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PubMed · 6139526

Pregnancy and cystinuria.

M C Gregory·M A Mansell
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Abstract

46 pregnancies in patients with cystinuria treated with a high fluid intake alone or in combination with D-penicillamine resulted in 41 normal births. New stones formed in 18 pregnancies, with stone passage early in 4 of them. No patient required stone removal during pregnancy. Other pregnancy-related problems included hypertension and urinary-tract infection, which responded to conventional management. Assiduous maintenance of a sustained high fluid intake is even more important than usual during pregnancy and the puerperium. D-penicillamine appears relatively safe for severe cases, although most patients can be managed without it. With careful medical management stone-forming cystinurics can be safely conducted through pregnancy without increased risks to the mother or fetus.

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Birth WeightCystinuriaFemaleFollow-Up StudiesGenetic CounselingHumansPenicillaminePregnancyPregnancy ComplicationsRiskUrinary CalculiJournal Article

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M C Gregory, M A Mansell. 1983-11-19. Pregnancy and cystinuria.. https://doi.org/10.1016/s0140-6736(83)91213-8

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