Detection and interaural time discrimination of a sinusoid masked by interaurally delayed white noise.
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Just-noticeable differences (jnds) of both interaural time delay (ITD) and interaural intensity difference (IID) were measured for binaural tones in the presence of broadband maskers. The tones were presented at 50 dB SPL, the target frequency was 500 Hz, and the masker frequency was 100-1000 Hz, with various combinations of ITD and IID. The time and amplitude jnds exhibit similar dependencies on target-to-masker ratio and masker type. At a given target-to-masker ratio, discrimination was generally best in the presence of diotic maskers and worst in the presence of the interaurally out-of-phase maskers. Results for the other masker types examined tended to fall in between these two extremes. Many of these data trends are consistent with predictions of the lateralization model and the position-variable model based on auditory-nerve activity.
A two-interval, two-alternative forced choice task was used to estimate frequency difference limens (DLs) for individual harmonics within complex tones, and DLs for the periodicity (i.e., number of periods per s) of the whole complexes. For complex tones with equal-amplitude harmonics, the DLs for the lowest harmonics were small (less than one percent). The DLs increased rather abruptly around the fifth to seventh harmonic. The highest harmonic in each complex was also well discriminated, and the discriminability of a single high harmonic was markedly improved by increasing its level relative to the other components. The DL for a complex tone was generally smaller than the frequency DL of its most discriminable component. The DL for a complex was found to be predictable from the DLs of the harmonics comprising the complex, using a formula derived by Goldstein [J. Acoust. Soc. Am. 54, 1496-1516 (1973)] from his optimum processor theory for the formation of the pitch of complex tones. The DL for a complex is sometimes primarily determined by high harmonics, such as the highest harmonic, or a harmonic whose level exceeds that of adjacent harmonics. We also measured intensity DLs for individual harmonics within complex tones. The intensity DLs were smallest for low harmonic numbers, and for the highest harmonic in a complex. An excitation-pattern model was used to determine whether the frequency DLs of harmonics within complex tones could be explained in terms of place mechanisms, i.e., in terms of changes in the amount of excitation at appropriate frequency places. We conclude that place mechanisms are not adequate, and that information about the frequencies of individual harmonics is probably carried in the time patterning of neural impulses.
An experiment was carried out, investigating the relationship between the just noticeable difference of fundamental frequency (jndfo) of three stationary synthesized vowel sounds in noise and the signal-to-noise ratio. To this end the S/N ratios were measured at which listeners could just discriminate a series of changes in fo in the range from 10% to 0.5%. Similar measurements were obtained for pulse trains and for pure tones as a reference for the results. A measure of S/N ratio based on an approximation of the critical bandwidth appeared to provide a fairly good predictor of the masked threshold of each signal, measured in a second experiment. Using this measure, it was found that a given change in the fundamental of a pulse train could be discriminated at a lower S/N ratio than in a pure tone with a frequency equal to that fundamental. The results for the vowel sounds were found to be in between those for a low-frequency pure tone and those for a pulse train. Owing to the signal-generation method (viz., changing fo by changing the sampling frequency), three cues could in principle be used to discriminate a change in the fundamental of a vowel: A change in the residue pitch, a change in the pitch of a single prominent harmonic, or a change in the spectral envelope of the signal. It can be inferred from the results that the subjects used that particular cue which yielded best performance. Which cue was optimal depended not only on the vowel but also on fo and on the presented change in fo.(ABSTRACT TRUNCATED AT 250 WORDS)
Band-narrowing estimates of the critical bandwidth (CB) are consistently larger than critical-ratio (CR) estimates for the same signal frequency. Bilger [in Hearing and Davis: Essays Honoring Hallowell Davis, edited by S.K. Hirsh et al. (Washington U.P., St. Louis, 1976), p. 191] proposed that this difference could be accounted for by reference to intensity-discrimination performance [CR(Hz)/CB(Hz) = delta I/I]. To test this hypothesis, band-narrowing, critical-ratio, and intensity-discrimination data were collected for four normally hearing, well-trained listeners. Signal frequency was 2000 Hz and two noise levels were used: 20 and 50 dB N0. The relations proposed by Bilger among critical-bandwidth estimates from band-narrowing experiments, critical-ratio estimates from pure-tone detection in wideband noise, and intensity discrimination for a critical-band-wide noise in wideband noise are not supported by the results of individual listeners, or results averaged across listeners.
