Search PubMed⌕ Search

PubMed · 2600992

Ifosfamide encephalopathy.

Abstract

We describe a case of reversible encephalopathy caused by the recently released anticancer drug Ifosfamide. The clinical course, role of EEG in monitoring and predicting encephalopathy, and putative mechanism of neurotoxicity is discussed. Short infusion times and/or prior CNS disease may increase the risk of encephalopathy.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

M M Danesh, C M De Giorgio, S R Beydoun, R A Kemp. 1989. Ifosfamide encephalopathy.. https://doi.org/10.3109/15563658908994426

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

A penalized likelihood approach to magnetic resonance image reconstruction.

Currently, images acquired via magnetic resonance imaging (MRI) and functional magnetic resonance imaging (fMRI) technology are reconstructed using the discrete inverse Fourier transform. While computationally convenient, this approach is not able to filter out noise. This is a serious limitation because the amount of noise in MRI and fMRI can be substantial. In this paper, we propose an alternative approach to reconstruction, based on penalized likelihood methodology. In particular, we focus on non-linear shrinkage estimators and show that this approach achieves a great reduction in integrated mean squared error (IMSE) of the estimated image with respect to the currently used estimator. This approach is extremely fast and easy to implement computationally. In addition, it can be combined with various alternative approaches to MR image reconstruction and can be easily adapted to other, non-MRI contexts, in which the observed data and the quantities of interest are related via a linear transform.

Brain Diseases↗