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How accurate is size and distance perception for very far terrestrial objects? Function and causality.

This study investigated absolute estimation of size and distance for natural and artificial objects at viewing distances of 1.1-15.3 km (Experiments 1 and 2) and 0.4-5.0 m (Experiment 3). The main results were that, regardless of distance range, size and distance estimates (S' and D') were related to objective size and distance (S and D), respectively, by a power function with an exponent of unity, but great individual differences in exponent were obtained for the far objects. The ratio S'/D' was reasonably represented by S'/D' = K theta n and S'/D' = tan(a theta +b), rather than S'/D' = tan theta, where theta is the visual angle. Partial correlations were obtained to examine whether (1) apparent size is determined by taking apparent distance into account or (2) both apparent size and apparent distance are determined directly by external stimuli. The combined data for the far objects and the data for the close objects showed that there were high correlations between S and S' and between D and D' and a low correlation between D' and S'. The data of Experiment 2 showed that both D' and S' were highly correlated with S, D, and theta, and there was a high positive correlation between D' and S'. It was suggested that the direct-perception model is valid under some situations, but the taking-into-account model is not supported in any set of data.

Distance Perception↗

Distance perception as a function of photographic area of view.

Distance perception of depicted objects was examined as a function of photographic area of view. Subjects viewed slides of natural outdoor scenes and directly estimated the distances to specified objects. Area of view was manipulated by means of photographing each scene with lenses of five different focal lengths: 135, 80, 48, 28, and 17 mm. Distance perception along the pictorial depth plane was systematically transformed through changing the photographic area of view: the shorter the focal length of the camera lens, the wider the area of view, and the greater the perceived distance. Linear functions for each subject's distance judgments revealed a very high goodness of fit. Both the y-intercepts and the slopes increased as focal length decreased. The increasing y-intercepts suggest that viewers place themselves farther away from the depicted scene as focal length decreases, compensating for the advancing proximal edge. The increasing slopes suggest that distance information throughout the pictorial depth plane appears to change with focal length. The subjects also made direct judgments of foreground truncation, revealing that foreground truncation decreased as focal length decreased, but that this decrease did not account for the considerable expansion in distance perception.

Adult↗

Haptic perception of object distance in a single-strand vibratory web.

Can humans, like other animals, perceive distance by mechanical vibrations transmitted in a solid medium? In seven experiments, subjects perceived the distances from the hand of occluded metal disks attached to a taut nylon strand. Mechanical waves were initiated at the hand by the subject or at the disk by the experimenter. The results of Experiments 1 and 2 showed that perceived distance was linearly dependent on object distance with or without practice. The results of Experiments 3 and 4 revealed an inverse dependency of perceived distance on strand tension. In Experiment 5, a constant difference in perceived distance between vertical and horizontal strand manipulations was found. The results of Experiments 6 and 7 showed that distance was perceptible when the mechanical wave was not initiated by the subject. The informational basis for this haptic spatial ability was sought in the dynamics expressed by the one-dimensional wave equation, specifically, in the constants relating strand forces to strand motions.

Adult↗

The logic of misperceived distance (or location) theories of the Poggendorff illusion.

For the Poggendorff display (transversal interrupted by parallel lines), the typical distance-misperception theory postulates that a particular linear distance extending across the empty space between parallels is underestimated; examples are the intertransversal slant distance defined by the closest ends of the transversal segments (a "wings-in Müller-Lyer like" underestimation) or the perpendicular distance between parallels (parallels "attract"). Distance misperception by itself, however, can neither establish that perceived transversal misalignment exists for a Poggendorff display nor specify the perceived-location condition(s) that will produce perceptual collinearity. The perceptual displacement vector is introduced as a means of specifying fully the perceptual mislocation (displacement) of one transversal segment with respect to the other. Given this vector information (direction as well as distance), the logical soundness of theories postulating distance or location misperception were evaluated, and they were compared on the basis of extant data. Such vector information can be used to evaluate other classes of theories as well.

Distance Perception↗

Meeting the challenge of developing courses for distance delivery: two different models for course development.

