PubMed · 16215578
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M H Thornhill, R K Simmons, M N Pemberton, E D Theaker. 2005-10-08. Patch test value.. https://doi.org/10.1038/sj.bdj.4812825
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UNLABELLED: Mercury released from the surface of amalgam fillings has been linked to a variety of disorders, but without proof of correlation. Studies use surface counts to estimate this variable, but large-scale studies would require a tool to rapidly and accurately assess restoration surface area. OBJECTIVES: This study investigated digital analysis of conventional dental radiographs as a means of estimating amalgam surface area. METHODS: Amalgam fillings were placed in 40 typodont teeth, the surface areas of the restorations were determined by measuring standardized photomicrographs of each surface. The teeth were radiographed, and area of the radiographic image of the restorations was measured. Data were used to produce expressions to estimate actual area from radiographic area. RESULTS: Regression analyses showed that surface area estimation from radiographic area was more accurate than estimation from surface counts. The accuracy of the surface area count was further improved by combining the radiographic area with a photographic occlusal area measurement or surface count, the latter giving the highest correlation. CONCLUSIONS: This study demonstrated that two-dimensional dental radiographs may be used to estimate surface area of amalgam restorations.
Dental amalgam fillings containing approximately 50% mercury have been used for almost 200 years and have been controversial for almost the same time. Allegations of effects caused by amalgams have involved many diseases. Recent evidence that small amounts of mercury are continuously released from amalgam fillings has fuelled the controversy. This is a comprehensive review of the epidemiologic evidence for the safety of dental amalgam fillings, with an emphasis on methodological issues and identifying gaps in the literature. Studies show little evidence of effects on general chronic disease incidence or mortality. Limited evidence exists for an association with multiple sclerosis, but few studies on either Alzheimer's or Parkinson's diseases. The preponderance of evidence suggests no renal effects and that ill-defined symptom complexes, including chronic fatigue syndrome, are not caused by amalgams. There is little direct evidence that can be used to assess reproductive hazards. Overall, few relevant epidemiologic studies are available. Most prior assessments of possible amalgam health effects have been based on comparisons of dental mercury exposures with occupational exposures causing harm. However, the amalgam-exposed population contains a broader, possibly more susceptible, spectrum of people. Common limitations of population-based studies of dental amalgam effects include inadequate longitudinal exposure assessment and negative confounding by better access to dental care in higher socioeconomic groups. Better designed studies are needed, particularly for investigation of neurodegenerative diseases and effects on infants and children.
UNLABELLED: The use of dental amalgam is on the decline, yet its many advantages, including the contrast in colour with the tooth, increase the possibility that the patient's dentition will last a lifetime. CLINICAL RELEVANCE: Dental amalgam is still a viable restorative material. A recipe for the placing of better amalgam restorations along with clinical restorations of 30-year longevity using these techniques is presented.