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Long-term consequences of childhood sexual abuse: An umbrella review of diagnostic meta-analyses.

Pol Thomas·Benjamin Fauquert·Nadine Kacenelenbogen·Giovanni Briganti·Charles Kornreich·Geert Goderis
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Abstract

BACKGROUND: Childhood sexual abuse (CSA) is a public health issue with an estimated worldwide prevalence of 12.7%, potentially leading to a host of lifelong and significant mental, physical, and behavioral health. The aim of this study was to comprehensively map the long-term consequences of childhood sexual abuse on physical, psychiatric, and behavioral health outcomes. METHODS: An umbrella review of meta-analyses of observational studies, registered on PROSPERO, was conducted to examine the diverse repercussions of childhood sexual abuse on adult health. Three bibliographic databases (PsycINFO, PubMed and Scopus) were searched from the inception of the respective databases to November 1st, 2022. Thirty-eight meta-analyses representing about 20 million individuals were analyzed, revealing a range of long-lasting consequences associated with CSA. RESULTS: Among physical pathologies, cervical cancer and functional neurological syndromes emerged as the most prominent, exhibiting significantly elevated odds ratios (ORs) of 4.18 IC95% and 3.30 IC95%, respectively. Sleep disorders and borderline personality disorders were the most prevalent mental health disorders associated with CSA, with respective ORs of 16.17 IC95% and 5.96 IC95%. Early sexual initiation (OR=3.59 IC95%, sexual assault (OR=3.36 IC95%, and prostitution (OR=3.24 IC95%) emerged as the most common behavioral consequences. Notably, no significant differences in the consequences of CSA were observed between men and women, except for reproductive health outcomes. DISCUSSION: When faced with certain pathologies, clinicians should consider and discuss sexual abuse with their patients. The consequences of abuse have a multifactorial origin, which is a weakness, as are the problems of defining abuse. The strength of our study is that it lists the consequences published in high-quality studies. CONCLUSION: This umbrella review provides compelling evidence of the profound and far-reaching impact of childhood sexual abuse on a broad spectrum of physical, mental, and behavioral health issues.

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HumansChild Abuse, SexualChildFemaleMeta-Analysis as TopicMental DisordersMaleAdultSleep Wake DisordersAdult Survivors of Child AbuseAbus sexuelsAbus sexuels sur mineursChild sexual abuseConsequencesConséquencesImpactSex offensesJournal ArticleSystematic ReviewMeta-Analysis

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Pol Thomas, Benjamin Fauquert, Nadine Kacenelenbogen, Giovanni Briganti, Charles Kornreich, Geert Goderis. 2026-04-09. Long-term consequences of childhood sexual abuse: An umbrella review of diagnostic meta-analyses.. https://doi.org/10.1016/j.encep.2026.02.007

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Adult subjectChild subjectFemale subjectHumans subjectJournal Article subjectJournal Article; Systematic Review; Meta-Analysis resourceMale subjectMeta-Analysis subjectSystematic reviews study

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