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Beyond risk factors: A capacity framework for cancer survivorship research.

Keith M Bellizzi
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Abstract

Cancer survivorship research has identified numerous biological, behavioral, psychosocial, health care, and structural factors that influence recovery. However, these factors are typically studied as separate determinants rather than interacting influences. This commentary proposes available survivorship capacity as a unifying framework that explains how these diverse determinants collectively shape recovery and survivorship outcomes. Concepts from geroscience, health care delivery, rehabilitation, occupational therapy, and human factors science were synthesized to develop a conceptual framework of available survivorship capacity. The framework conceptualizes recovery as a function of the capacity remaining after competing health care and life demands draw upon survivors' finite physical, cognitive, emotional, social, financial, temporal, and health care resources. It generates testable propositions for measurement, intervention research, health care delivery, and implementation science while positioning available survivorship capacity as a common mechanism linking diverse determinants of recovery and identifying actionable targets for intervention. Available capacity offers a unifying conceptual framework for understanding heterogeneity in survivorship outcomes and intervention effectiveness while generating a research agenda for future survivorship science. Measuring and strengthening survivors' available capacity, while reducing unnecessary demands, may improve engagement in care, health behaviors, and long-term recovery.

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HumansSurvivorshipNeoplasmsCancer SurvivorsRisk FactorsDelivery of Health Carecancer survivorshipcapacityhealth equityimplementation sciencetreatment burdenJournal Article

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Keith M Bellizzi. 2026-09-01. Beyond risk factors: A capacity framework for cancer survivorship research.. https://doi.org/10.1002/cncr.70582

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