Toxigenics.

G A Evans

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PubMed · 1954346

Toxigenics.

G A Evans

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Abstract

Toxigenes are artificial genes created through genetic engineering which produce a native or modified toxin under the control of a tissue- or developmental-stage specific regulatory element. The toxigene is usually designed to make a gene product which, when produced intracellularly, leads to cell death or 'suicide'. The implantation and expression of toxigenes in transgenic animals may lead to cell-specific ablation which can be used to study developmental cell lineages and to create animal models of degenerative diseases.

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Animals Animals, Genetically Modified Gene Expression Genetic Engineering Immunotoxins Recombinant Proteins Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.Review

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G A Evans. 1991. Toxigenics.. https://pubmed.ncbi.nlm.nih.gov/1954346/

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