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PubMed · 15550233

[Persistent hyperinsulinemic hypoglycemia. Two case reports].

Norberto Sotelo-Cruz·Andrés Cordero-Olivares·Carlos Ramírez-Rodríguez·Guillermo López-Cervantes·Jaime Hurtado-Valenzuela·Brenda María López-Cervantes
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Abstract

We report two cases of infants who presented seizures and persistent hypoglycemia. In both infants, we established diagnosis of persistent hypoglycemia by hyperinsulinism (PHH); glycemic/insulinic ratio was > 0.3, and we found no pancreatic changes by means of other diagnostic procedures. The medical treatment consisted of hydrocortisone, diazoxide, and octreotide without response. Definitive treatment made was sub-total pancreatectomy; postoperatory evolution was satisfactory, and the histologic report showed changes in Langerhans islet of nesidioblastosis. We conclude that PHH and glucose/insulin ratio > 0.3 indicates that surgical treatment with pancreatectomy should not be delayed.

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FemaleHumansHyperinsulinismHypoglycemiaInfantInfant, NewbornMaleCase ReportsEnglish AbstractJournal Article

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Norberto Sotelo-Cruz, Andrés Cordero-Olivares, Carlos Ramírez-Rodríguez, Guillermo López-Cervantes, Jaime Hurtado-Valenzuela, Brenda María López-Cervantes. [Persistent hyperinsulinemic hypoglycemia. Two case reports].. https://pubmed.ncbi.nlm.nih.gov/15550233/

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