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PubMed · 41148201

On the Road to ROME: Defining Tissue-Liquid Concordance in Precision Oncology.

Erick F Saldanha·Lillian L Siu
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Abstract

A growing body of evidence has established liquid biopsy as a promising, noninvasive platform for genomic profiling. In this commentary, we build on findings from the multicenter, randomized phase II ROME trial and interrogate the challenges and opportunities of tissue-liquid profiling concordance in improving personalized cancer treatment and survival outcomes. See related article by Botticelli et al., p. 45.

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HumansPrecision MedicineNeoplasmsLiquid BiopsyBiomarkers, TumorMedical OncologyJournal ArticleComment

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Erick F Saldanha, Lillian L Siu. 2026-01-06. On the Road to ROME: Defining Tissue-Liquid Concordance in Precision Oncology.. https://doi.org/10.1158/1078-0432.ccr-25-3143

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