHO Global Campaign Against Epilepsy survey.

PURPOSE: Information about existing resources available within the countries to tackle the huge medical, social, and economic burden caused by epilepsy is lacking. To fill this information gap, a survey of country resources available for epilepsy care was conducted within the framework of the ILAE/IBE/WHO Global Campaign Against Epilepsy. METHODS: The study represents a major collaborative effort involving the World Health Organization (WHO), the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE). RESULTS: Data were collected from 160 countries representing 97.5% of the world population. The information included availability, role, and involvement of professional and patient associations for epilepsy, epilepsy treatment and services including antiepileptic drugs, human resources involved in epilepsy care, teaching in epileptology, disability benefits, and problems encountered by people with epilepsy and health professionals involved in epilepsy care. The data confirm that epilepsy care is grossly inadequate compared with the needs in most countries. In addition, large inequities exist across regions and income groups of countries, with low-income countries having extremely meager resources. Complete results of this survey can be found in the Atlas: Epilepsy Care in the World. CONCLUSIONS: The data reinforce the need for urgent, substantial, and systematic action to enhance resources for epilepsy care, especially in low-income countries.

Cross-Cultural Comparison↗

Polymedicine: known and unknown drug interactions.

Despite more than 15 years of extensive scrutiny, adverse drug interactions, especially in the elderly, remain a problem for the clinician. A two-pronged approach is suggested to contend with drug interactions: detection or avoidance of known drug interactions; and predictions and characterization of hitherto unknown interactions. The former approach is aided by critical reference sources on the subject and the use of drug interaction screening aids such as drug interactions alert lists or rotating drug discs. Computers are becoming increasingly important not only for the detection of potential drug interactions but also for the delineation of drug therapy options. Ultimately, computers can be used to predict interactions on the basis of physiochemical, pharmacokinetic, and pharmacodynamic data. For the present, extensive epidemiologic research programs can serve to ferret out interactions. Limited accessibility to such program data bases mandates a high index of suspicion in prepared and well-informed observers if the drug interaction problem is to be dealt with.

Documentation↗

Quality of poisoning management advice in the Monthly Index of Medical Specialties Annual.

BACKGROUND: The Monthly Index of Medical Specialties (MIMS) contains Therapeutic Goods Administration-approved product information supplied by manufacturers. It is widely used by health-care professionals but is not specifically designed as a toxicology reference. OBJECTIVES: To determine how widespread the use of MIMS is as a toxicology reference. To evaluate the quality of poisoning management advice it contains. METHODS: First, a survey of 500 consecutive calls to the NSW Poison Information Centre (PIC) was undertaken asking health-care workers which toxicology references were consulted prior to calling and which references they would use if the PIC were not available. Second, a consensus opinion for poisoning management was obtained, for 25 medications which are either commonly involved in poisoning or potentially life-threatening in overdose, by review of 5 current toxicology references for contraindicated treatments, ineffective treatments and specific recommended treatments and antidotes. MIMS poisoning management advice was then compared with this toxicology consensus opinion. RESULTS: In total, 276 doctors and 222 nurses were surveyed. Prior to calling the PIC 22.8% of doctors and 6.8% of nurses consulted MIMS. In total, 25.7% of doctors and 39.6% nurses stated they would use the MIMS for poisoning management advice if the PIC were not available. For the 25 drugs assessed, 14 contained inaccurate poisoning management: 1 recommended ineffective treatments and 14 omitted specific treatments or antidotes. CONCLUSION: The MIMS is often used as a toxicology reference by physicians prior to calling the PIC. It contains a number of significant inaccuracies pertaining to management of poisonings and should not be used as a primary reference for poisoning advice.

Australia↗

Evaluation of cancer-preventive agents and strategies a new program at the International Agency for Research on Cancer.

About five years ago, the International Agency for Research on Cancer (IARC) initiated a new program, IARC Handbooks of Cancer Prevention, aimed at evaluating the evidence base for the cancer-preventive activity of various agents and strategies. To date (2001) 5 volumes have been published--1. Non-steroidalAnti-inflammatory Drugs, 2. Carotenoids, 3. Vitamin A, 4. Retinoids, and 5. Sunscreens--and volume 6 (Weight Control and Physical Activity) is in press. Future volumes will include evaluations of breast cancer screening (vol. 7) and fruits and vegetables (vol. 8).

Anticarcinogenic Agents↗

Structure and function of a middle-sized accident department.

An account of the working of a middle-sized accident department is given, based on the study of nearly 33,000 attendance records. The work load, management, and staffing as it is actually organized is briefly described. The effectiveness of the service given is bedevilled by certain features of the N.H.S.-in particular, the deplorable conditions of employment of staff in casualty departments.

Accidents↗