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PubMed · 9216296

Testing a test.

J Koziol-McLain·S R Lowenstein
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Data Interpretation, StatisticalDiagnostic Tests, RoutineHumansSensitivity and SpecificityJournal Article

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J Koziol-McLain, S R Lowenstein. 1997. Testing a test.. https://doi.org/10.1016/s0099-1767(97)90115-x

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PubMed1999

[Mathematical coupling and "regression to the mean". A statistical case history].

"Regression to the mean" (RTM) is a statistical phenomenon originating from the random variation of variables rather than a true association between the variables. RTM is closely linked to mathematical coupling; unawareness of these phenomena may lead to misinterpretation of data. A study examining intracranial pressure before and after infusion of manitol is presented, in which mathematical coupling caused a highly significant (but spurious) correlation between the analysed data. The significance of RTM and mathematical coupling is demonstrated by analysis of a data set derived from random numbers.

Data Interpretation, Statistical↗