Nursing education is increasingly challenged to convert traditional course offerings to distance delivery modalities to accommodate practicing RNs who wish to pursue continuing education. There is a lack of understanding regarding the experiences of faculty and staff from other departments within the university in the development of distance education courses. The purpose of this descriptive study was to uncover the experiences of nursing faculty and members of a university support unit involved in interdisciplinary development of distance delivery courses. Interviews were conducted with 11 participants. Two organizational models were identified. Other issues that emerged in the development of distance delivery courses were: faculty ownership of distance courses; workload implications for faculty; clinical practice by distance; and faculty expertise in new technologies. Implications for incorporating the challenges facing nursing faculty in the 21st century in the development of distance delivery courses are discussed.

Education, Distance↗

Vestibular capture of the perceived distance of passive linear self motion.

The relative role of visual and vestibular cues in determining the perceived distance of passive, linear self motion were assessed. Seventeen subjects were given cues to constant acceleration motion: either optic flow, physical motion in the dark or combinations of visual and physical motion. Subjects indicated when they perceived they had traversed a distance that had been previously indicated either visually or physically. The perceived distance of motion evoked by optic flow was accurate relative to a visual target but was perceptually equivalent to a shorter physical motion. The perceived distance of physical motion in the dark was accurate relative to a previously presented physical motion but was perceptually equivalent to a much longer visually presented distance. The perceived distance of self-motion when both visual and physical cues were present was perceptually equivalent to the physical motion experienced and not the simultaneous visual motion even when the target was presented visually. We describe this dominance of the physical cues in determining the perceived distance of self motion as "vestibular capture".

Adult↗

Longitudinal analysis of student performance in a dental hygiene distance education program.

The purpose of the study was to determine if learners who receive face-to-face instruction in an educational program performed statistically better on established benchmark assessments (GPA, course averages, and NBDHE) than learners at a distance from the didactic course instructor. A comparative, quasi-experimental, ex-post facto study was conducted. The treatment variable was program type: face-to-face vs. distance. The performance of five consecutive classes was analyzed, from 1997 to 2001. These five classes consisted of 221 learners, 105 of them at the host site and 115 using distance learning. The experimental groups were divided based upon location--host or cooperating college (distance) site learners. Study results identified no significant difference between host and distance learner performance for the entire educational program. The use of interactive television (ITV) for delivery of an educational program using distance education technology provided acceptable results in learner didactic performance. Learners at both the host and cooperating college (distance) sites performed equally well. The results were used to document program outcomes.

Analysis of Variance↗

Errors in distance appreciation and binocular night vision.

Studying binocular vergence in relation to luminance levels, we isolated two types of behaviour which may explain differences in distance appreciation: 1. Underestimation of distances in subjects with overconvergence in darkness. 2. Overestimation of distances in subjects with underconvergence in darkness. Progression towards the limiting value of convergence varies from one individual to another for each mesopic and scotopic luminance level and for different experimental conditions: variable discrepancy between the observation distance and the tonic vergence distance; accommodative or fusional stimuli at varying degrees of eccentricity; mobile stimuli in the observer's peripheral field. The study of bipartition in depth of a given interval for different observation distances confirms the existence of two major categories of individuals. Over- or underestimation of the nearer subjective half correlates to the binocular dark convergence capacity of each individual. These findings may explain errors in distance appreciation for road users in night vision.

Convergence, Ocular↗

Effects of stimulus distance on measurements of dark convergence.

Dark convergence is often measured psychophysically by aligning two dichoptic stimuli, which are briefly flashed in a dark surround. In the present study, the effect of different stimulus parameters on dark convergence measurements was investigated. Chief among these was the effect of viewing distance (50, 100 and 500 cm) of the stimulus. Measured dark convergence was biased towards the actual viewing distance of the stimuli; this effect was stronger with bar stimuli than with point-and-line stimuli. Measured dark convergence depended on the viewing distance to a lesser extent if bar stimuli were observed through pin-holes (open accommodative feedback loop). The subject's knowledge of the viewing distance had a small but significant effect; the size of the nonius bars had none. To reduce artefacts due to the stimulus distance on psychophysical measurement of dark convergence, point-and-line stimuli should be used at a viewing distance of about 1 m. In this case, the effect of stimulus distance can be about 0.25 meter angle (ma), averaged over subjects, but it may be as large as 0.5 ms in some individuals.

Adolescent↗

Relationship between visual acuity and observation distance.