Thresholds for discrimination between pure and tempered musical intervals consisting of simultaneous complex tones (fundamental frequencies f1 and f2) were investigated. For these tones the main clue for the discrimination of pure intervals (f1:f2 = p:q; p and q small integers) from moderately tempered intervals (f1:f2 approximately p:q) is absence versus presence of beats. The strength of the beats (level difference between envelope maximum and minimum or level-variation depth D) was manipulated by introduction of differences in level (delta L) between the two tones. In each of three experiments the discrimination thresholds (DTs) were determined for 13 intervals with different values for p and/or q. Experiment 1 showed that there is a simple relation between frequency-ratio complexity and discriminability: DTs gradually increased (smaller values of delta L) with increasing p + q. Experiment 2, in which tones with harmonics of equal amplitude were used, indicated that level of the interfering harmonics was not responsible for the relation between DT and p + q. Yet, Experiment 3, in which the spectral content of the tones was varied, clearly showed that for all intervals DT had been determined by the interference between nearly coinciding harmonics. Detailed analysis of the results revealed that the relation between DT and ratio complexity might have been the result of masking.
Intensity discrimination thresholds were measured for gated 100-ms, 1000-Hz tones. Discrimination thresholds were measured at several intensities near absolute threshold as well as at 30, 60, and 90 dB SPL. Psychometric functions were obtained for several of these discrimination conditions, and for detection of the signal in quiet. The results showed that Weber's law is approximately valid for standards as low as 0 dB SL. Small amounts of negative masking were observed even when the data were expressed in terms of increment energy. The psychometric functions for the discrimination conditions had a similar form and were shallower than the psychometric function for the detection of a signal in quiet. A similar set of conditions was run in the presence of a continuous, broadband noise. The results were generally in agreement with those obtained in quiet, but slight differences suggested that the variability which limits performance in the two conditions is different. The results are discussed in terms of the effects of nonlinear transduction, the effects of uncertainty, and contrast mechanisms as proposed by Laming [Sensory Analysis (Academic, London, 1986)].
Physiological responses of the auditory leg nerve were recorded in the tettigoniid Metaballus litus to suprathreshold tone pulses of 12.45 kHz, which is close to the carrier frequency of the male's call. This stimulus tone frequency was determined by characterizing the polar response of the foreleg. Physiological threshold of the receptors was calculated from intensity input/output curves, and the experimental stimulus was set at 40 dB above this threshold value. There was low variance in threshold values between preparations. Continuous octave filtered white noise centered on the stimulus frequency was presented at the same time as the tone pulse at increasing intensities. The summed action potentials (SAPs) of the whole leg nerve were averaged over 256 stimulus presentations and the magnitude of the response was calibrated to dB values. The range of noise levels was set between that inducing no decrease in the SAP response to the tone pulse stimulus, up to a masking intensity where the response to the tone pulse was only just observable. Decrement in SAP magnitude was linear, and complete masking occurred when the noise level was 20-25 dB above the initial level of zero masking. This final level was comparable in magnitude to the sound-pressure level of the tone pulse and within the natural range of the insect's auditory behavior. Following the cessation of the noise signal, the SAPs were monitored over intervals of 2 min until the SAP asymptoted to the preexperimental condition. The reduction in SAP magnitude during noise presentation was attributed to a loss in synchrony from the individual tympanic receptors.
Discrimination of interaural differences of level (IDLs) was measured for pure tones as a function of frequency and as a function of the interaural difference of phase or level of a standard. Varying the interaural difference of the standard was assumed to change the lateral position of its intracranial image. Threshold IDLs were approximately constant over a frequency range from 200-5000 Hz, except in a region near 1000 Hz where they were slightly elevated. Thresholds increased as the value of the standard interaural differences of phase or level increased, implying that interaural resolution declines as the lateral image moves away from midline. The results are generally consistent with the predictions of current models of lateralization, but additions to these models are required in order for them to account for the slight frequency dependence of threshold IDLs.
