PubMed · 9607753
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I Segev. 1998-05-21. Sound grounds for computing dendrites.. https://doi.org/10.1038/30340
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The development of modern hearing aids has been so great that they now represent the cutting edge of micro-electronics. Flexibility has been enhanced by computer-aided programming of the devices, and particularly by digital signal processing, developments which enable improved customization. Increased knowledge of the pathophysiology of the auditory system, fundamental processes in central auditory pathways, and cognitive function enable technological developments to be exploited, thus enhancing our ability to cope with an increasingly broad spectrum of hearing impairment, ranging from mild high-frequency loss to severe loss across the entire frequency range.
An approach to understanding biological processes underlying speech perception, is to discover how speech sounds are represented in the central auditory system and to relate that representation to the perception of speech as a meaningful acoustic signal. Research from our group that pertains to the neurophysiologic representation of speech in the central pathways is reviewed here. Specifically considered is the relation between the representation of sound in the auditory pathway and the perception/misperception of speech, and neurophysiologic plasticity associated with speech-sound perceptual learning.
Recent rapid progress in identifying genes involved in deafness has suggested that a wide range of different types of gene products can result in hearing impairment, which, given the complexity of the auditory system, is not surprising. However, what has given some surprises are the unexpected expression patterns within the ear of some of these genes, which suggests that cochlear physiologists need to look again at some of the cell types involved.