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PubMedDate not supplied

Building a concept system to structure the contents of a decision support system--a grounded theory study of concepts in the knowledge domain of urinary tract infection.

In this study we present a concept system for the knowledge domain of urinary tract infections. The system was constructed using grounded theory methods, sampling from Swedish reference texts and patient records from consultations for urinary tract infections. The concept system is intended for use as an aid in the construction of a decision support system (DSS) for urinary tract infections, and as a search module in the mentioned DSS. In total 561 concepts were categorized in four major, and 58 subordinate categories. Relationships between the more important categories were developed, and the frequency of use of the most common concepts is presented. Using the presented categorical structure as domain model a prototype DSS for dipslide urine cultures has been developed.

Concept Formation↗
PubMed1989

Is the 'new' problem drinking concept of Heather & Robertson more useful in advancing our scientific knowledge than the 'old' disease concept?

Heather & Robertson maintain that the problem drinking concept represents a shift from a 'pre-scientific' to a 'scientific' paradigm within the field of alcohol studies. They consider that the usefulness of a concept can best be assessed in terms of the extent to which it facilitates the testing of hypotheses. The disease concept is of no value when judged in these terms due to the aetiological assumptions that are built into it. It is argued that since Heather & Robertson's 'new' approach incorporates a set of assumptions parallel to those of the disease concept it is equally tautological, and therefore does not represent the type of change in paradigm they propose.

Alcohol Drinking↗
PubMed1998

A comparison of traditional folk healing concepts with contemporary healing concepts.

Health professional interest in folk healing concepts as a means of complementing contemporary health care has flourished within recent years. Yet, despite this seemingly new area of study, many basic tenets of folk healing are consistent with principles ascribed to by modern health professionals. In this article, I elucidate several concepts shared by traditional folk healing systems and the contemporary health care system. These concepts include origin of illness, harmony and balance, motion, colors, symbols, and family and community involvement. The analysis of these concepts should enable nurses to have an advanced understanding of transcultural healing practices, as well as a heightened perspective on the shared dimensions of folk and contemporary health care systems.

Attitude to Health↗
PubMed1994

Conception rates. 2. Economic value of unit differences in percentages of sire conception rates.

The objectives of this research were to estimate 1) the annual increase in profitability and 2) the value of a unit of semen because of an increase of 1 in percentage of AI conception rate. Factors contributing to increased annual profit per cow included more milk production, less semen purchased, more calvings, and fewer reproductive cullings. With a 7% average monthly rate of decline in milk production between peak and end of lactation, $ .24/kg of milk net income over feed cost, $ 20/unit of semen, $ 150 per calving, and $ 400 per reproductive culling, values for increased annual profitability per cow ranged from $ .88 to $ 7.36, and increased value per unit of semen ranged from $ .60 to $ 5.01, when estrus detection and AI conception were each constrained to minima of 30% and maxima of 70%. Additional probability of concept was worth less at high rates of estrus detection and of AI conception. Within-herd variation can be attributed to differences between cows in milk production, asset value of the cow based on future expectations of milk production, and seasonal differences in milk price and rates of estrus detection. Further differences between herds can be expected as producers vary in discounting values for uncertainty of information. Therefore, generalizations from a single set of assumptions may be limited, and application of methods to specific cows and producers may be desirable.

Animals↗
PubMed2001

Effects of priming a bipolar attribute concept on dimension versus concept-specific accessibility of semantic memory.

In Experiment 1, participants received behavioral information about a person that could be interpreted as either honest or unkind. Priming a concept along 1 dimension (e.g., honesty) increased the likelihood of spontaneously describing the target along this dimension (i.e., as honest), regardless of whether the primed concept was directly applicable for interpreting the target's behavior ("honest") or was its bipolar opposite ("dishonest"). Experiment 2 replicated this finding in a different, product domain. It further demonstrated that when information is ambiguous, primed concepts can influence not only the dimension along which the target is described but also the value it is assigned along this dimension. The effect of priming in both experiments was reflected in participants' overall evaluations of the targets as well as in their spontaneous descriptions of it. Results were consistent with the assumption that bipolar attributes are associatively linked in memory but are stored as separate concepts rather than as values along a bipolar continuum.

