PubMed · 6364866
The source did not provide an abstract. Follow the original record for more information.
Explore connections, maps & timelines
J J Texier. 1983. [Computer information processing and cerebral hemodynamics].. https://pubmed.ncbi.nlm.nih.gov/6364866/
Cite the original work for its findings. Save a collection to share your selection of sources.
KEEP EXPLORING
Explore the source record for details and available documents.
Dual gated transcranial Doppler (TCD) systems have the potential to distinguish definitively embolic events in the cerebral circulation from artefact. While developing such a system, three curious observations were made and are the subject of this article. The first was that the velocity of propagation of an embolus in an artery as calculated from the ultrasonic Doppler shift was, in many cases, dramatically different from the velocity calculated using a time of flight method. The second observation was that the durations of embolic signals measured in two gates were often very different, despite the received gates being identical in length. The third observation was that some emboli detected in the deeper gate did not appear in the more superficial gate, and, more surprisingly (as has recently been reported by another group), some emboli that had not previously appeared in the deeper gate appeared in the more superficial gate. It is hypothesised that all of these effects can be explained in terms of the geometry of the middle cerebral artery in relation to the interrogating ultrasound beam. None of these effects should detract from the usefulness of TCD, but will need to be widely appreciated if dual gated measurements of cerebral emboli are to be interpreted correctly.
Near infrared spectroscopy (NIRS) was used to investigate the effect of behavioural states on changes of oxygenated (O2Hb), deoxygenated haemoglobin (HHb) and total haemoglobin (tHb), during endotracheal suctioning. In an open prospective design, NIRS measurements have been done during 20 suctioning episodes in 13 preterm neonates. Heart rate, arterial oxygen saturation, and carbon dioxide tension were monitored continuously. Behavioural state (BS) observations were made and documented as well. The statistical analysis showed that in patients who were active, with crying periods during suctioning (behavioural states 4-5), changes of oxygenated (p < 0.005) and deoxygenated haemoglobin (p < 0.05), as well as of arterial oxygen saturation (p < 0.05) and heart rate (p < 0.05) were significantly greater than in patients who were quiet with predominant behavioural state 1, 2 and 3. These results underline the influence of behavioural states on the physiological answers to endotracheal suctioning. NIRS proved to be a valuable tool to evaluate possible harmful effects of different suctioning techniques.