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PubMed · 9532529

Fluid-bed microencapsulation of ascorbic acid.

Z Knezevic·D Gosak·M Hraste·I Jalsenjak
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Abstract

Ascorbic acid has been fluidized and microencapsulated with three different hydrophobic coating materials by the top-spray method. The experiments were conducted with polymethacrylate coating material formulated as a water dispersion, and ethyl-cellulose and waxy coating material both formulated as organic solutions. Characteristics of the fluidized bed procedure in conical geometry have been determined by estimation of two parameters: bed porosity and total pressure drop. A satisfactory agreement between experimental and calculated values has been reached. The following properties of the microencapsulated ascorbic acid have been determined: core content, bulk and tapped density, crystal size distribution prior and after microencapsulation, surface morphology and release profile. The comparison and evaluation of different hydrophobic coating materials have been performed on the basis of these findings.

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Ascorbic AcidCapsulesDrug CompoundingMethylcellulosePolymethacrylic AcidsPorosityStearatesTemperatureJournal Article

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Z Knezevic, D Gosak, M Hraste, I Jalsenjak. Fluid-bed microencapsulation of ascorbic acid.. https://doi.org/10.3109/02652049809006853

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Effect of light on ascorbic acid biosynthesis and bioinformatics analysis of related genes in Chinese chives.

Ascorbic acid (AsA) is an essential nutritional component and powerful antioxidant in vegetables, and in plants, AsA levels are regulated by light. AsA levels in the leaves of Chinese chive (Allium tuberosum Rottler ex Spr), a popular vegetable, are poorly understood. Thus, this study was performed to assess the influence of light on AsA biosynthesis in chive and select related genes (AtuGGP1 and AtuGME1); in addition, bioinformatic analyses and gene expression level assays were performed. The biological information obtained for AtuGGP1 and AtuGME1 was analysed with several tools, including NCBI, DNAMAN, and MEGA11. After different light treatments were performed, the Chive AsA content and AtuGGP1 and AtuGME1 expression levels were determined. These results suggest that 1) compared with natural light, continuous darkness inhibited AsA synthesis in chives. 2) The amino acid sequences of AtuGGP1 and AtuGME1 are very similar to those of other plants. 3) The trends observed for the expression levels of AtuGGP1 and AtuGME1 were consistent with the AsA content observed in chives. Hence, we speculated that light controls AsA biosynthesis in chives by regulating AtuGGP1 and AtuGME1 expression. This study provided impactful and informative evidence regarding the functions of GGP and GME in chives.

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