PubMed · 85231
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1979-03-17. John H. Knowles.. https://pubmed.ncbi.nlm.nih.gov/85231/
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[Our original introduction to "Listen to the Patient" is published again to emphasize the Journal's commitment to this important series.] For more than 50 years, Cancer has been devoted to exploring every facet of malignant neoplasia, from morphology to therapy, from epidemiology to biology, from historical perspective to basic science. One aspect, however, needs emphasis, namely, the human being who bears the burden of the cancer. For this reason and with the encouragement of the Editor, we have undertaken to remedy this situation by directing attention to the fears and frustrations, hopes and expectations, and feelings and thoughts of all kinds of the person who has cancer, who is worried about it, and who is dependent on physicians specialized in its diagnosis and management. For doctors to be understanding of the very deep needs of patients with cancer, it is requisite that they be privy to authentic, but often unspoken, expressions of a patient's anxieties about physical and emotional pain, loss of control over personal destiny, and plain dread of dying and of the end of cherished relationships. The essay that follows was written by a woman diagnosed with cancer who felt herself alone and in need of talking with others who faced the same diagnosis. Barrie R. Cassileth, Ph.D. Integrative Medicine Service, Memorial Sloan-Kettering Cancer Center, New York, New York A. Bernard Ackerman, M.D. Ackerman Academy of Dermatopathology, New York, New York.
The Council for Medical and Health Research (MW-NWO) assessed the scientific quality of research proposals submitted to the Dutch Investigative Medicine Fund, and analysed if there had been changes over time in the proportion of proposals which the MW-NWO advised to reject, the role of reports of external reviewers and the most important methodological flaws. In the period 1995-1999 'reject' had been advised for an average of 50% of the proposals, with a tendency to a smaller proportion in recent years. In nearly half of the proposals the judgements of external reviewers were not in agreement with each other. There was only a weak correlation between the judgements of the reviewers and the final advice of NWO. Among the most important flaws mentioned in the NWO advice were: efficacy not proven (a prerequisite for the Fund), proposed study not needed to solve the policy problem and methodological flaws, e.g. design and power calculation not adequate, deficiencies of inclusion and exclusion criteria.
The Cancer Research Foundation of America has played a key role in "fueling the engine" of cancer prevention progress through a national research grant and education program. It is one of the nation's leading cancer prevention organizations, and has helped move prevention science from the fringes to the mainstream. Since its inception in 1985, it has provided more than $42.1 million in funding for cancer prevention research and education. It has supported pioneering research and translated it into practical information to educate men, women, and children about how to reduce their cancer risk. As more and more research results in practical interventions to prevent cancer, the Foundation will continue to act in an anticipatory way to help smooth the way for rapid translation of information from scientific study to consumer information through education and awareness initiatives. As we celebrate our 15th anniversary, the Cancer Research Foundation of America has recommitted itself to its role as a catalyst for change. It hopes to help the nation move toward a future in which harsh and often toxic treatment for cancer is replaced with a sane policy of cost-effective early intervention-healthy lifestyle education, detection of premalignant conditions, and therapies that spare healthy tissue. The Foundation believes there is a groundswell of support for making cancer prevention and early detection a national priority.