DNA immunization.

D E Hassett; J L Whitton

doi:10.1016/0966-842x(96)10048-2

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PubMed · 8856868

DNA immunization.

D E Hassett·J L Whitton

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Abstract

Inoculation with plasmid DNA vectors encoding immunogenic proteins induces both humoral and cell-mediated immune responses, which often provide protective immunity. Although many questions regarding the mechanism, efficacy and safety of DNA immunization remain to be addressed, this approach may offer a safer and more cost-effective alternative to conventional vaccines.

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Animals Communicable Disease Control Communicable Diseases Drug Administration Routes Drug Design Genetic Vectors Immunization Mice Vaccines, DNA Journal Article Research Support, U.S. Gov't, P.H.S.Review

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D E Hassett, J L Whitton. 1996. DNA immunization.. https://doi.org/10.1016/0966-842x(96)10048-2

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