ESCRT complexes assembled and GLUEd.

Sudharshan Eathiraj; David G Lambright

doi:10.1016/j.str.2006.03.005

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ESCRT complexes assembled and GLUEd.

Sudharshan Eathiraj·David G Lambright

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Abstract

The ESCRT-I, -II, and -III complexes act sequentially to sort monoubiquitinated transmembrane proteins into multivesicular bodies for targeted degradation in the lysosome. Two papers published in a recent issue of Cell provide insights into the structural organization and functional interactions of the ESCRT-I complex and ESCRT-II GLUE domain.

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Animals Cell Membrane Endosomes Lysosomes Models, Biological Models, Genetic Models, Molecular Molecular Conformation Phosphatidylinositol Phosphates Protein Binding Protein Conformation Protein Structure, Tertiary Protein Transport Ubiquitin News

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Sudharshan Eathiraj, David G Lambright. 2006. ESCRT complexes assembled and GLUEd.. https://doi.org/10.1016/j.str.2006.03.005

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