The visual acuities of 17 young emmetropes and corrected ametropes were measured over the range of 7.5-0.19 m using a Bailey-Lovie chart. Accommodation stimulus-response measures were also taken over this range using retinoscopy to establish whether variations in visual acuity with observation distance could be attributed to accommodation behaviour. Tonic accommodation was recorded using the Canon R1 autorefractor and was compared with visual acuity and stimulus-response results. In general, visual acuity was found to be dependent on stimulus distance, being significantly reduced for most observers for the closest targets. There were three categories of observer performance for visual acuity as a function of observation distance; one group showing no change in visual acuity with distance, a second showing a flat function for distances 7.55-0.5 m, and then a decrease in visual acuity for shorter distances; and a third category that showed a maximum visual acuity in the 1.2-1.6 m region. This behaviour was unrelated to individual stimulus-response characteristics and there was no significant relationship between tonic accommodation and the distance where acuity was best for the third category observers.

Accommodation, Ocular↗

Comparing measures of travel distances in primates: methodological considerations and socioecological implications.

Travel costs can influence numerous aspects of the lives of primates, including net energy balance (and therefore reproductive success of females) and maximum group size. Despite their potential impact, there has been no systematic comparison of different measures of travel distance. We compared three measures of travel distance in 30 min (actual distance of individuals, straight-line distance of individuals, and straight-line distance of groups) and their ratios in a small group and a large group of vervet monkeys (Cercopithecus aethiops) and between the large group of vervets and a group of patas monkeys (Erythrocebus patas) of roughly similar size. The large group of vervets traveled farther than the small group regardless of the measure used, but the ratios of the different measures were not significantly different between those groups. Patas monkeys traveled significantly farther than the large group of vervets regardless of the measure used. In both vervets and patas, straight-line distances of individuals (ISLD) and groups (GSLD) underestimated actual distances traveled by individuals (IAD), but the degree to which they did so differed between species. IAD is more accurate than the other two measures and is preferred for studies of energetics and individual reproductive success, although ISLD or GSLD may be substituted when the ratios of IAD/ISLD or IAD/GSLD do not differ between groups or species. The ratio of IAD/ISLD was larger in vervets than in patas, suggesting that individual vervets meander more over short periods of time than patas. The ratio of ISLD/GSLD was larger in patas than in vervets, suggesting that patas move at angles or across the group's center-of-mass whereas vervets move more consistently along with others in their group. This has implications for the formation of spatial subgroups and alliances within groups.

Animals↗

The sampling properties of some distance geometry algorithms applied to unconstrained polypeptide chains: a study of 1830 independently computed conformations.

In this paper we study the statistical geometry of ensembles of poly (L-alanine) conformations computed by several different distance geometry algorithms. Since basic theory only permits us to predict the statistical properties of such ensembles a priori when the distance constraints have a very simple form, the only constraints used for these calculations are those necessary to obtain reasonable bond lengths and angles, together with a lack of short- and long-range atomic overlaps. The geometric properties studied include the squared end-to-end distance and radius of gyration of the computed conformations, in addition to the usual rms coordinate and phi/psi angle deviations among these conformations. The distance geometry algorithms evaluated include several variations of the well-known embed algorithm, together with optimizations of the torsion angles using the ellipsoid and variable target function algorithms. The conclusions may be summarized as follows: First, the distribution with which the trial distances are chosen in most implementations of the embed algorithm is not appropriate when no long-range upper bounds on the distances are present, because it leads to unjustifiably expanded conformations. Second, chosing the trial distances independently of one another leads to a lack of variation in the degree of expansion, which in turn produces a relatively low rms square coordinate difference among the members of the ensemble. Third, when short-range steric constraints are present, torsion angle optimizations that start from conformations obtained by choosing their phi/psi angles randomly with a uniform distribution between -180 degrees and +180 degrees do not converge to conformations whose angles are uniformly distributed over the sterically allowed regions of the phi/psi plane. Finally, in an appendix we show how the sampling obtained with the embed algorithm can be substantially improved upon by the proper application of existing methodology.

Algorithms↗

Noninvasive evaluation of left ventricular performance by the shortest distance between mitral leaflets coaptation and interventricular septum at end-systole.

