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PubMed · 8962063

Conserved circadian elements in phylogenetically diverse algae.

M Mittag
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Abstract

Circadian expression of the luciferin-binding protein (LBP) from the dinoflagellate Gonyaulax polyedra is regulated at the translational level. A small interval in the lbp 3'-untranslated region, which contains seven UG-repeats, serves as a cis-acting element to which a trans-acting factor (CCTR) binds in a circadian manner. Its binding activity correlates negatively with the circadian expression of LBP. Here I report the identification of a protein in the green alga Chlamydomonas reinhardtii that represents a CCTR analog. It binds both specifically and under control of the circadian clock to the UG-repeat region. The data show for the first time that circadian cis-elements implicated in translational regulation have been conserved during evolution.

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AnimalsChlamydomonas reinhardtiiCircadian RhythmPhylogenyRNA-Binding ProteinsRepetitive Sequences, Nucleic AcidJournal ArticleResearch Support, Non-U.S. Gov't

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M Mittag. 1996-12-10. Conserved circadian elements in phylogenetically diverse algae.. https://doi.org/10.1073/pnas.93.25.14401

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