Search PubMed⌕ Search
Home/Archive/PubMed

PubMed · 970533

Neonatal diaphragmatic dysfunction.

H A Wexler·C A Poole
View original source ↗Export metadata ↓

Abstract

Several unusual diaphragmatic problems in the neonate are presented and a new potential complication of the negative pressure respirator is illustrated. The association of bilateral diaphragmatic eventrations with chromosome anomalies is emphasized. In our experience the appearance of the chest on frontal and lateral views is usually so characteristic that no further evaluation is required. The relationship between several neuromuscular disorders and diaphragmatic dysfunction is discussed. A case of congenital myotonic dystrophy with unilateral eventration is illustrated.

Explore related subjects

Chromosomes, Human, 13-15Chromosomes, Human, 16-18DiaphragmDiaphragmatic EventrationFemaleHumansIatrogenic DiseaseInfant, NewbornInfant, Newborn, DiseasesMaleMuscular DiseasesMyotonic DystrophyRadiographyRespiratory TherapyTrisomyCase ReportsJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

H A Wexler, C A Poole. 1976. Neonatal diaphragmatic dysfunction.. https://doi.org/10.2214/ajr.127.4.617

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed1995

Trisomy among fetuses with noncoiled umbilical blood vessels.

OBJECTIVE: To examine the relationship between trisomy and neonates with noncoiled umbilical blood vessels. STUDY DESIGN: The incidence of and risk factors for trisomy were evaluated among 48 consecutive, live-born neonates with noncoiled umbilical vessels. RESULTS: Four cases (8.3%) of trisomy were identified. One case of mosaicism was also noted (2.1%). In no case was noncoiling of the umbilical vessels the only identifiable risk factor. The remaining 43 infants (89.6%) were phenotypically normal, although not all underwent karyotype analysis. CONCLUSION: Noncoiled umbilical blood vessels alone do not appear to represent an independent risk factor for trisomy. Rather, identification of noncoiled blood vessels should prompt a thorough search for other abnormalities.

Chromosomes, Human, 13-15↗
PubMed1990

Acrocentric interconnections and NOR variants in human lymphocytes.

Acrocentric interconnections and NOR (nucleolus organizer region) variants are frequently observed in silver-stained metaphase preparations from lymphocytes of phenotypically normal individuals. The types of interconnections and of NOR variants are outlined. It is speculated that the satellite acrocentrics (both normal and variant) are the consequence of breakage and recoiling of these interconnections. Awareness of these two features of the human genome may facilitate understanding of the NOR/nucleolus interaction(s) in such important processes as nucleolus formation and in development and/or diagnosis of disease states (i.e., malignancy).

Chromosomes, Human, 13-15↗