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PubMed · 42686331

Precision Oncology in Hepatopancreatobiliary Cancer Surgery.

Timothy E Newhook·Susan Tsai·Funda Meric-Bernstam
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Abstract

Advances in technology have allowed for the characterization of tumors at the genomic, transcriptomic, and proteomic levels. There are well-established targets for biliary tract cancers, with exciting new targets emerging in pancreatic ductal adenocarcinoma and potential targets in hepatocellular carcinoma. Taken together, these data suggest an important role for molecular profiling for personalizing cancer therapy in advanced disease and need for design of novel neoadjuvant studies to leverage these novel therapeutics perioperatively in the surgical patient.

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HumansPrecision MedicineLiver NeoplasmsPancreatic NeoplasmsBiliary Tract NeoplasmsMolecular Targeted TherapyCholangiocarcinomaGenomicsLiver cancerPancreatic cancerTargeted therapyJournal ArticleReview

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BibTeXRIS

Timothy E Newhook, Susan Tsai, Funda Meric-Bernstam. 2026. Precision Oncology in Hepatopancreatobiliary Cancer Surgery.. https://doi.org/10.1016/j.hoc.2026.05.026

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