Research on the perception of vowels in the last several years has given rise to new conceptions of vowels as articulatory, acoustic, and perceptual events. Starting from a "simple" target model in which vowels were characterized articulatorily as static vocal tract shapes and acoustically as points in a first and second formant (F1/F2) vowel space, this paper briefly traces the evolution of vowel theory in the 1970s and 1980s in two directions. (1) Elaborated target models represent vowels as target zones in perceptual spaces whose dimensions are specified as formant ratios. These models have been developed primarily to account for perceivers' solution of the "speaker normalization" problem. (2) Dynamic specification models emphasize the importance of formant trajectory patterns in specifying vowel identity. These models deal primarily with the problem of "target undershoot" associated with the coarticulation of vowels with consonants in natural speech and with the issue of "vowel-inherent spectral change" or diphthongization of English vowels. Perceptual studies are summarized that motivate these theoretical developments.
There has been experimental evidence pointing to at least two pitch mechanisms, the first involving low-order harmonics that are resolved along the basilar membrane, and the second a periodicity mechanism that depends only on the repetition rate of the time waveform on the basilar membrane. If this time waveform is derived from repeated bursts of sinusoidal tone, the second mechanism might be the sole pitch mechanism. It is found that this can be so up to rates as high as 250 bursts of 4978-Hz tone per second. The stimuli used are periodic patterns of equally spaced tone bursts, with either successive tone bursts in the same phase, or every fourth tone burst 180 degrees out of phase with respect to the rest. Up to a critical transitional rate of tone bursts a second, the two sequences sound exactly the same, despite their different fundamental frequencies and frequency separation of harmonics. Critical rate data are given for sinusoidal bursts of seven different frequencies. Critical rates appear to be closely related to the critical bandwidth. Pitch matching appears to be consistent with these observations; it is on rate below the critical rate and can be on fundamental frequency above the critical rate.
The Weber fraction was measured for a 25-ms sinusoidal pedestal presented 100 ms before, or 100 ms after, an intense narrow-band noise. Consistent with the finding of Zeng et al. [Hear. Res. 55, 223-230 (1991)], the forward masker caused an elevation in the Weber fraction at medium pedestal levels. Surprisingly, however, a much larger midlevel elevation was observed in the backward masking conditions; in some cases, the Weber fraction was increased by over 20 dB by the backward masker. In both masking conditions, presenting a notched noise simultaneously with the pedestal reduced the magnitude of the midlevel elevation. These results indicate that it is possible to produce large masking effects on intensity discrimination in conditions where there is no possibility of the masker affecting the representation of the pedestal at the level of the auditory nerve. This suggests that there may be "central" processes underlying the original finding of Zeng et al. Despite the similarities in the results, however, it is not certain that the elevations seen in the forward and backward masking conditions were caused by the same mechanisms.
A maximum-likelihood method was applied in measurements of frequency and intensity discrimination for aged and young normal-hearing subjects with closely matched audiograms. This method was preferred over other psychophysical procedures because it is efficient and controls experimental variance, features that are highly desirable for testing aged subjects. In order to implement the method, psychometric functions for each task were also measured from young subjects using a constant-stimuli procedure. For the young subjects, the differential thresholds obtained from these two procedures were generally comparable. Further, both sets of data were consistent with previous literature, indicating that the maximum-likelihood method was successfully applied for frequency and intensity discrimination. A frequency-dependent difference between young and aged subjects in both frequency and intensity discrimination was observed. Even with closely matched audiograms, aged subjects demonstrated poorer discrimination abilities than young subjects. The age-related difference was always largest at 500 Hz and decreased as frequency increased.
Difference thresholds for seated subjects exposed to whole-body vertical sinusoidal vibration have been determined at two vibration magnitudes [0.1 and 0.5 ms(-2) root mean square (r.m.s.)] and at two frequencies (5 and 20 Hz). For 12 subjects, difference thresholds were determined using the up-and-down transformed response method based on two-interval forced-choice tracking. At both frequencies, the difference thresholds increased by a factor of five when the magnitude of the vibration increased from 0.1 to 0.5 ms(-2) r.m.s. The median relative difference thresholds, Weber fractions (deltaI/I), expressed as percentages, were about 10% and did not differ significantly between the two vibration magnitudes or the two frequencies. It is concluded that for the conditions investigated the difference thresholds for whole-body vibration are approximately consistent with Weber's Law. A vibration magnitude will need to be reduced by more than about 10% for the change to be detectable by human subjects; vibration measurements will be required to detect reductions of less than 10%.
