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PubMed · 6137311

Electroreceptor functioning and morphology: functioning during histological fixation.

C Eigenhuis·J Doncker
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Abstract

The impact of chemical fixatives on electroreceptor functioning was studied electrophysiologically. The oxidative agents KMnO4 and OsO4 eliminate the sensory response within a few seconds, leaving a disturbed spike train pattern. Glutaraldehyde and formaldehyde eliminate the sensory response gradually in a period of several minutes; after that the afferent fibre shows repetitive activity. It is concluded that the physiological state of the electroreceptor is not preserved during chemical fixation; the ultimate morphological picture will reflect an unphysiological state, i.e. the response to the fixative.

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AnimalsElectrophysiologyFishesFixativesFormaldehydeGlutaralOsmium TetroxidePotassium PermanganateSensory Receptor CellsComparative StudyJournal ArticleResearch Support, Non-U.S. Gov't

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C Eigenhuis, J Doncker. 1983. Electroreceptor functioning and morphology: functioning during histological fixation.. https://doi.org/10.1016/0300-9629(83)90422-x

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