[Decrease in the radiation effect in the lymphoid organs of animals adapting to altitude].

V F Makeeva; G S Komolova; I A Egorov; V A Isabaeva

PubMed · 207927

[Decrease in the radiation effect in the lymphoid organs of animals adapting to altitude].

V F Makeeva·G S Komolova·I A Egorov·V A Isabaeva

Abstract

Adaptation to altitude hypoxia exerts a positive effect on the cell density of lymph organs of gamma-irradiated animals. It also reduces radiation degradation of DNA, its availability to DNase in the nuclear chromatin and disorders in the activity of DNA polymerases. The role of inhibition of radiation-induced degradation of chromatin DNA in the protective effect of altitude adaptation on the cell density of lymph organs is discussed.

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Adaptation, Physiological Altitude Animals DNA Deoxyribonucleases Enzyme Activation Gamma Rays Hypoxia Lymphoid Tissue Male Phosphoric Monoester Hydrolases Rats Spleen Time Factors Journal Article

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V F Makeeva, G S Komolova, I A Egorov, V A Isabaeva. [Decrease in the radiation effect in the lymphoid organs of animals adapting to altitude].. https://pubmed.ncbi.nlm.nih.gov/207927/

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