Adult↗
PubMedDate not supplied

[Concepts of taxonomy and concepts of biodiversity: the problem of interaction].

There is, or there should be, an interaction between concepts of taxonomy and biodiversity. On the one hand, taxonomy develops some general and particular classificatory paradigms, which own diversity is to be taken into account to understand the nature of variety of natural kinds. On the other hand, analysis of the properties of biodiversity may put forward nontrivial problems for taxonomy that cannot be deduced directly from its own statements. From the point view of taxonomy, it is argued that the current concept of biodiversity based entirely on the species concept is deeply rooted in reductionistic view of nature. It is outdated epistemologically and should be replaced by the modern taxonomic concept of the hierarchical phylogenetic pattern. Operationally, the latter presumes a possibility for each species to be assigned a certain "phylogenetic weight", according to its phylogenetic uniqueness. From the point view of biodiversity, it is argued that the global biodiversity is a three component entity, as it includes, in addition to phylogenetic and ecological hierarchies, a biomorphic hierarchy, as well. This calls for taxonomy to elaborate the general principles of classification of biomorphs.

Classification↗
PubMed1977

[The concept of crisis. Historical roots and actual problems of the concept of crisis].

An analysis of the concept of crisis cannot ignore that it is often used in a highly suggestive way, nor should it neglect to look at its historical roots. The psychosocial crisis concept as it is used in psychiatry, psychotherapy, social work, etc. has two historic roots: one root lies in the medical-natural-sciences tradition; the other in the dramaturgical i.e. healing tradition, and they both flow together in the concept as commonly used. At present, there are numerous crisis definitions each of which emphasizes a different aspect. Greater precision, models and operational definitions are indispensable for exact research. Crisis precipitation, disposition (crisis proneness) of the system, environment and reaction of the system are discussed as separate aspects of a crisis. Finally, the innovative and constructive role is stressed which the crisis concept plays in research and practice.

Conflict, Psychological↗
PubMed1998

Biotransformation of 13-cis- and 9-cis-retinoic acid to all-trans-retinoic acid in rat conceptal homogenates. Evidence for catalysis by a conceptal isomerase.

The purpose of this study was to investigate whether and to what extent the steric isomerization of retinoic acids in conceptal tissues can be attributed to enzymatic catalysis in addition to thiol-dependent, nonenzymatic catalysis. Conversions of 13-cis-retinoic acid and 9-cis-retinoic acid to all-trans-retinoic acid catalyzed by cell-free preparations of conceptal rat tissues (gestational day 12.5) were investigated. Substrates and rat conceptal homogenates (RCH) were incubated in sodium phosphate buffer (0.1 M, pH 7.5) at 37 degrees C in the dark. Incubation mixtures were quantitatively analyzed by HPLC. In RCH-catalyzed reactions, conversions of 13-cis-retinoic acid or 9-cis-retinoic acid to all-trans-retinoic acid were very rapid, in comparison with uncatalyzed isomerization reactions (incubations without RCH). Comparisons of the rates of reactions catalyzed by freshly prepared vs. freshly prepared/dialyzed RCH showed no significant differences, indicating that small, suflhydryl-containing molecules such as reduced glutathione did not significantly contribute to the RCH-catalyzed reactions. Furthermore, at physiological concentrations (2.5-10 mM), reduced glutathione exhibited very low specific catalytic activities, indicating that nonenzymatic, sulfhydryl-dependent catalysis was not a major mechanism in catalyzing interconversions of retinoic acids in vivo. Enzymatic catalysis by RCH of the conversion of 13-cis-retinoic acid to all-trans-retinoic acid was further characterized by showing 1) substrate saturation kinetics, 2) reaction rates that increased proportionally with protein concentrations, and (3) much greater sensitivity of the reactions to heat inactivation and denaturation by urea, compared with nonenzymatic, glutathione-catalyzed reactions. Thus, isomerization of retinoids in conceptal tissues appeared to be under enzymatic control.

Alitretinoin↗
PubMed1996

A structure of self-conceptions and illness conceptions in rheumatoid arthritis (RA).

