Search PubMed⌕ Search
Home/Archive/PubMed

PubMed · 2659611

[Copper].

P Elkoubi
View original source ↗Export metadata ↓

Abstract

Copper is an indispensable trace element for life. Four points are fundamental: copper is combined with essential enzymatic systems (oxidases, transaminases), copper is necessary for inclusion of iron in the molecule of hemoglobin, copper has a primordial role in the metabolism of molecule of hemoglobin, copper has a primordial role in the metabolism of collagen and elastin and some vascular diseases (aneurysms) are closely related to its lack, finally, there is an increase of plasmatic copper during cancerous diseases, which is significant even at an early time and usually proportional to the evolution.

Explore related subjects

Anemia, HypochromicAnimalsCollagenCopperElastinHepatolenticular DegenerationHumansMenkes Kinky Hair SyndromeMiceNeoplasmsRabbitsZincEnglish AbstractJournal ArticleReview

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

P Elkoubi. 1989. [Copper].. https://pubmed.ncbi.nlm.nih.gov/2659611/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed1992

Use of eluent containing surfactant for the liquid chromatographic analysis of porphyrins by direct serum injection.

A gradient elution reversed-phase high-performance liquid chromatographic method was developed for the direct serum injection analysis of porphyrins based on the use of eluent containing an anionic surfactant (sodium dodecyl sulfate) at a concentration below the critical micelle concentration to elute the serum proteins at the column void volume. Separation and detection performances were tested with a mixture of porphyrin standards containing uro-, heptacarboxylic-, hexacarboxylic-, pentacarboxylic-, copro-, zinc proto- and mesoporphyrin in a model serum consisting of 50 mg/ml bovine serum albumin. Average limit of detection is 0.06 pmol with a 10-microliter injection volume using fluorimetric excitation at the Soret band of porphyrins. The utility of this method for the direct serum injection analysis of porphyrins in human serum was evaluated by investigating serum samples from individuals suffering from iron-deficiency anemia and breast cancer.

Anemia, Hypochromic↗
PubMed1992

[New faces, forgotten diseases:border medical examination of asylum seekers' children 1990-1991].

Hitherto there has been no epidemiologic basis for the extent of initial medical examination (IME) of children of refugees. In Switzerland little data is published on the incidence of diseases among refugees; in particular information on their children is scarce. We report the results of IME in these children in the Canton of Zürich from 1 July 1990 to 30 June 1991. The Federal Refugees Office assigned 1487 children to the Canton of Zürich. 920 children (61.9%) were registered, 259 (17.4%) at Zürich Children's Hospital and 661 with local physicians (44.5%). The current IME included a tuberculin skin test only, with additional hepatitis B screening of children from high risk countries. At the Zürich Children's Hospital the IME was extended: every child was examined clinically and a history was taken. The findings in the children examined at the Zürich Children's Hospital were as follows: 171 (66%) were healthy. 5 children (2%) had tuberculosis, 2 (0.8%) vitamin D deficiency rickets, 5 (2%) had iron deficiency anemia, 9 had hepatitis B (all recovered), 25 (9.7%) had various skin diseases and in 51 a variety of diseases of differing clinical significance were diagnosed. The local physicians found a similar incidence of tuberculosis, vitamin D deficiency rickets, iron deficiency anemia and skin diseases.(ABSTRACT TRUNCATED AT 250 WORDS)

Anemia, Hypochromic↗