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PubMed · 190930

Epstein-Barr virus and human malignancy.

J L Ziegler·I T Magrath·P Gerber·P H Levine
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Abstract

The association of the Epstein-Barr virus and two human malignancies, Burkitt's lumphoma and nasopharyngeal carcinoma, is reviewed. Seroepidemiologic, virologic, and immunologic evidence is summarized, and several hypotheses regarding a possible etiologic role for the Epstein-Barr virus in these tumors are presented. With our current state of knowledge we cannot conclude that the Ipstein-Barr virus is oncogenic in man, nor can we yet ascertain the biological and clinical significance of its association with Burkitt's lymphoma and nasopharyngeal carcinoma.

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Antibodies, ViralAntigens, ViralBurkitt LymphomaCell Transformation, NeoplasticCocarcinogenesisDNA, ViralHerpesvirus 4, HumanHumansInfectious MononucleosisLymphocytesMembranesNasopharyngeal NeoplasmsRNA VirusesSkin TestsJournal ArticleReview

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J L Ziegler, I T Magrath, P Gerber, P H Levine. 1977. Epstein-Barr virus and human malignancy.. https://doi.org/10.7326/0003-4819-86-3-323

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