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[Apoptosis: basic knowledge and applications].

P Marchetti
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Abstract

Apoptosis has become a most popular concept of cell death. What makes apoptosis particularly exciting for medicine is that its dysfunctions play a central role in the pathogenesis of several human diseases. This review summarizes the considerable knowledge about the cell death pathways. The purpose of this article is to provide a background of relevance to clinicians on apoptosis, and the rationale for future therapeutic interventions directed toward the apoptotic machinery.

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AnimalsApoptosisCaspasesDNA FragmentationDiagnosisEnzyme ActivationHumansNecrosisTherapeuticsEnglish AbstractJournal ArticleReview

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P Marchetti. 2005. [Apoptosis: basic knowledge and applications].. https://doi.org/10.1016/j.gyobfe.2005.06.015

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