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PubMed · 16972711

Opening the adaptive toolbox.

Janet Wittes·Peter A Lachenbruch
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Abstract

This is a discussion of the following three papers appearing in this special issue on adaptive designs: 'A regulatory view on adaptive/flexible clinical trial design' by H. M. James Hung, Robert T. O'Neill, Sue-Jane Wang and John Lawrence; 'Confirmatory clinical trials with an adaptive design' by Armin Koch; and 'FDA's critical path initiative: A perspective on contributions of biostatistics' by Robert T. O'Neill.

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BiometryClinical Trials as TopicClinical Trials, Phase III as TopicData Interpretation, StatisticalResearch DesignCommentJournal Article

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Janet Wittes, Peter A Lachenbruch. 2006. Opening the adaptive toolbox.. https://doi.org/10.1002/bimj.200610240

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