In 2 independent samples of RA patients, a large pool of self-reported illness experiences were statistically examined for content and structure of common types of self-conceptions and illness conceptions related to living with rheumatoid arthritis (RA). Multivariate analyses revealed 7 primary factors in both samples. Three constituted a positive continuum (fighting spirit, acceptance, revaluation), and 3 a negative (deprivation of life values, protest, reserved). The 7th factor (denial) was weaker and conceptually intermediate. The obtained factors contained many items similar to those in other established psychological instruments used in research on RA, but showed stronger relations to subjective well-being (mood) than any one of these. Disease indicators correlated only weakly with RA self-conceptions (RASC) and mood. The RASC factors appear to more broadly reflect different facets of positive and negative ways of individual experience of living with RA than other published instruments. They were tentatively interpreted as RA-specific expressions of dispositions towards positive and negative affect, respectively.

Activities of Daily Living↗
PubMed1984

Structural dimensions in aged self-concept: a Tennessee Self Concept study.

Structural aspects of self-concept in old age measured by the Tennessee Self Concept Scale (Fitts, 1965) were examined in an aged (means = 79.57, SD = 5.17 years) community sample (n = 82) using multivariate techniques. Three robust factorial dimensions emerged from a principal components analysis: self-acceptance; doubt resolution/defensiveness; and conflict integration. The importance of defensiveness in aged self-concept was highlighted.

Aged↗
PubMed1988

[The effect of social feedback on receiver's self-concept change: an examination of the role of receiver's perception on sender's self-concept].

Cognitive processes for feedback information on self-concept as influenced by the receiver's perception of the sender's trait were examined in 40 male and female undergraduates. Subjects in the consistent and inconsistent feedback situations received information consistent and inconsistent with their initial self-rating of a trait, respectively. The sender (confederate) had a higher or lower scale score for the same trait than the subjects. Subsequently, subjects did final self-rating. Inconsistent feedback produced self-concept changes no more than consistent feedback only when the sender had a higher trait tendency than the subjects. This finding suggests: (1) only in the inconsistent feedback situation, the receiver sets out to search cause of feedback; (2) whether or not the receiver changes one's self-concept depends on causal attribution of inconsistent feedback; and (3) the direction of causal attribution is influenced by the receiver's consideration of the sender's trait tendency.

Adult↗
PubMed1999

[Analysis of dental students' knowledge and concepts in oral health: evaluation by concept maps].

This study sought to analyze senior dental students' cognitive structure concerning the topic of "enamel", which is fundamentally important for understanding oral health, since it offers basic scientific concepts for clinical and preventive practices and is the main subject of several courses during dentistry training. The strategy used to analyze students' cognitive structures was Novak's Concept Maps, based on Ausubel's Meaningful Learning theory. Analysis of students' maps allowed for a study of students' cognitive structure and concepts concerning oral health. It also fostered a diagnosis of students' knowledge in several important aspects of scientific and professional training. The results highlighted the need for rethinking the teaching/learning process in dentistry training.

Concept Formation↗
PubMed1976

Beard's concept of neurasthenia and Freud's concept of the actual neuroses.

Beard's concept of neurasthenia and Freud's concept of the actual neuroses are described and evaluated critically. Despite differences in the content of their theories, especially in the role of sexual factors and sexual mechanisms, there are important formal and logical similarities. Both Beard and Freud incorrectly identified the causes of the neuroses being studied; both used inadequate methods of assessing the strengths of the causal factors; and the central theoretical concepts of both were equally vacuous. Freud adopted the same method of study as did Beard, but does not seem to have been influenced directly by him.

Austria↗
PubMed1997

Cellular and molecular neurosurgery: pathways from concept to reality--part I: target disorders and concept approaches to gene therapy of the central nervous system.

