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PubMed · 42709059

Effect of Various Types of Remineralizing Agents on the Remineralization of Mild and Moderate Defects Caused by Molar-Incisor Hypomineralization in Mexican Schoolchildren: A 12-month Follow-up Randomized Clinical Trial.

Alvaro García Pérez·Danely Minelli Muñiz Alquisiras·Jacqueline Adelina Rodríguez Chávez·Hugo Marcelo Flores Ruíz·Karen Angelina Mora Navarrete
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Abstract

PURPOSE: Using Laser-Induced Fluorescence (LIF), this study aimed to evaluate the effect of three remineralizing agents on permanent molars and incisors with both mild and moderate Molar-Incisor Hypomineralization (MIH) in 8-to-12-year-old Mexican schoolchildren. MATERIALS AND METHODS: In this randomized clinical trial, 104 children were selected to participate and then divided randomly into four groups: Group I: control, Oral-B kids (toothpaste); Group II: Fluor Protector (varnish); Group III: Clinpro White Varnish; and Group IV: MI Paste (CCP-ACP). Both varnishes were applied once every four weeks for twelve months for each group. Remineralization was evaluated by LIF at intervals of 1, 3, 6, 9, and 12 months. Paired-sample t-tests and repeated-measures ANOVA were performed, while the Greenhouse-Geisser correction was used to evaluate sphericity. RESULTS: The three test agents used increased the level of remineralization observed at the site of mild and moderate MIH defects over the course of twelve months (p0.001). A similar decrease in average LIF values was observed across the three treatment groups. CONCLUSIONS: The use of both fluoride varnishes and the CPP-ACP toothpaste was observed to promote the remineralization of both mild and moderate MIH defects.

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HumansChildTooth RemineralizationMolar HypomineralizationMexicoFollow-Up StudiesToothpastesFemaleCariostatic AgentsCaseinsMaleFluorides, TopicalMolarFluoride TreatmentIncisorDental Enamel HypoplasiaLasersDrug CombinationsPolyurethanesSilanesMolar-Incisor Hypomineralizationchildrenfluoride varnishlaser fluorescenceremineralizationJournal ArticleRandomized Controlled Trial

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Alvaro García Pérez, Danely Minelli Muñiz Alquisiras, Jacqueline Adelina Rodríguez Chávez, Hugo Marcelo Flores Ruíz, Karen Angelina Mora Navarrete. 2026-09-08. Effect of Various Types of Remineralizing Agents on the Remineralization of Mild and Moderate Defects Caused by Molar-Incisor Hypomineralization in Mexican Schoolchildren: A 12-month Follow-up Randomized Clinical Trial.. https://doi.org/10.3290/j.ohpd.c_2796

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Journal Article; Randomized Controlled Trial resourceChild subjectChildren subjectDrug Combinations subjectFemale subjectFollow-Up Studies subjectHumans subjectJournal Article subjectMale subjectPolyurethanes subjectRandomized controlled trials study

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