PubMed · 7634006
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R H Geelkerken, J H van Bockel. 1995. Mesenteric revascularisation.. https://doi.org/10.1016/s1078-5884(05)80031-0
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Hepatitis C virus is now known to be the causative agent for at least 90% of non-A, non-B hepatitis cases. In the few years since its characterization, much has been learned about this virus and the scope of its disease. It now appears that close to 100% of infections may become chronic, with delayed but potentially devastating consequences. The treatment options for hepatitis C remain limited and less than satisfactory. A vaccine seems to be a distant goal, but other strategies for treatment may be closer. For now, the best option remains prevention.
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Thirty-eight partial middle turbinate resections from 20 patients undergoing endoscopic sinus surgery were evaluated by histopathology of mucosa and bone and by computed tomography (CT) appearance prior to resection. Histopathologic analysis revealed not only mucosal inflammation but also chronic osteitis of the bone in all patients with sinus disease. The preoperative CT was accurate in predicting turbinate osteitis when the scans displayed advanced grades III and IV disease. These findings suggest that in advanced disease, conservative partial middle turbinate resections may be necessary to remove chronically infected bone from the osteomeatal complex. Because it is unsafe to remove all of the middle turbinate, consideration should also be given to long-term antibiotic therapy to treat the osteitis found in advanced disease.