Recent advances in cellular and molecular biology and better understanding of genetic and biochemical bases of different central nervous system (CNS) disorders have made gene therapy of the CNS a realistic goal. Concept approaches for gene therapy of CNS disorders are reviewed and include the following: 1) gene replacement with a single normal allele to correct the inherited global neurodegenerative disorders, such as enzyme deficiencies; 2) brain repair to restore the function of a particular subset of cells that were lost because of a neurodegenerative process; 3) gene therapy of brain tumors; and 4) gene therapy of stroke. Techniques of viral vector-mediated CNS transfer of a therapeutic gene, transplantation of genetically modified cells, fetal embryonic implantation and/or implantation of genetically engineered neural progenitor cells, and production of a specific enzyme, neurotransmitter, and/or growth factor are discussed with respect to the therapeutic potential for global and localized CNS neurodegenerative disorders and stroke. Transfection of the CNS tumor cells with the drug susceptibility ("suicide") gene and/or "toxic" gene and antisense strategies and a concept of adoptive immunotherapy of brain tumors are also discussed. Other approaches, such as transfer of drug-resistant genes and monoclonal antibody gene transfer, are briefly discussed. In addition to summarizing current principles of gene therapy for several groups of CNS disorders, the issues that remain to be resolved in clinical reality, such as delivery of the genetic material and regulation of the cellular expression of the transgene, and the negatives associated with the concepts of gene therapy, such as transient gene expression, toxicity of viral proteins, drawbacks of antisense therapy, and the problem of immune response to the transfected protein, have been also identified.

Animals↗
PubMed1975

[The polarity concept in leprosy: polar types, polar system, polar concept, dichotomy].

The author presents his priority of the polar concept in leprosy, and briefly reviews what he calls the history of an idea. The polar concept was first presented in February-May 1938, and was to receive full recognition from the Havana's Committee on Nomeclature and published in the Annals of the 5th International Congress of Leprosy (April 1948). In recent years many points brought by immunopathology focused the humoral immunity at the level of the immuno-negative L pole, in clear-cut opposition to the cell-mediated immunity present in the immuno-positif T pole. Polar concept thus receiving a remarkable physio-pathological support to the views once expressed by the author.

Humans↗
PubMed1999

Concept formation and concept shifting in frontal lesion and Parkinson's disease patients assessed with the California Card Sorting Test.

Concept formation and shifting abilities of 17 frontal lesion (FL) and 8 Parkinson's disease (PD) patients were assessed with the California Card Sorting Test. FL patients demonstrated a significantly greater number of perseverative responses and deficits in strategy planning, strategy initiation, and concept formation and did not benefit from abstract cues in comparison with their matched normal control (NC) participants. PD patients also demonstrated an increased number of perseverative responses under selected conditions in comparison with their matched NCs, but their ability to explain their sorts, to extract and express the sorting principles, and to sort with the help of abstract and concrete cues depended on their general cognitive status.

Aged↗
PubMed1995

Matching words to concepts in two languages: a test of the concept mediation model of bilingual representation.

A categorization paradigm was used to investigate the relations between lexical and conceptual connections in bilingual memory. Fifty-one more fluent and less fluent English-French bilinguals viewed category names (e.g., vegetable) and then decided whether a target word (e.g., peas) was a member of that category. The category names and target words appeared in both English and French across experimental conditions. Because category matching requires access to conceptual memory, only relatively fluent bilinguals, who are able to directly access meaning for their second language, were expected to be able to use category information across languages. The performance of less-fluent bilinguals was expected to reflect reliance on lexical-level connections between languages, requiring translation of second-language words. The results provided evidence for concept mediation by more-fluent bilinguals, because categorization latencies were independent of the language of the category name. However, the performance of less-fluent bilinguals indicated that they did not follow a simple lexical translation strategy. Instead, these subjects were faster at categorizing words in both languages when the language of the category name matched the language of the target word, suggesting that they were able to access limited conceptual information from the second language. A model of the development of concept mediation during second language acquisition is described.

Adult↗
PubMed1998

[The conception of human subjectivity vis-a-vis the basic concepts of theoretical and practical medicine].

Conceptions of human subjectivity have throughout ages had an impact on the defining the subject-matter of theoretical and practical research in the area of medicine. They have influenced the way the patient was perceived in relation to the social and natural environments, and they have also provided the basis upon which diagnostic and therapeutic conceptions could be constructed. The author presents her own proposals for defining such notions as medical theory, medical doctrine and school of medicine. The present study gives an account of the changes in the research agenda of medicine in particular historical epochs in conjunction with the changes in defining human subjectivity as the subject-matter of its research.

History, Early Modern 1451-1600↗