PubMed · 7070739
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D P Mikhailidis, R A Hutton, P Dandona. 1982. Postmenopausal observations.. https://pubmed.ncbi.nlm.nih.gov/7070739/
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Medicine has till now payed less attention to psychosocial aspects of the menopause than to the hormonal changes of woman in this period of life. The climacteric woman is characterized in the language of the organ-medicine by faulty terms. The lack of hormones is considered to be a disease which has to be treated. The tendency to medicalize the menopause is in contradiction to the results of recent prospective studies. These studies show that pre- and postmenopausal complaints are less severe than they are often described. Psychosocial risk factors before and during the climacteric phase favour the development of psychic and psychosomatic symptoms. The climacteric period of life has to be seen as a vulnerable time of life which should be considered in the treatment of menopausal women.
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OBJECTIVE: The aim of the study was to investigate clinically and urodynamically the effects of hormonal replacement in the treatment of genuine stress urinary incontinence in postmenopausal females. METHODS: Clinical and urodynamic variables of 30 postmenopausal women with genuine stress urinary incontinence were evaluated after 3 months' treatment with conjugated estrogens plus progestogens. Urodynamic evaluations were performed in all patients before and after treatment. RESULTS: Forty-six percent of the patients treated medically were judged to be cured and 43% were judged to be markedly improved. Maximum urethral closure pressure, maximum cystometric capacity and mean flow were significantly increased. Residual urine and diurnal and nocturnal voluntary micturition were markedly decreased (P < 0.05). CONCLUSION: We conclude that hormone replacement in the form of conjugated estrogens plus progestogens results in the clinical and urodynamic improvement of genuine stress urinary incontinence in postmenopausal women.