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PubMed · 15919727

SECISDesign: a server to design SECIS-elements within the coding sequence.

Anke Busch·Sebastian Will·Rolf Backofen
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Abstract

SUMMARY: SECISDesign is a server for the design of SECIS-elements and arbitrary RNA-elements within the coding sequence of an mRNA. The element has to satisfy both structure and sequence constraints. At the same time, a certain amino acid similarity to the original protein has to be kept. The designed sequence can be used for recombinant expression of selenoproteins in Escherichia coli. AVAILABILITY: The server is available at http://www.bio.inf.uni-jena.de/Software/SECISDesign/index.html.

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Computer-Aided DesignDNA Transposable ElementsEscherichia coliHumansInternetProtein EngineeringProteinsRecombinant ProteinsSelenoproteinsSequence Analysis, ProteinSequence Analysis, RNASoftwareEvaluation StudyJournal Article

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Anke Busch, Sebastian Will, Rolf Backofen. 2005-05-26. SECISDesign: a server to design SECIS-elements within the coding sequence.. https://doi.org/10.1093/bioinformatics%2Fbti507

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