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PubMed · 357320

Ascorbic acid, neutrophil function, and the immune response.

B Leibovitz·B V Siegel
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Abstract

The role of ascorbic acid is reviewed with regard to antimicrobial activity, interferon production, and humoral and cellular immune responses. Ascorbic acid appears to play a role in a number of neutrophil functions including increased chemotaxis, increased particulate ingestion, enhanced lysozyme-mediated non-oxidative killing, protection against the toxic effects of superoxide anion radical, inhibition of the halide-peroxide-myeloperoxidase system without a pronounced bactericidal effect, and stimulation of the hexose monophosphate shunt.

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AnimalsAntibody FormationAscorbic AcidBacteriaChemotaxis, LeukocyteHexosephosphatesHumansImmunity, CellularInterferonsLeukocyte CountNADH, NADPH OxidoreductasesNeutrophilsPeroxidesPhagocytosisJournal ArticleReview

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B Leibovitz, B V Siegel. 1978. Ascorbic acid, neutrophil function, and the immune response.. https://pubmed.ncbi.nlm.nih.gov/357320/

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