We attempted to evaluate left ventricular performance from the shortest distance between the mitral leaflets coaptation and the interventricular septum at end-systole (MVC-IVS distance). The subjects were 37 patients with coronary artery disease (CAD) with prior myocardial infarction (MI), 8 with CAD without prior MI, 22 with atypical chest pain, and 4 with aortic regurgitation. The MVC-IVS distance was measured on a two-dimensional echocardiogram obtained from the parasternal or apical long-axis view and frozen at end-systole. Left ventricular end-systolic volume and end-diastolic volume were obtained by left ventriculography, and the left ventricular ejection fraction was calculated. A significant positive correlation was observed between the MVC-IVS distance and the end-systolic volume (r = 0.83, p less than 0.001); a close correlation was observed between the MVC-IVS distance end-systolic volume and ejection fraction by monoexponential fitting (r = -0.91, p less than 0.001). Thus, a significant negative correlation was observed between the MVC-IVS distance and the left ventricular ejection fraction (LVEF) (r = -0.83, p less than 0.001). An MVC-IVS distance of greater than or equal to 30 mm suggests diagnosis of left ventricular dysfunction (LVEF less than 50%) with high sensitivity (94.4%) and specificity (90.6%), while a value less than 30 mm suggests that the left ventricular performance is likely to be normal. Thus one can easily evaluate the left ventricular performance noninvasively using this new index.

Adult↗

Influence of nozzle-to-skin distance in cryogen spray cooling for dermatologic laser surgery.

BACKGROUND AND OBJECTIVE: Cryogen sprays are used for cooling human skin during various laser treatments. Since characteristics of such sprays have not been completely understood, the optimal atomizing nozzle design and operating conditions for cooling human skin remain to be determined. MATERIALS AND METHODS: Two commercial cryogenic spray nozzles are characterized by imaging the sprays and the resulting areas on a substrate, as well as by measurements of the average spray droplet diameters, velocities, temperatures, and heat transfer coefficients at the cryogen-substrate interface; all as a function of distance from the nozzle tip. RESULTS: Size of spray cones and sprayed areas vary with distance and nozzle. Average droplet diameter and velocity increase with distance in the vicinity of the nozzle, slowly decreasing after a certain maximum is reached. Spray temperature decreases with distance due to the extraction of latent heat of vaporization. At larger distances, temperature increases due to complete evaporation of spray droplets. These three variables combined determine the heat transfer coefficient, which may also initially increase with distance, but eventually decreases as nozzles are moved far from the target. CONCLUSIONS: Sprayed areas and heat extraction efficiencies produced by current commercial nozzles may be significantly modified by varying the distance between the nozzle and the sprayed surface.

Cryotherapy↗

Optimal screening distance for ulnar neuropathy at the elbow.

Focal demyelinating lesions typically occur within a 1-cm segment of a nerve. In electrodiagnostic studies, measurements over longer distances decrease the chance of detecting such lesions, but measurements over shorter distances result in greater experimental error. Our objective was therefore to determine the optimal screening distance for ulnar neuropathy at the elbow (UNE) incorporating previously derived experimental errors for calculating nerve conduction velocity (NCV). Using a lesion model wherein prolongation of 0.4 ms was added to the expected latency of a 1-cm nerve segment, new NCVs were derived for distances between 1 and 10 cm for nerves normally conducting between 40 and 65 m/s. Lesion detection, or sensitivity, was defined as the likelihood of calculating a decrease of 10 m/s from the normal NCV while including the experimental error. Specificity was related to the likelihood of an inadvertent calculation of such a decrease in NCV in a segment without a lesion. Sensitivity and specificity were derived at multiple distances with varying NCVs. The total percentage error was the sum of the false-negative and false-positive percentages. The least total percentage error occurred at 3-4 cm, 4-6 cm, and 6-8 cm for nerves normally conducting at 40-50 m/s, 50-60 m/s, and 60-65 m/s, respectively. We conclude that the optimal distance for screening UNE, considering both sensitivity and specificity, is significantly less than 10 cm, perhaps as low as 4-6 cm; considering in addition the likely locations of focal lesions, the best distance is 6-8 cm.

Elbow↗

Near and distance vergence facility provides complementary clinical information in concussion-related convergence insufficiency.

