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Results for “Technology Transfer”

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At least 343 records · Page 19Linked to original sources
PubMed2003

Membrane technologies applied to textile wastewater treatment.

This paper describes the experimental results of a pilot-scale application of membrane technologies to textile wastewater advanced treatment, downstream of a biological activated sludge process, aimed at water reuse in textile technology processes. The chosen approach consisted of sand filtration as a pretreatment, a microfiltration (MF) or ultrafiltration (UF) membrane process, and a final separation treatment performed by means of a nanofiltration (NF) or a reverse osmosis (RO) membrane. An experimental study to compare spiral wound membranes, operating under pressure, to flat membranes, operating under vacuum was conducted. The technical results and a preliminary economic analysis indicate the possibility of technological transfer of the membrane technologies to an industrial scale for textile wastewater reclamation.

Journal Article↗
PubMed1998

From airports to care centers. Transferring information technology to support patient care reengineering.

PROBLEM: To improve communication among caregivers about the status of patients under their care. SOLUTION: Replacing manual white boards with electronic bed boards/inpatient databases, similar to airport display technology. RESULTS: Improved data quality from having patient data displayed in a standardized manner across care centers. KEYS TO SUCCESS: "We used a process redesign team, which focused on specific issues related to the processes used in providing patient care."

Computer Communication Networks↗
PubMed2002

Production of transmitochondrial mice.

With the advancement of various gene transfer technologies, the establishment of mitochondria transfer as a viable technique to genetically engineer mouse models paradoxically lagged behind other genetic technologies. The lack of demonstrable recombination in mtDNA necessitates different approaches to conventional transgenesis-based techniques. Initially, heteroplasmic mice were created to explore disease pathogenesis and mitochondrial dynamics in an in vivo system. Ultimately, transmitochondrial mouse models will be used to explore the role of the mitochondrial genome in human disease processes and in the development of novel human gene therapies. Here, we describe methodology to produce transmitochondrial mice (both homoplasmic and heteroplasmic models) harboring foreign mitochondrial genomes, using both embryo microinjection and embryonic stem (ES) cell-based approaches. Specific modeling and the procedures for mitochondrial transfer will be of considerable importance toward our understanding of discrete mitochondrial mutations, as well as lead to the development of novel strategies and therapies for human diseases influenced by mitochondrial DNA mutations.

Animals↗
PubMedDate not supplied

Progress with retroviral gene vectors.

Retroviral vectors have become a standard tool for gene transfer technology. Compared with other gene transfer systems, retroviral vectors have several advantages, including their ability to transduce a variety of cell types, to integrate efficiently into the genomic DNA of the recipient cells and to express the transduced gene at high levels. The relatively well understood biology of retroviruses has made possible the development of packaging cell lines which provide in trans all the viral proteins required for viral particle formation. The design of different types of packaging cells has evolved to reduce the possibility of helper virus production. The host range of retroviruses has been expanded by pseudotyping the vectors with heterologous viral glycoproteins and receptor-specific ligands. The development of lentivirus vectors has allowed efficient gene transfer to quiescent cells. This review describes different strategies adopted for developing vectors to be used in gene therapy applications.

Animals↗
PubMed2004

Preparing the next generation of scientists in translation research.

AIM: Four questions about translation research are considered in this article. (1) Why should there be concern about preparing nurse scientists for translation research? (2) Are current research-intensive doctoral programs in nursing preparing graduates for translation research? (3) Should targeted efforts be made to systematically prepare nurses in translation research? (4) What strategies would be useful? QUESTION 1: It is argued that translation research is needed in order to increase the odds that interventions found to be efficacious can be effectively translated into practices that will produce desired outcomes. Thus, evidence from translation research is a very important component of the science base needed to guide innovation in practice. Another reason of concern in preparing translation researchers is the growing pace of research into the efficacy of interventions, which accelerates the need for translation research. Furthermore, the emergence of clinical doctoral programs in nursing that will be seeking faculty with expertise in translation research supports the need for preparing scientists in translation research. QUESTION 2: To determine whether translation research was visible in current research-intensive doctoral programs, a Web-based review of these programs offered by colleges and universities in the database of the American Association of Colleges of Nursing (AACN) was conducted in the fall of 2003. The search revealed that in the 79 programs surveyed, no school identified an area of emphasis in terms that suggested a component of translation science such as research dissemination or utilization, knowledge transfer, diffusion of innovation, or technology transfer. Less than a dozen courses could be located that focused on topics related to translation research or translation science. QUESTIONS 3 AND 4: The case is made that more attention should be given to preparing translation scientists in research-intensive doctoral programs in nursing, and several strategies were suggested for moving toward that goal.

