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PubMed · 4015257

Selective decrease of hypothalamic noradrenaline by cysteamine.

L Vécsei·M Balázs·I Bollók·G Telegdy
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Abstract

In dose studies, cysteamine pretreatment in a dose of 200 mg/kg or 300 mg/kg (subcutaneously, s.c.) markedly decreased the hypothalamic noradenaline content, but did not influence the dopamine and serotonin contents. In time studies, pretreatment with cysteamine in a dose of 300 mg/kg (s.c.) led to markedly decreased hypothalamic noradrenaline contents 4 hr, 8 hr and 12 hr after treatment. These results suggest that cysteamine treatment selectively decreases the hypothalamic noradrenaline content in dose- and time-related manners.

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AnimalsCysteamineDopamineHypothalamusMaleNorepinephrineRatsSerotoninTime FactorsJournal ArticleResearch Support, Non-U.S. Gov't

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L Vécsei, M Balázs, I Bollók, G Telegdy. 1985. Selective decrease of hypothalamic noradrenaline by cysteamine.. https://pubmed.ncbi.nlm.nih.gov/4015257/

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