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MAST suits.

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Animals↗
PubMed1979

Modification of the normal postural changes in plasma renin activity by the application of positive pressure to the legs.

In six normal male subjects plasma renin activity (PRA) rose progressively on standing over a 2 hour period. PRA fell to basal levels after a further 2 hours of recumbency. The rate of rise of PRA on standing was largely abolised following the application of an anti-gravity ('G') suit. Continuous monitoring of blood pressure (BP) heart rate (HR) and packed cell volume (PCV) suggest that it is the fall in effective blood volume which elicits the stimuli to renin release during changes in posture.

Adult↗
PubMed1990

The development of the Australian anti-G suit.

Prof. Frank Cotton of Sydney University, Australia, designed the world's first successful gas-operated anti-G suit. Research commenced late in 1940, and a suit was designed with rubber sacs covered externally by inextensible material. The sacs automatically inflated when G forces increased during flying. Initially tested on a centrifuge specially built at Sydney University, and then flight-tested in a Hurricane, Kittyhawks, and Spitfires, the suit provided about 2 G protection. The Canadians had earlier developed a water-filled suit, which the RAF adopted, but comparative trials in 1944 by the Royal Air Force concluded that: "There is no doubt the Cotton Suit gives the best protection." By the time the Cotton Aerodynamic Anti-G Suit was operational, Japanese attacks on Darwin had virtually ceased, and the suit was never used in combat. However, the principle of gas-inflatable bladders is still used in the modern anti-G suit.

Australia↗
PubMed1978

The MAST suit in the treatment of cardiogenic shock.

Based on initial success using the medical antishock trouser (MAST) suit in treating 150 patients in traumatic, hypovolemic shock in the city of Bellingham and Whatcom County, Washington, at St. Luke's Hospital, the indications for its use have been expanded to include certain types of cardiogenic shock. The rationale was based on the frequent inability to differentiate hypo-, hyper-, and normovolemia in patients in cardiogenic shock and the need for a safe, reversible fluid challenge to differentiate these conditions. Changes in the condition of 14 patients in cardiogenic shock after application of the MAST suit were evaluated. Six patients responded with improved cardiac output and blood pressure. Four had no significant change in their condition and four became worse. In all patients whose condition was unchanged or worsened, the fluid challenge was reversed by deflating the suit. Based on these preliminary findings, it would seem that extended indications exist for using the MAST suit.

Aged↗