Integrating chromosome structure with function.

J B Rattner

doi:10.1007/bf00346003

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Integrating chromosome structure with function.

J B Rattner

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Abstract

Historically, the metaphase chromosome and its architecture has been viewed as the ultimate representation of a non-functional inactive chromatin state. Recent studies of centromere (kinetochore) function in concert with studies of the placement and function of several classes of chromosomal proteins now call for a reevaluation of this view. In this article a model of chromosome structure with functional correlates is presented. Evidence for the existence of a functional chromosomal region, the "Surface Domain" is discussed.

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Animals Cell Division Chromosomes Humans Journal Article Research Support, Non-U.S. Gov't Review

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J B Rattner. 1992. Integrating chromosome structure with function.. https://doi.org/10.1007/bf00346003

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