Microelectrode studies in nonhuman primates and other mammals have demonstrated that many neurons in auditory cortex are excited by pure tone stimulation only when the tone's frequency lies within a narrow range of the audible spectrum. However, the effects of auditory cortex lesions in animals and humans have been interpreted as evidence against the notion that neuronal frequency selectivity is functionally relevant to frequency discrimination. Here we report psychophysical and anatomical evidence in favor of the hypothesis that fine-grained frequency resolution at the perceptual level relies on neuronal frequency selectivity in auditory cortex. An adaptive procedure was used to measure difference thresholds for pure tone frequency discrimination in five humans with focal brain lesions and eight normal controls. Only the patient with bilateral lesions of primary auditory cortex and surrounding areas showed markedly elevated frequency difference thresholds: Weber fractions for frequency direction discrimination ("higher"-"lower" pitch judgments) were about eightfold higher than Weber fractions measured in patients with unilateral lesions of auditory cortex, auditory midbrain, or dorsolateral frontal cortex; Weber fractions for frequency change discrimination ("same"-"different" pitch judgments) were about seven times higher. In contrast, pure-tone detection thresholds, difference thresholds for pure tone duration discrimination centered at 500 ms, difference thresholds for vibrotactile intensity discrimination, and judgments of visual line orientation were within normal limits or only mildly impaired following bilateral auditory cortex lesions. In light of current knowledge about the physiology and anatomy of primate auditory cortex and a review of previous lesion studies, we interpret the present results as evidence that fine-grained frequency processing at the perceptual level relies on the integrity of finely tuned neurons in auditory cortex.
Many animals use duration to help them identify the source and meaning of a sound. Duration-sensitive neurons have been found in the auditory midbrain of mammals and amphibians, where their selectivity seems to correspond to the lengths of species-specific vocalizations. In this study, single neurons in the rat inferior colliculus (IC) were tested for sensitivity to sound duration. About one-half (54%) of the units sampled showed some form of duration selectivity. The majority of these (76%) were long-pass neurons that responded to sounds exceeding some duration threshold (range: 5-60 ms). Band-pass neurons, which only responded to a restricted range of durations, made up 13% of duration-sensitive neurons (best durations: 15-120 ms). Other units displayed short-pass (2%) or mixed (9%) response patterns. The majority of duration-sensitive neurons were localized outside the central nucleus of the IC, especially in the dorsal cortex, where more than one-half of the neurons sampled had long-pass selectivity for duration. Band-pass duration tuned neurons were only found outside the central nucleus. Characteristics of duration-sensitive neurons in the rat support the idea that this filtering arises through an interaction of excitatory and inhibitory inputs that converge in the IC. Band-pass neurons typically responded at sound offset, suggesting that their tuning is created through the same mechanisms that have been described in echolocating bats. The finding that the first-spike latencies of all long-pass neurons were longer than the shortest duration to which they responded supports the idea that they receive transient inhibition before, or simultaneously with, a sustained excitatory input. The ranges of selectivity in rat IC neurons are within the range of durations of rat vocalizations. These data suggest that a population of neurons in the rat IC have evolved to transmit information about behaviorally relevant sound durations using mechanisms that are common to all mammals, with an emphasis on long-pass tuning characteristics.
The dynamics at the brain level (quantitative EEG), plasma kinetics and effects on blood pressure and heart rate of the Ca antagonists, darodipine (slow-release, 50- 200 mg) and nimodipine (30 mg), were compared in a double-blind cross-over study on healthy volunteers during a 9-hour period following single drug/placebo administration. Increased EEG total power was observed after 100 and 200 mg daropidine; a concomitant decrease of 14.5-32.0 Hz relative power was observed at 100 mg. The 50-mg dose proved ineffective. These effects were correlated with the darodipine plasma concentration only at the 100-mg dose, with indications of an active concentration interval at approximately 5-10 ng/ml; a reduction in diastolic blood pressure and increased heart rate proved to be linearly correlated with the drug plasma concentration throughout the entire concentration range. Comparable EEG effects were observed after nimodipine, but they did not correlate with the plasma concentration. Implications of the predictability of the brain effect from the drug plasma concentration and differential thresholds for the brain action and effects on (peripheral) circulation are suggested.
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