Curriculum↗
PubMed2002

Decreasing reliance on mineral nitrogen--yet more food.

Higher crop production normally demands higher nutrient application rates and consequently increased mineral nitrogen use. With food demand for 2030 estimated around 2800 mill. tonnes (t) yr-1, the corresponding mineral N consumption figure is 96 mill. t (78 mill. t yr-1 in 1995/1997). Global-level mineral N losses to the environment from mineral fertilizer use are currently 36 mill. t yr-1, worth USD 11,700 mill. and with adverse environmental impacts. However, innovative fertilizer-use efficiency (FUE) technologies enable increased production with a less than a proportionate increase in mineral-N use. Moreover, nitrogen-nutrient supplies can be augmented through improvements in agricultural production systems and in the exploitation of alternative sources such as biological nitrogen fixation (BNF). By 2030, with adequate policy, technology transfer, research and investment support, the on-farm adoption of BNF and FUE technologies could generate savings of 10 mill. t yr-1 of mineral N, worth USD 3300 mill.

Agriculture↗
PubMed2002

Future AAC technology needs: consumer perspectives.

This article suggests the need for rethinking the role that consumer perspectives will play (and ought to play) in the design and development of future augmentative and alternative communication (AAC) technologies. After carefully defining what they mean by "AAC consumers," "consumer perspectives," and "AAC technologies," the authors consider the extent to which current research has illuminated our understanding of (1) how consumers view AAC technologies and (2) how consumers themselves would define future technology needs. It's not a pretty picture. While it is clear that there already exist specific constructs and methods that could enable researchers and developers to learn more about consumer perspectives, it is equally clear that few, if any, researchers make much use of these constructs and methods. The authors focus specifically on ways that consumer perspective can helpfully infuse participatory action research, technology transfer processes, and ergonomics. In addition, the authors consider how research that investigates the ways in which assistive technologies impact the daily lives of individuals with severe communication impairment also influences public policy issues, which can in turn affect future definitions of AAC technology needs. Throughout the article, the authors advocate for a paradigm shift in the quantity and quality of the collaborations that occur between AAC consumers and AAC researchers, manufacturers, and developers. Augmented communicators and their families have a major stake in all types of research that can affect the design and development of AAC devices and accessories, and the results of this research, in turn, can affect public policy decisions about AAC technologies. This makes it all the more important that AAC consumers be involved at each step of the research and development process.

Communication Devices for People with Disabilities↗
PubMed1994

Market requirements for advanced biosensors in healthcare.

The Advanced Sensors Technology Transfer Programme (ASTTP) of the Department of Trade and Industry, stimulates and encourages the commercial exploitation of new sensor technology by UK industry. This review is based on the findings of a Study, sponsored under this programme, into the Market Requirements and Opportunities for Advanced Sensors in the Healthcare Industry.

Biosensing Techniques↗
PubMed2007

[The National Genome Research Network. Genome research in Germany].

In 2001 Germany's Federal Ministry of Education and Research (BMFM) initiated the National Genome Research Network (NGFN). The goals of the NGFN are the investigation of the molecular basis of common diseases to improve new methods for prevention, diagnosis and therapy. The disease-oriented genome networks investigate cardiovascular diseases, cancer, diseases of the nervous system, diseases due to environmental factors and infection, and inflammation. They are supported by technological platforms and a component for technology transfer. The explicit aims include better integration of public health research and economy in order to gain an efficient economical and technological utilisation and application in community health. This article describes the creation of the NGFN in the context of international and national genome research, shows the structure and content of the NGFN and gives examples for NGFN research in networks on a highly, internationally recognised level.

Academies and Institutes↗