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Anatomy of greater palatine foramen and canal and pterygopalatine fossa in Thais: considerations for maxillary nerve block.

This study aims to investigate the anatomy of the greater palatine foramen (GPF), greater palatine canal (GPC) and pterygopalatine fossa (PPF) with special reference to the blockage of the maxillary nerve. A correlation between the length of GPC and PPF and the heights of the orbit and the maxilla was also studied using simple linear regression analysis. The morphology of the GPF, GPC and PPF as well as heights of the orbit and the maxilla were assessed in 105 Thai skulls. The thickness of the mucosa over the GPF was also measured from the dissection of 55 cadavers. The results showed that most GPF appeared as an oval foramen located at the palatal aspect of the upper third molar. The GPF was 16.2+/-1.3 mm lateral to the median sagittal plane of the hard palate, 2.1+/-1.3 mm anterior to the posterior border of the hard palate and 5.1+/-1.3 mm from the greatest concavity of the distolateral margin of the hard palate. The mean length of GPC and PPF was 29.7+/-4.2 mm. The mean angles of the GPC in relation to the hard palate and the vertical plane were 57.9+/-5.8 degrees and 6.7+/-5.2 degrees , respectively. In attempting to insert a needle to reach the foramen rotundum through the GPF, 31.7% passed into the orbit while 8.7% passed into the brain. The mean thickness of the mucosa over GPF was 6.7+/-2.3 mm. Two models for estimating the depth of needle injection in maxillary nerve block have been developed as follows: Length of GPC and PPF=19.038+0.314 (orbital height) and length of GPC and PPF=21.204+0.187 (maxillary height). The calculated length combined with the mucosal thickness was the estimated depth of needle injection. In conclusion, our results concerning the GPF, GPC and PPF will provide the useful reference for clinicians to anesthetize the maxillary nerve with a greater degree of success.

Adolescent↗

Maxillary nerve involvement in bacterial endocarditis.

A case of right maxillary nerve paresthesia during an active phase of bacterial endocarditis probably due to embolic occlusion of the nerve's vascular supply is reported. The authors suggest that infective endocarditis be considered as a rare but potential cause of unexplained trigeminal nerve branch lesions, and that such lesions be sought in cases of established endocarditis.

Embolism↗

Maxillary nerve block: a case report and review of the intraoral technique.

Maxillary nerve blockade is not commonly used by general practitioners due to a lack of experience with the techniques involved and the fear of iatrogenic damage. Nevertheless, it represents an excellent method of producing profound anesthesia in the maxilla, with definite indications in selected instances. The anatomy and techniques associated with the maxillary block, as well as the indications, contraindications and complications are reviewed, and the use of the greater palatine foramen approach to treat a patient with a facial abscess is described.

Anesthesia, Dental↗

[Effect of histamine on the action potential of the maxillary nerve in rabbits].

The significant enhancement of action potential as recorded from rabbit maxillary nerve with topically applied 1.0 mmol/L histamine on the nasal mucosa was completely blocked by pretreatment with diphenhydramine (H1 antagonist) but not with cimetidine (H2 antagonist). This fact gives new support to the concept that histamine exerts its pathological effect on nasal mucosa at least partly via an afferent nervous pathway of the trigeminal nerve.

Action Potentials↗

Choristoma of the intracranial maxillary nerve in a child. Case report.

This report describes what the authors believe to be the first reported case of choristoma of the intracranial maxillary nerve. This 12-year-old girl presented with a 5-year history of severe isolated left-sided trigeminal neuralgia. Computerized tomography and magnetic resonance imaging revealed a mass below the anterior portion of the left cavernous sinus, enlarging the foramen rotundum. Total resection was achieved via a pterional extradural approach. Histological examination revealed a choristoma composed of smooth-muscle fibers. The histogenesis of these tumors when they develop in a nerve remains unclear. They may represent abnormal migration or proliferation of neuroectodermal tissue in or close to a peripheral nerve. Total removal of these tumors should be attempted at initial diagnosis.

Actin Cytoskeleton↗

Maxillary nerve block via the greater palatine canal: new look at an old technique.

