A conductance decrease after application of GABA to crayfish muscle fibers.

J Dudel

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PubMed · 547060

A conductance decrease after application of GABA to crayfish muscle fibers.

J Dudel

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Abstract

Relaxations after voltage steps of membrane current elicited by superfusion with low concentrations of GABA (up to 50 mumol/l) were measured. In many preparations, a conductance decrease due to GABA was observed. The response to GABA was shown to consist of two major components: the well known opening of synaptic chloride channels, and the closing of previously open channels, presumably permeable to K+ ions. The latter component could not be blocked by picrotoxin.

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Animals Astacoidea Electric Conductivity In Vitro Techniques Muscles gamma-Aminobutyric Acid Journal Article

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J Dudel. 1979. A conductance decrease after application of GABA to crayfish muscle fibers.. https://pubmed.ncbi.nlm.nih.gov/547060/

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