Search PubMed⌕ Search

PubMed · 520714

Differentiating minimal brain dysfunction and temperament.

Abstract

After referral to a pediatric neurologist for problems in behavior and learning, 61 children aged from three to seven years were assigned to one of four diagnostic groups: (1) minimal brain dysfunction (MBD); (2) hyperactivity; (3) learning disability; and (4) other criteria. Their temperament profiles were determined by the Behavioral Style Questionnaire. The disproportionately large number of children with more difficult temperament diagnoses in the referred population indicates that teachers and physicians may have mininterpreted a less adaptive behavioral style as evidence of neurological dysfunction. Those diagnosed clinically as having MBD were less adaptable, less persistent, more active and more negative than the control population. This suggests that MBD overlaps with difficult temperament. Children in the other three groups were temperamentally similar to the MBD group, which raises doubt about the advisability of diagnosing MBD on the basis of behavior alone. A comprehensive neurobehavioral profile is necessary to separate clearly the various factors contributing to problems in school performance.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

W B Carey, S C McDevitt, D Baker. 1979. Differentiating minimal brain dysfunction and temperament.. https://doi.org/10.1111/j.1469-8749.1979.tb01699.x

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

The natural history of temporal variant frontotemporal dementia.

BACKGROUND: The temporal variant of frontotemporal dementia (tvFTD) features asymmetric anterior temporal/amygdala degeneration as well as ventromedial frontal, insular, and inferoposterior temporal involvement. Left temporal atrophy has been linked to loss of semantic knowledge, whereas behavioral symptoms dominate the right temporal variant. OBJECTIVE: To investigate the first symptoms and the timing of subsequent symptoms in patients with left versus right tvFTD. METHODS: Twenty-six patients with tvFTD were identified. Six had right > left temporal atrophy (right temporal lobe variant [RTLV]) and were matched with six having comparable left > right temporal atrophy (left temporal lobe variant [LTLV]). Clinical records were reviewed to generate individualized symptom chronologies. RESULTS: In all patients, first symptoms involved semantics (4/6 LTLV, 1/6 RTLV), behavior (4/6 RTLV, 1/6 LTLV), or both (1 LTLV, 1 RTLV). Semantic loss began with anomia, word-finding difficulties, and repetitive speech, whereas the early behavioral syndrome was characterized by emotional distance, irritability, and disruption of physiologic drives (sleep, appetite, libido). After an average of 3 years, patients developed whichever of the two initial syndromes--semantic or behavioral--that they lacked at onset. A third stage, 5 to 7 years from onset, saw the emergence of disinhibition, compulsions, impaired face recognition, altered food preference, and weight gain. Compulsions in LTLV were directed toward visual, nonverbal stimuli, whereas patients with RTLV were drawn to games with words and symbols. CONCLUSIONS: The temporal variant of frontotemporal dementia follows a characteristic cognitive and behavioral progression that suggests early spread from one anterior temporal lobe to the other. Later symptoms implicate ventromedial frontal, insular, and inferoposterior temporal regions, but their precise anatomic correlates await confirmation.

Affective Symptoms↗

Personality traits and heart rate variability predict long-term cardiac mortality after myocardial infarction.

AIMS: To investigate personality traits and sympatho-vagal modulation of heart rate variability (HRV) during acute myocardial infarction (AMI), assessing their relationships and their long-term prognostic value. METHODS AND RESULTS: Psychological traits and 24 h HRV were prospectively investigated in 246 patients at discharge of an AMI. Patients were followed-up to 8 years for the occurrence of cardiac death and non-fatal reinfarction. Low coping and anxiety traits associated with reduced HRV characterized the study population. At univariate analysis, low emotional sensitivity and insecurity, relative tachycardia, reduced high frequency (HF), and low frequency power and pNN50 were predictive of cardiac death at 8-year follow-up. At multivariable analysis, low emotional sensitivity and low HF power remained predictive, with a relative risk of 4.18 (P=0.003) and 2.76 (P=0.007), respectively; also the type of infarction (Q vs. non-Q) and hospital length of stay were independent predictive variables. CONCLUSION: Anxiety and emotional sensitivity were significant predictors of 8-year cardiac mortality after AMI. Reduced HF power, a recognized marker of vagal withdrawal, increased the risk.

Affective Symptoms↗