Although not widely used, maxillary nerve block via the greater palatine canal can be remarkably effective. This article is aimed at reviving its use by reviewing the indications, contraindications, and anatomy of the technique. A simplified guide to the technique is offered to place the technique within the armamentarium of the practicing dentist.

Anesthesia, Dental↗

Fibers of trigeminal mesencephalic neurons in the maxillary nerve of the rat.

Indirect Wallerian degeneration after sectioning the infraorbital nerve, and retrograde axonal transport following injection of horseradish peroxidase (HRP) into the maxillary nerve were studied in rats. These experiments showed the existence of primary trigeminal neurons in the pars caudalis of the ipsilateral trigeminal mesencephalic nucleus and in the supratrigeminal nucleus of Lorente de Nó. Such neurons were interpreted as being responsible for the sensitive innervation of the periodontal membrane.

Animals↗

Cation-binding sites in trigeminal ganglia and maxillary nerve: unusual reactivity of perikarya, stem axons and satellite cells.

We have used the cupric/ferrocyanide reaction to study cation-binding in trigeminal ganglia and maxillary nerve of adult rats. Unmyelinated axons did not react, whereas myelinated axons were stained at nodal, paranodal or cleft sites. At 'nodal' sites, metallic deposits were found in the axoplasm, along the axolemma, and at the extracellular interfaces of the paranodal myelin. At 'paranodal' sites, particles were concentrated in the paranodal axoplasm and in the intracellular spaces of the myelin loops. Most maxillary axons examined at successive sites had all nodal or all paranodal staining, but 13 of 51 had a mixture. In trigeminal ganglia there was no staining of perineurial sheath, endoneurial cells or mast cells. Satellite cells and their basal laminae were prominently stained, with those around small neurons more reactive than those of large neurons. Patches of neuronal membrane on cell bodies were stained, more often for small than large neurons. The axon hillock and proximal stem axon were not stained in some cases, but approximately half the neurons had staining of perikaryal cytoplasm at the axon hillock or a dense asymmetric band in the proximal stem axon. Strong intraaxonal staining was found at the junction between unmyelinated proximal and myelinated distal stem axon. In distal stem axons, staining was found at the first myelin segment and at each successively thicker myelin segment; staining was mostly weak and paranodal, with intensity proportional to myelin thickness. The T-junction between stem and main myelinated axon had nodal or paranodal patterns; unmyelinated T-junctions were not stained. The varied cation-binding patterns in trigeminal ganglia show unusual properties of satellite cells and important differences between stem and main axons. The results that the cell membrane of axon hillock and proximal stem regions of many sensory large and small neurons may have numerous sodium channels and could affect signal propagation.

Animals↗

Neurotropic melanoma of the face invading the maxillary nerve.

Neurotropic melanoma is a variant of desmoplastic melanoma which, in addition to a spindle-cell vertical component and fibrosis, exhibits a fascicular growth pattern and invades cutaneous nerves. Here we describe a neurotropic melanoma which arose in a small lentigo maligna melanoma and invaded the maxillary nerve for a distance of 5 cm. Ultrastructural features were similar to those of previously described neurotropic melanomas and tumor fascicles contained S-100 protein and neuron-specific enolase immunoreactivity.

Facial Neoplasms↗

Prevention of hypertension during trans-sphenoidal surgery--the effect of bilateral maxillary nerve block with local anaesthetics.

BACKGROUND: Severe cardiovascular responses are known to occur during trans-sphenoidal excision of the pituitary gland despite adequate depth of anaesthesia. This study was undertaken to evaluate the effects of bilateral maxillary nerve block with local anaesthetics on the cardiovascular responses to various stimuli during this procedure. METHODS: In a group of 32 patients, 5-10 ml of a mixture of bupivacaine 0.5% and lignocaine 2% (1:1) was injected in the pterygopalatine fossa after induction of general anaesthesia. Seven control group patients did not receive any nerve block. In all the patients, general anaesthesia was induced with thiopentone and maintained with nitrous oxide-oxygen, pentazocine, boluses of thiopentone and halothane. Pancuronium was used for neuromuscular blockade. RESULTS: In both the groups, maximum hypertension occurred on opening the blades of the bivalve nasal speculum. In the study group, hypertensive response was significantly less following nasal infiltration with adrenaline containing solution (10.26% increase vs. 23.08% in the control group, P < 0.05), nasal dissection (2.82% vs. 9.45%, P < 0.01) and on application of the nasal speculum (14.93% vs. 35.16%, P < 0.01). The effect on heart rate response was not significant. CONCLUSION: The described technique is a useful adjunct to general anaesthesia for suppressing the haemodynamic responses during trans-sphenoidal surgery.

