PubMed · 7625185
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A J Gelenberg, J O Ottosson. 1995. Editorial statement.. https://doi.org/10.1111/j.1600-0447.1995.tb09756.x
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Indications, efficacy and side-effects of the selective serotonin reuptake inhibitors (SSRI) have now been investigated in numerous studies of varying quality. In the case of some disorders, SSRI have been shown to produce a very positive response-for example compulsive disorders and seasonal winter depression, so-called. In view of their effectiveness, SSRI are now considered first-line drugs for these indications. With respect to other disorders, SSRI are recommended because of their favorable side-effect profile. In further indications the efficacy reported in individual studies need further corroboration. Differences between individual SSRI, which mainly concern kinetics, are described.