Search PubMedSearch

PubMed · 4033588

A simplified approach for modulation transfer function determinations in computed tomography.

Abstract

In order to determine the modulation transfer functions (MTF's) for x-ray computed tomography (CT) scanners, a measurement must be performed to obtain either the point spread function (PSF) or the line spread function (LSF). Thereafter, the usual procedure is to interpolate between the measured points and to determine the Fourier transforms numerically in order to obtain the MTF. Since this must usually be done many times to evaluate various reconstruction kernels and scan modalities, the process is tedious. Fortunately, it can be greatly simplified by utilizing a mathematical function to describe the PSF or LSF. Measured data for five CT scanners indicates that the PSF can usually be described by a Gaussian function. Hence, the MTF can be written in a generalized form eliminating the necessity of performing Fourier transformations each time. The MTF is determined directly from a single performance characteristic related to the full width at half maximum. The accuracy of the approach is compared with detailed MTF calculations for five CT scanners and it is shown to agree favorably with this data.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

E L Nickoloff, R Riley. A simplified approach for modulation transfer function determinations in computed tomography.. https://doi.org/10.1118/1.595706

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Two-way conversation with a mass spectrometer: nondestructive interactive mass spectrometry.

Most mass spectrometers employ destructive detection, so that it is necessary to repeat an experiment in order to vary even one parameter. In contrast, Fourier transform ion cyclotron resonance mass spectrometry offers nondestructive detection, so that ions remain available for further manipulation and redetection. Here, we show for the first time how to perform mass spectrometry interactively. Following each elementary experimental stage, such as ion generation, isolation, dissociation, or detection, the operator is free to choose and tailor the next stage without creating a fresh supply of ions. For example, we can test the effect of varying one parameter over several values without having to repeat the entire experimental event sequence each time, much like varying one letter or word in a sentence without having to rewrite the whole sentence. Such interactive control promises to speed development of complex experimental event sequences, as for optimizing the sequencing and structural analysis of tiny amounts (e.g., femtomoles or less) of biomacromolecules (peptides, nucleic acids, oligosaccharides).

Fourier Analysis

A dual approach to linogram imaging for MRI.

An alternate scheme for linogram image reconstruction, which is more logical from the viewpoint of its applicability to MRI data, is presented here. As a result, an intermediate step for this method, the direct Fourier method (DFM) gives the same results as the earlier developed general reconstruction algorithm labeled as the linogram method (LM). However, the two differ in the pathways taken to the solution. As a result, an intermediate step for DFM corresponds directly with the geometry of linogram data collected for MRI, in contrast to the LM reconstruction. The two reconstruction methods are delineated within the context of MRI data reconstruction, and applied to reconstruct images from linogram spin-echo data of a physical phantom, obtained on a clinical 1.5 T scanner.

Fourier Analysis

Theory of multiple NMR spin echoes of HD impurities in solid para-H2.

The theory of the formation of NMR multiple echoes for isotopic impurities (HD) in solid para-H2 has been developed for the case of weak quantum tunneling of the impurities. The results show that even for low tunneling rates (100-1000 Hz), NMR multiple echoes can be observed for experimentally accessible nuclear spin polarizations and can be used to provide an independent test for the existence of tunneling in the solid hydrogens.

Fourier Analysis