PubMed · 15620542
Knockout knockouts.
Abstract
Deletion of the genes for a variety of neuropeptides or their receptors has provided great insight into the physiological roles played by those peptides. Strikingly, several of these knockout models mature into very similar metabolic phenotypes, providing clues to the mechanisms underlying the regulation of glucose homeostasis, cardiovascular regulation and the hormonal response to stress.
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Willis K Samson, Meghan M Taylor. Knockout knockouts.. https://doi.org/10.1016/j.tem.2004.11.002
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