Complement C3 receptors: structure and function.

M A Arnaout; H R Colten

doi:10.1016/0161-5890(84)90009-9

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Complement C3 receptors: structure and function.

M A Arnaout·H R Colten

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Abstract

Significant progress has been made during the past few years toward elucidating the structure and function of various C3 receptors. Better understanding of the biochemical basis of the immune adherence phenomenon has been achieved. The availability of polyclonal and monoclonal antibodies to C3 receptors allowed more accurate studies of the cellular distribution of these receptors. Finally, advances in our knowledge of the functional properties of the C3 receptors and their relationship to specific cell surface molecules was facilitated by recognition of a patient deficient in various receptor-mediated functions. All together these developments will soon make it possible to describe in detail the molecular events involved in the modulation of complement receptor coupled cell functions.

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Animals Complement C3 Complement C3b Erythrocytes Granulocytes Guinea Pigs Humans Ligands Lymphocytes Macrophage-1 Antigen Membrane Proteins Mice Receptors, Complement Receptors, Complement 3b Receptors, Complement 3d Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

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M A Arnaout, H R Colten. 1984. Complement C3 receptors: structure and function.. https://doi.org/10.1016/0161-5890(84)90009-9

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