Forcing the third dimension.

Nancy Boudreau; Valerie Weaver

doi:10.1016/j.cell.2006.04.019

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Forcing the third dimension.

Nancy Boudreau·Valerie Weaver

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Abstract

One goal of biomedical research is to reliably construct surrogate tissues for replacement therapy and to promote tissue regeneration. In this issue of Cell, Chun et al. (2006) provide insight into the molecular basis of tissue-specific differentiation. The authors show that remodeling of the extracellular matrix by the matrix metalloproteinase MT1-MMP contributes to the three-dimensional development of white adipose tissue in mice.

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Adipocytes Adipogenesis Adipose Tissue Animals Cell Differentiation Extracellular Matrix Matrix Metalloproteinase 14 Matrix Metalloproteinases Matrix Metalloproteinases, Membrane-Associated Mice Mice, Knockout Tissue Engineering Comment Journal Article Review

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Nancy Boudreau, Valerie Weaver. 2006-05-05. Forcing the third dimension.. https://doi.org/10.1016/j.cell.2006.04.019

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