PURPOSE: To compare near and distance vergence facility testing in adolescents and young adults with concussion-related convergence insufficiency and evaluate changes following office-based vergence/accommodative therapy (OBVAM). METHODS: This secondary analysis of the CONCUSS randomized clinical trial evaluated vergence facility at near (40&#xa0;cm) and distance (4&#xa0;m) using a 12&#x394; base out/3&#x394; base in prism flipper. Participants aged 11-25&#xa0;years with concussion-related convergence insufficiency were randomized to immediate or 6&#xa0;weeks delayed OBVAM. Vergence facility was assessed at baseline, outcome time 1 assessment (after 12 therapy sessions for the immediate group and 6&#xa0;weeks of watchful waiting for the delayed group), and outcome time 2 assessment (after both groups completed 16 therapy sessions). Agreement between near and distance vergence facility classifications was evaluated, and treatment-related changes were compared between groups. RESULTS: Of the 106 enrolled participants, 102 completed all study visits. At baseline, the near and distance vergence facility classifications demonstrated substantial discordance. Among 101 participants with both measures available, 49 demonstrated reduced distance vergence facility despite normal near vergence facility, whereas only two showed the opposite pattern (Cohen's &#x3ba;&#xa0;=&#xa0;0.12; p&#xa0;<&#xa0;0.0001). Vergence facility improved following therapy in both treatment groups, with larger early improvements in the immediate-treatment group. CONCLUSIONS: Near and distance vergence facility testing provided complementary rather than interchangeable clinical information in adolescents and young adults with concussion-related convergence insufficiency. Both measures improved following vergence/accommodative therapy, supporting consideration of both testing distances in clinical assessment.

Humans↗

Calculation of protein structures with ambiguous distance restraints. Automated assignment of ambiguous NOE crosspeaks and disulphide connectivities.

The distances derived from nuclear Overhauser effect (NOE) spectra are usually converted into three-dimensional structures by computer algorithms loosely termed distance geometry. To a varying degree, these methods require that the distance data is unambiguously assigned to pairs of atoms. Typically, however, there are many NOE crosspeaks that cannot be assigned without some knowledge of the structure. These crosspeaks have to be assigned in an iterative manner, using preliminary structures calculated from the unambiguous crosspeaks. In this paper, I present an alternative to this iterative approach. The ambiguity of an NOE crosspeak is correctly described in terms of the distances between all pairs of protons that may be involved. A simple restraining term is defined in terms of "ambiguous" distance restraints that can allow all possible assignments. A new minimization procedure based on simulated annealing is described that is capable of using highly ambiguous data for ab initio structure calculations. In particular, it is feasible to specify the restraint list directly in terms of the proton chemical shift assignment and the NOE peak table, without having assigned NOE crosspeaks to proton pairs. While the primary aim of this paper is determining the global fold of proteins from NMR data, similar strategies can be used for other types of ambiguous distance data. The application to one example, disulphide bridges with unknown connectivity, is described. Model NOE data were generated from the X-ray crystal structure of a small protein with known chemical shift assignments. Varying degrees of ambiguity in the data were assumed. The method obtained the correct polypeptide fold even when all distance restraints were ambiguous. Thus, the new approach may facilitate structure calculations with data derived from very overlapped spectra. It is also a step towards automating the calculation of structures from NMR data. This could prove especially valuable for data derived from three- and four-dimensional experiments. The approach may also prove useful for model building studies and tertiary structure prediction.

Disulfides↗

Characterization of long-range structure in the denatured state of staphylococcal nuclease. II. Distance restraints from paramagnetic relaxation and calculation of an ensemble of structures.

Structural analysis of delta131delta, a fragment model of the denatured state of staphylococcal nuclease, has been extended by obtaining long-range distance restraints between chain segments by paramagnetic relaxation enhancement. Fourteen unique PROXYL spin labels were introduced at sites that are solvent-exposed in the native state, and the resulting enhancements of T2 for the amide protons were measured by NMR spectroscopy. When these data were combined with either measured or estimated correlation times tau(c), the r(-6)-weighted, time and ensemble-averaged distance between the spin label and 30 to 60 amide protons could be calculated for each spin-labeled protein. On the basis of approximately 700 such loose distance restraints, ensembles of compatible structures were generated by a combined distance geometry/molecular dynamics approach. Because of the large uncertainty in the physical basis of these distance restraints, a number of calculations were carried out to establish the sensitivity of the calculated structures to systematic errors in these restraints. Overall, the structural features reflected in the paramagnetic relaxation data were robust; large variations in tau(c), in the bounds window of allowed distances, or in the number of restraint distances used had small effects on the general features common to all calculated structures. The global topology of this denatured form of staphylococcal nuclease, as described by an ensemble of conformations consistent with the data, is strikingly similar to that of the native state, the major difference being the segregation of two hydrophobic segments that form a beta hairpin in the native state. These findings suggest that the topology of a protein's fold is established in the denatured state in the absence of cooperative interactions involving tight packing or stable hydrogen bonding. Hydrophobic interactions alone may encode global topology.

Algorithms↗