Adult↗

[Approach to the maxillary sinus, the peterygopalatofossa for resecting maxillary nerve under the endoscopy].

OBJECTIVE: This paper presents a method for treating maxillary neuralgia, the second division of trigeminal nerve, in the weak aged. METHOD: Thirty-nine cases with forty trigeminal neuralgia were treated from 1996 to 2001. All patients were treated through the maxillary sinus, the peterygopalatofossa for resecting maxillary nerve with endoscopic surgery. RESULT: The pain of all patients was relieved after operation and no recurrence of neuralgia was occurred in more than 2-years follow-up. CONCLUSION: This method had the advantages of avoiding to operate craniotomy, no complications, performing easily and the ideal treatments remained.

Aged↗

Maxillary nerve block: the pterygopalitine canal approach.

Over the past few years, the dental industry has introduced a number of new local anesthetic delivery systems. Despite the advantages of many of these newer techniques, conventional needle and syringe procedures remain the cornerstone of local anesthesia for most dental practitioners. Most of these "tried and true" approaches are both popular and comfortable for the dentist since they are widely taught in undergraduate dental curriculum. There is one technique, however, that although relatively safe, effective and reliable, is not usually included in undergraduate dental programs. This technique, the maxillary nerve block via the pterygopalitine canal, provides the patient with a profound block of nerve V2 and allows the dentist the ability to perform procedures anywhere in the maxillary quadrant that has been anesthetized.

Anesthesia, Dental↗

Stable synchronized high-frequency signals from the main sensory and spinal nuclei of the pig activated by Abeta fibers of the maxillary nerve innervating the snout.

The primary somatosensory cortex of various species including man, monkey, pig and rat is capable of producing high-frequency signals in the 600 Hz range and above with very little latency jitter. We have recently observed such cortical signals for the trigeminal system of the swine. This study determined the projection of the maxillary nerve innervating the snout to the sensory trigeminal nuclear complex in the brain stem and stability of outputs of each nucleus receiving the projection. The snout stimulation activated large-caliber Abeta fibers in the trigeminal nerve with a mean velocity of 64.4+/-2.7 m/s (mean+/-1 S.E.M., six animals) comparable in velocity to the tooth pulp Abeta fibers (57.9+/-3.4 m/s) obtained from the same animals. These afferents activated the main sensory nucleus, and subnuclei oralis, interpolaris and caudalis of the spinal nucleus, as judged by evoked field potential maps superimposed on the histological maps of the trigeminal nuclei from the same animals. Inputs from these fast afferents arrived at all the four trigeminal nuclei almost simultaneously within a span of 0.7+/-0.2 ms (mean+/-1 S.D., seven animals). Evoked high-frequency signals were reproducible with a latency jitter of less than 0.2 ms during the first 4 ms of postsynaptic activity for each of main sensory and spinal nuclei. These results indicate that the snout stimulation activates fast-conducting peripheral afferents which project to all the sensory trigeminal nuclei and produces highly reproducible initial responses nearly simultaneously across the multiple trigeminal nuclei. These outputs from the trigeminal nuclei may play an important role in triggering the stable high-frequency signals in the cortex.

Action Potentials↗

[Anatomy of extraoral block anesthesia of the maxillary nerve (precoronoid approach)].

