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[Precipitation reaction and hemagglutination-hemolysis reaction in tuberculosis. II. Hemagglutination-hemolysis reaction by Middlebrook-Dubos (author's transl)].

Sera of patients with pulmonary and extrapulmonary tuberculosis, of blood donors and cattle sera were researched in hemagglutination reaction, using untreated and papain-treated sheep erythrocytes, and in hemolysis reaction. 58% of patients with pulmonary tuberculosis and 23% of normal sera, reacted positive in at least one of the 3 reactions. 24 sera of 44 patients with extrapulmonary tuberculosis were found to be positive. The titer is important for diagnosis. In normal sera the highest titers were 1:64 in all reactions. Titers of 1:128 are to be considered as proof of tuberculosis. Considering the height of titers the hemagglutination-hemolysis reaction can also be used for diagnosis of tuberculosis in cattle.

Animals↗

[Post-transfusion hemolysis in premature infants. Apropos of 8 cases of post-transfusion hemolysis in premature infants].

Accidents related to blood transfusion have become rare in neonates, due to the application of very strict rules. The 8 reported cases of post-transfusion hemolysis occurred in prematures less than 32 weeks gestational age. Signs consisted of hemoglobinuria and/or severe jaundice. In some patients exchange-transfusion had to be performed. Immuno-hematologic, bacteriologic and technical investigations did not show the etiology of these accidents. No similar clinical reports were found in the literature. Some authors suggest a mechanical origin.

Erythroblastosis, Fetal↗

Kinetic studies on immune hemolysis. II. The reversibility of red cell-antibody combination and the resultant transfer of antibody from cell to cell during hemolysis.

The reversibility of the red cell-antibody combination has been demonstrated by means of experiments showing the transfer of antibody, either from red cell stromata to intact red cells, or from red cell to red cell. The extent of reversibility is variable with respect to different antisera. The transfer of antibody from stromata to intact red cells is not dependent upon the action of complement. Transfer of antibody can also take place after interaction of the stromata-antibody complex with complement. As a result, antibody molecules can perform hemolytic work over and over again, provided complement is available, and this leads to kinetic behavior of a catalytic character.

Antibodies↗