The authors measured with sliding-calliper of 0.01 mm of accuracy bi-zigio distance and the distance between the foramen rotundum and vertex of the angle formed by the anterior border of the coronoid process with the lower border of the zygomatic bone. The sample was 160 brazilian adults skulls (50% male and 50% female). Using the Pearson's correlation they found the following results: 1) The positive correlation was reasonably strong in male at the right side between the maximal width of the face and the ideal depth, to reach with an injection needle, the maxillary nerve in the pterigopalatine fossa. 2) The correlation was moderately positive in male sex at the left side and in female at both sides. The formula of the line of regression found was: [table: see text]

Adult↗

Developmental pattern of axonal pathways in the house shrew maxillary nerve.

The topographic patterns of peripheral receptors and effectors seem to contribute to the construction of the neuronal circuit in the central nervous system (CNS) in mammals. Many patterns replicating those of the periphery have been found in the CNS, and fasciculation has been regarded as having a central role in the pattern replication. The house shrew, Suncus murinus, is an excellent species in which to study this topic because it has a vibrissae system arranged in a single ordered fashion and extraordinarily well-developed trigeminal spinal tracts. Using immunostaining and retrograde-tracing techniques, we examined the developmental pattern of the maxillary nervous system in the house shrew. The results indicate that the basic pattern of axonal extension reiterates with a parallel arrangement throughout the course of development except at a site in the brainstem where the central processes bifurcate into ascending and descending branches. Dorsoventral inversion of the peripheral pattern in the spinal tract occurs with this dual-leveled bifurcation in association with the mediolaterally ordered entry of the central processes into the brainstem. The basic pattern of the central processes is established prior to the appearance of the vibrissae, indicating that the basic topographic pattern of the maxillary nerve is not related to the vibrissae system. The fasciculation pattern does not correspond to the overall layout of the arrays of vibrissae, and there are frequent exchanges of axons between fascicles both in the periphery and centrally. The parallel organization of the majority of the processes, together with the free exchange of processes between fascicles, suggests that these processes have an important role in the formation of the fasciculation and somatotopic patterns.

Age Factors↗

Risky anatomic variations of sphenoid sinus for surgery.

We searched for the surgically risky anatomic variations of sphenoid sinus and aimed to compare axial and coronal tomography in detection of these variations. Fifty-six paranasal tomography images (112 sides) were evaluated for coronal, axial and both coronal and axial images. Tomographic findings including bony septum extending to optic canal or internal carotid artery; protrusions and dehiscences of the walls of internal carotid artery, optic nerve, maxillary nerve and vidian nerve; extreme medial course of internal carotid artery; patterns of aeration of the anterior clinoid process; and Onodi cells were evaluated. The results were classified as "present, absent, suspicious-thin (only for dehiscence) or no-consensus". The results of each plane were compared with that of the result of the both planes together. Kappa coefficient and Chi-square tests were used to compare both planes. Twelve cadaveric dissections were performed to reveal the proximity of sphenoid sinus to surgically risky anatomic structures. Endoscopy was applied to five cadavers. 18 evaluations were classified as 'no-consensus'. We detected 34, 35, 34 and 40 protrusions of internal carotid artery, optic nerve, maxillary nerve, vidian nerve, respectively. Dehiscences were present in 6, 9, 4 and 8, and suspicious-thin in 8, 10, 16 and 25 in canals of internal carotid artery, optic nerve, maxillary nerve and vidian nerve, respectively. Bony septum to internal carotid artery and optic nerve was observed in 30 and 22 cases. We observed 9 extreme medial courses of internal carotid artery, 27 aerated clinoid process and 9 Onodi cells. Axial images were superior in detection of bony septum to internal carotid artery and Onodi cells; while the coronal images were more successful in detection of protrusion of optic nerve and vidian nerve, and dehiscense of maxillary nerve and vidian nerve (P<0.05). In cadaveric dissections, the septa were inserted into the bony covering of the carotid arteries in two sinuses (8.3%). Detailed preoperative analysis of the anatomy of the sphenoid sinus and its boundaries is crucial in facilitating entry to the pituitary fossa and reducing intraoperative complications. Coronal tomography more successfully detects the sphenoid sinus anatomic variations.

Adult↗